ENSMUSG00000062906


Mus musculus

Features
Gene ID: ENSMUSG00000062906
  
Biological name :Hdac10
  
Synonyms : Hdac10 / Histone deacetylase 10 / Q6P3E7
  
Possible biological names infered from orthology : Q969S8
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E3
Gene start: 89123307
Gene end: 89128700
  
Corresponding Affymetrix probe sets: 10431371 (MoGene1.0st)   1441832_at (Mouse Genome 430 2.0 Array)   1454775_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000080832
Ensembl peptide - ENSMUSP00000104971
NCBI entrez gene - 170787     See in Manteia.
MGI - MGI:2158340
RefSeq - XM_006520543
RefSeq - NM_199198
RefSeq - XM_006520537
RefSeq Peptide - NP_954668
swissprot - Q6P3E7
swissprot - D3Z7T4
Ensembl - ENSMUSG00000062906
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hdac10ENSDARG00000086458Danio rerio
 HDAC10ENSGALG00000041251Gallus gallus
 HDAC10ENSG00000100429Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hdac6 / Q9Z2V5 / Histone deacetylase 6 / Q9UBN7*ENSMUSG0000003116139
Hdac4 / Q6NZM9 / Histone deacetylase 4 / P56524*ENSMUSG0000002631318
Hdac5 / histone deacetylase 5 isoform 4 / Q9UQL6* / histone deacetylase 5*ENSMUSG0000000885517
Hdac7 / Q8C2B3 / Histone deacetylase 7 / Q8WUI4*ENSMUSG0000002247515
Hdac9 / histone deacetylase 9 / Q9UKV0*ENSMUSG000000046989


Protein motifs (from Interpro)
Interpro ID Name
 IPR000286  Histone deacetylase family
 IPR023696  Ureohydrolase domain superfamily
 IPR023801  Histone deacetylase domain
 IPR037138  Histone deacetylase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006476 protein deacetylation IEA
 biological_processGO:0016575 histone deacetylation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0070932 histone H3 deacetylation IEA
 cellular_componentGO:0000118 histone deacetylase complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004407 histone deacetylase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) IEA
 molecular_functionGO:0033558 protein deacetylase activity IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA


Pathways (from Reactome)
Pathway description
HDACs deacetylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Glycam1tm1.1(KOMP)Vlcg/Glycam1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Glycam1tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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