Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000242	impaired fertilization	"defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Grid2^ho-Jwg/Grid2^ho-Jwg Genetic Background: Not Specified
MP:0000436	abnormal head movements	"anomalous motion of the portion of the body containing the brain and organs of sight, hearing, taste, and smell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Grm1^rcw-2J/Grm1^rcw-2J Genetic Background: either: B6(129X1)-Grm1^rcw-2J/J or B6.129X1 Bax^tm1Sjk/J-Grm1^rcw-2J/J
MP:0000743	muscle spasms	"muscular twitching, cramps and seizures ; frequently associated with calcium deficiency, hypoparathyroidism, vitamin D deficiency or alkalosis " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Slc19a2^tm1Ejn/Slc19a2^tm1Ejn Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac Allelic Composition: Grid2^ho-8J/Grid2^ho-8J Genetic Background: B10.D2/nSnJ
MP:0000745	tremors	"repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Slc19a2^tm1Ejn/Slc19a2^tm1Ejn Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac Allelic Composition: Grid2^ho-17J/Grid2^ho-17J Genetic Background: C57BL/6J-Grid2^ho-17J/J Allelic Composition: Grid2^ho-20J/Grid2^ho-20J Genetic Background: B6(Cg)-Grid2^ho-20J/GrsrJ
MP:0000755	hindlimb paralysis	"loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0000841	abnormal hindbrain morphology	"malformed caudal region of the brain; includes cerebellum, pons and medulla oblongata" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]	Show Allelic Composition: Grid2^Lc/Grid2^Lc Genetic Background: B6CBACa A^w-J/A-Grid2^Lc/J
MP:0000849	abnormal cerebellum morphology	"any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Bcl2l2^{Gt(ROSA)41Sor}/Bcl2l2^{Gt(ROSA)41Sor},Grid2^ho-4J/Grid2^ho-4J Genetic Background: involves: 129S5/SvEvBrd * DBA/2J
MP:0000852	small cerebellum	"reduced size of cerebellum" [MGI:CLS, J:17203, J:67524]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Cacna1a^tm1Kano/Cacna1a^tm1Kano,Grid2^tm1(cre)Mwa/Grid2⁺ Genetic Background: involves: C57BL/6N Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0000854	abnormal cerebellum development	"malformed or incomplete differentiation of the part of the metencephalon that lies dorsal to the pons and medulla behind the brain stem and controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Grid2^Lc/Grid2^ho-Nancy Genetic Background: involves: C57BL/6 * STOCK Mitf^Mi-wh Allelic Composition: Grid2^Lc/Grid2^Lc Genetic Background: B6CBACa A^w-J/A-Grid2^Lc/J
MP:0000857	abnormal cerebellar foliation	"malformation of small offshoots of the cerebellar lobules" [Principles of Neural Science:ISBN 0-8385-8034-3, J:52951]	Show Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: BALB/cByJ-Grid2^Lc-J/+
MP:0000873	thin external granule cell layer	"reduced thickness of the transient layer of the cerebellar cortex which is composed of dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896]	Show Allelic Composition: Grid2^Lc/Grid2^ho-Nancy Genetic Background: involves: C57BL/6 * STOCK Mitf^Mi-wh
MP:0000875	abnormal cerebellar Purkinje cell layer	"any malformation or absence of the cell layer that lies just underneath the molecular layer of the cerebellar cortex; it contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer, and candelabrum interneurons are vertically oriented between the Purkinje cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Bcl2l2^{Gt(ROSA)41Sor}/Bcl2l2^{Gt(ROSA)41Sor},Grid2^ho-4J/Grid2^ho-4J Genetic Background: involves: 129S5/SvEvBrd * DBA/2J Allelic Composition: Bax^tm1Sjk/Bax^tm1Sjk,Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Bax^tm1Sjk/Bax⁺,Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6
MP:0000876	Purkinje cell degeneration	"a retrogressive impairment of function or destruction of the large neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex" [J:46854]	Show Allelic Composition: Grid2^Lc/Grid2^ho-Nancy Genetic Background: involves: C57BL/6 * STOCK Mitf^Mi-wh Allelic Composition: Grid2^Lc/Grid2⁺ Genetic Background: B6CBACa A^w-J/A-Grid2^Lc/J Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: BALB/cByJ-Grid2^Lc-J/+ Allelic Composition: Cacna1a^tm1Kano/Cacna1a^tm1Kano,Grid2^tm1(cre)Mwa/Grid2⁺ Genetic Background: involves: C57BL/6N
MP:0000877	abnormal Purkinje cell	"any structural anomaly of the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex; these inhibitory neurons provide the output of the cerebellar cortex through axons that project into the white matter, and extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells" [J:46140, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^Lc/Grid2^ho-Nancy Genetic Background: involves: C57BL/6 * STOCK Mitf^Mi-wh Allelic Composition: Grid2^{tm1(cre/PGR)Ksak}/Grid2^tm2Mim Genetic Background: involves: C57BL/6 Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Grid2^tm1Mmsh/Grid2^tm1Mmsh Genetic Background: involves: C57BL/6N Allelic Composition: Bcl2l2^{Gt(ROSA)41Sor}/Bcl2l2^{Gt(ROSA)41Sor},Grid2^ho-4J/Grid2^ho-4J Genetic Background: involves: 129S5/SvEvBrd * DBA/2J Allelic Composition: Bax^tm1Sjk/Bax^tm1Sjk,Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Cacna1a^tm1Kano/Cacna1a^tm1Kano,Grid2^tm1(cre)Mwa/Grid2⁺ Genetic Background: involves: C57BL/6N Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0000880	decreased Purkinje cell number	"fewer than normal neuronal cells that are located in the interface of the molecular and granular layers of the cerebellar cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:45302]	Show Allelic Composition: Bax^tm1Sjk/Bax^tm1Sjk,Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Bax^tm1Sjk/Bax⁺,Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Grid2^Lc/Grid2⁺ Genetic Background: involves: STOCK Mitf^Mi-wh Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0000886	abnormal cerebellar granule layer	"any malformation or absence of the innermost cortical layer of the cerebellum; contains densly packed small neurons, mostly granule cells with some Golgi cells are found at the outer border" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^Lc/Grid2^ho-Nancy Genetic Background: involves: C57BL/6 * STOCK Mitf^Mi-wh Allelic Composition: Grid2^ho-4J/Grid2^ho-4J Genetic Background: DBA/2J-Grid2^ho-4J/J Allelic Composition: Bax^tm1Sjk/Bax^tm1Sjk,Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Bax^tm1Sjk/Bax⁺,Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6
MP:0000889	abnormal cerebellar molecular layer	"any malformation or absence of the outermost layer of the cerebral cortex that contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Cacna1a^tm1Kano/Cacna1a^tm1Kano,Grid2^tm1(cre)Mwa/Grid2⁺ Genetic Background: involves: C57BL/6N Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0000890	thin cerebellar molecular layer	"reduced width of the outer of the three cortical layers of the cerebellum" [J:46854]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA
MP:0000897	abnormal midbrain	"malformation or malfunction associated with the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions, including eye movement and coordination of auditory and visual reflexes" [J:23882, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Grid2^Lc/Grid2^Lc Genetic Background: B6CBACa A^w-J/A-Grid2^Lc/J
MP:0000911	abnormal trigeminal motor nucleus morphology	"malformation or disorganization of the group of motor neurons innervating the muscles of mastication" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Grid2^Lc/Grid2^Lc Genetic Background: B6CBACa A^w-J/A-Grid2^Lc/J
MP:0000920	abnormal myelination	"atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Grid2^ho-cpr/Grid2^ho-cpr Genetic Background: involves: C57BL/10J * DBA/2J
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Egfr^tm1.1Dwt/Egfr^tm1.1Dwt Genetic Background: involves: 129S6/SvEvTac Allelic Composition: Grid2^ho-19J/Grid2^ho-19J Genetic Background: C57BL/6J-Grid2^ho-19J/GrsrJ Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0001389	abnormal eye movements	"deviation from the normal motility of the visual organs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: B6.Cg-Grid2^tm1Mim Allelic Composition: Grid2^tm1(cre)Mwa/Grid2^tm1(cre)Mwa Genetic Background: involves: C57BL/6N Allelic Composition: Grid2^ho-15J/Grid2^ho-15J Genetic Background: involves: C3HeB/Fe
MP:0001393	ataxia	"inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^Lc/Grid2^ho-Nancy Genetic Background: involves: C57BL/6 * STOCK Mitf^Mi-wh Allelic Composition: Grid2^tpr/Grid2^tpr Genetic Background: involves: B10.D2/nSnJ Allelic Composition: Grid2^ho-15J/Grid2^ho-15J Genetic Background: C3(Cg)-Grid2^ho-15J/GrsrJ Allelic Composition: Grid2^Lc/Grid2⁺ Genetic Background: B6CBACa A^w-J/A-Grid2^Lc/J Allelic Composition: Grid2^ho-17J/Grid2^ho-17J Genetic Background: C57BL/6J-Grid2^ho-17J/J Allelic Composition: Grid2^ho-4J/Grid2^ho-4J Genetic Background: DBA/2J-Grid2^ho-4J/J Allelic Composition: Grid2^ho-Jwg/Grid2^ho-Jwg Genetic Background: Not Specified Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Bcl2l2^{Gt(ROSA)41Sor}/Bcl2l2^{Gt(ROSA)41Sor},Grid2^ho-4J/Grid2^ho-4J Genetic Background: involves: 129S5/SvEvBrd * DBA/2J Allelic Composition: Grid2^ho-cpr/Grid2^ho-cpr Genetic Background: involves: C57BL/10J * DBA/2J Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: BALB/cByJ-Grid2^Lc-J/+ Allelic Composition: Grid2^{tm1(cre/PGR)Ksak}/Grid2^{tm1(cre/PGR)Ksak} Genetic Background: C57BL/6-Grid2^{tm1(cre/PGR)Ksak} Allelic Composition: Bax^tm1Sjk/Bax^tm1Sjk,Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Bax^tm1Sjk/Bax⁺,Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Grid2^Lc-J/Grid2⁺,Trp53^tm1Tyj/Trp53^tm1Tyj Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Grid2^Lc/Grid2⁺ Genetic Background: involves: STOCK Mitf^Mi-wh Allelic Composition: Grid2^ho-18J/Grid2^ho-18J Genetic Background: B6.Cg-Grid2^ho-18J/GrsrJ Allelic Composition: Grid2^ho-19J/Grid2^ho-19J Genetic Background: C57BL/6J-Grid2^ho-19J/GrsrJ Allelic Composition: Grid2^ho-15J/Grid2^ho-15J Genetic Background: involves: C3HeB/Fe Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0001399	hyperactivity	"general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]	Show Allelic Composition: Rora^sg/Rora⁺ Genetic Background: involves: C57BL/6J
MP:0001402	hypoactivity	"reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA
MP:0001405	impaired coordination	"reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^ho-4J/Grid2^ho-4J Genetic Background: DBA/2J-Grid2^ho-4J/J Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Grid2^{tm1(cre/PGR)Ksak}/Grid2^{tm1(cre/PGR)Ksak} Genetic Background: C57BL/6-Grid2^{tm1(cre/PGR)Ksak} Allelic Composition: Grid2^Lc/Grid2⁺ Genetic Background: involves: STOCK Mitf^Mi-wh Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: B6.Cg-Grid2^tm1Mim
MP:0001406	abnormal gait	"unusual or distinctive way of walking" [J:65038]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^tpr/Grid2^tpr Genetic Background: involves: B10.D2/nSnJ Allelic Composition: Grid2^ho-15J/Grid2^ho-15J Genetic Background: C3(Cg)-Grid2^ho-15J/GrsrJ Allelic Composition: Grid2^ho-16J/Grid2^ho-16J Genetic Background: C57BL/6J-Grid2^ho-16J/J Allelic Composition: Grid2^ho-17J/Grid2^ho-17J Genetic Background: C57BL/6J-Grid2^ho-17J/J Allelic Composition: Grid2^ho-Jwg/Grid2^ho-Jwg Genetic Background: Not Specified Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Grid2^ho/Grid2^ho Genetic Background: C57BLKS/J Allelic Composition: Grid2^ho-11J/Grid2^ho-11J Genetic Background: involves: C57BLKS/J Allelic Composition: Grid2^ho-13J/Grid2^ho-13J Genetic Background: B10.D2/nSnJ Allelic Composition: Grid2^ho-8J/Grid2^ho-8J Genetic Background: B10.D2/nSnJ Allelic Composition: Bcl2l2^{Gt(ROSA)41Sor}/Bcl2l2^{Gt(ROSA)41Sor},Grid2^ho-4J/Grid2^ho-4J Genetic Background: involves: 129S5/SvEvBrd * DBA/2J Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: BALB/cByJ-Grid2^Lc-J/+ Allelic Composition: Grid2^ho-Btlr/Grid2^ho-Btlr Genetic Background: C57BL/6J-Grid2^ho-Btlr Allelic Composition: Grid2^ho-Jic/Grid2^ho-Jic Genetic Background: either: B10.Cg-Grid2^ho-Jic H2^u or (involves: C57BL/10SnSg * DBA/2 * PL/J) Allelic Composition: Grid2^ho-20J/Grid2^ho-20J Genetic Background: B6(Cg)-Grid2^ho-20J/GrsrJ Allelic Composition: Grid2^ho-21J/Grid2^ho-21J Genetic Background: C57BL/6J-Grid2^ho-21J/GrsrJ Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0001407	short stride length	"reduced average distance between steps" [J:34193]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0001408	stereotypic behavior	"repetitive, invariant, perseverative motor patterns that do not appear to be purposeful" [What s wrong with my mouse?:ISBN 0-471-31639-3]	Show Allelic Composition: Grid2^ho/Grid2^ho Genetic Background: C57BLKS/J Allelic Composition: Grid2^ho-5J/Grid2^ho-5J Genetic Background: C57BLKS/J
MP:0001417	decreased exploration in new environment	"less amount of time spent investigating a new location" [J:79870]	Show Allelic Composition: Rora^sg/Rora⁺ Genetic Background: involves: C57BL/6J
MP:0001436	abnormal suckling behavior	"reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461]	Show Allelic Composition: Glra1^spd/Glra1^spd Genetic Background: B6C3Fe a/a-Glra1^spd/J
MP:0001440	abnormal grooming behavior	"defects in the standard of behavior of cleaning and/or keeping outward appearance tidy (self, mate or offspring)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Grid2^Lc/Grid2^Lc Genetic Background: B6CBACa A^w-J/A-Grid2^Lc/J
MP:0001463	abnormal spatial learning	"defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University]	Show Allelic Composition: Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺,Robo3^tm1.1Ache/Robo3^tm1.1Ache Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ
MP:0001475	reduced long term depression	"less than the normal, persistent activity-dependent decrease in synaptic efficacy between neurons, often following slow, weak stimulation of CA1 neurons" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science:ISBN 0-8385-8034-3]	Show Allelic Composition: Grid2^tm1Mmsh/Grid2^tm1Mmsh Genetic Background: involves: C57BL/6N
MP:0001504	abnormal posture	"atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: BALB/cByJ-Grid2^Lc-J/+
MP:0001513	limb grasping	"mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0001516	abnormal motor coordination/ balance	"altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Grid2^ho-Jwg/Grid2^ho-Jwg Genetic Background: Not Specified Allelic Composition: Grid2^Lc/Grid2⁺ Genetic Background: involves: STOCK Mitf^Mi-wh Allelic Composition: Grid2^ho/Grid2^ho Genetic Background: involves: C57BLKS/J Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0001523	impaired righting response	"reduced ability or greater amount of time needed to recover from supine position" [J:25565]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0001524	impaired limb coordination	"reduced ability to organize limb movements to execute complex maneuvers, such as walking" [J:64962, MGI:CLS, J:17123]	Show Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0001525	impaired balance	"reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^ho-4J/Grid2^ho-4J Genetic Background: DBA/2J-Grid2^ho-4J/J Allelic Composition: Grid2^ho-8J/Grid2^ho-8J Genetic Background: B10.D2/nSnJ Allelic Composition: Grid2^ho-Btlr/Grid2^ho-Btlr Genetic Background: C57BL/6J-Grid2^ho-Btlr
MP:0001527	athetotic walking movements	"characterized by slow, writhing involuntary movements of flexion, extension, pronation and supination of the paws and toes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:18984]	Show Allelic Composition: Grid2^ho-cpr/Grid2^ho-cpr Genetic Background: involves: C57BL/10J * DBA/2J
MP:0001745	increased circulating corticosterone level	"greater than the normal concentration of this adrenocortical steroid; induces glycogen deposition and regulates sodium conservation and potassium secretion" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:54931]	Show Allelic Composition: Rora^sg/Rora⁺ Genetic Background: involves: C57BL/6J
MP:0001748	increased circulating adrenocorticotropin level	"elevated concentration in the blood of the pituitary hormone that stimulates the secretion of adrenal cortical steroids and induces growth of the adrenal cortex " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:54931]	Show Allelic Composition: Rora^sg/Rora⁺ Genetic Background: involves: C57BL/6J
MP:0001899	absent long term depression	"lack of the normal, persistent activity-dependent decrease in synaptic efficacy between neurons, often following slow, weak stimulation of CA1 neurons" [Principles of Neural Science:ISBN 0-8385-8034-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA
MP:0001922	reduced male fertility	"reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]	Show Allelic Composition: Grid2^ho-Jwg/Grid2^ho-Jwg Genetic Background: Not Specified Allelic Composition: Grid2^ho-8J/Grid2^ho-8J Genetic Background: B10.D2/nSnJ
MP:0001923	reduced female fertility	"reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Grid2^ho-Jwg/Grid2^ho-Jwg Genetic Background: Not Specified Allelic Composition: Grid2^ho-8J/Grid2^ho-8J Genetic Background: B10.D2/nSnJ
MP:0001925	male infertility	"inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Grid2^ho/Grid2^ho Genetic Background: C57BLKS/J Allelic Composition: Grid2^ho-5J/Grid2^ho-5J Genetic Background: C57BLKS/J Allelic Composition: Grid2^ho-cpr/Grid2^ho-cpr Genetic Background: involves: C57BL/10J * DBA/2J Allelic Composition: Grid2^ho-Btlr/Grid2^ho-Btlr Genetic Background: C57BL/6J-Grid2^ho-Btlr Allelic Composition: Grid2^ho-18J/Grid2^ho-18J Genetic Background: B6.Cg-Grid2^ho-18J/GrsrJ
MP:0001961	abnormal reflex	"anomalies in an involuntary response to a peripheral stimulus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Hprt^{tm5(Myh7-GFP,Myh6-CFP)Unc}/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
MP:0002066	abnormal motor capabilities/coordination/movement	"altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Stat6^tm1Jni/Stat6^tm1Jni Genetic Background: involves: 129S/SvEv
MP:0002067	abnormal sensory capabilities/reflexes/nociception	"inability or altered ability to respond to a sensory stimulus" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0002082	postnatal lethality	"premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Stat6^tm1Jni/Stat6^tm1Jni Genetic Background: involves: 129S/SvEv
MP:0002161	abnormal fertility/fecundity	"reduced ability or inability to produce live offspring" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0002204	abnormal neurotransmitter physiology	"aberrant function or production of endogenous signaling molecules secreted by neurons that alter the behavior of neurons or effector cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Grid2^ho/Grid2^ho Genetic Background: involves: C57BLKS/J
MP:0002206	abnormal CNS synaptic transmission	"defect in the communication from a neuron to a target across a synapse in the central nervous system" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Grid2^tm1Mmsh/Grid2^tm1Mmsh Genetic Background: involves: C57BL/6N Allelic Composition: Cacna1a^tm1Kano/Cacna1a^tm1Kano,Grid2^tm1(cre)Mwa/Grid2⁺ Genetic Background: involves: C57BL/6 * C57BL/6N
MP:0002566	abnormal sexual interaction	"altered initiation, failure of initiation or incomplete mating behavior" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Grm1^rcw-2J/Grm1^rcw-2J Genetic Background: either: B6(129X1)-Grm1^rcw-2J/J or B6.129X1 Bax^tm1Sjk/J-Grm1^rcw-2J/J
MP:0002674	abnormal sperm motility	"anomalies in the mobility of the spermatozoa" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Grid2^ho-Jwg/Grid2^ho-Jwg Genetic Background: Not Specified
MP:0002757	reduced vertical activity	"lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA
MP:0002802	abnormal discrimination learning	"defects in the ability to exhibit a differential response to different stimuli that is achieved by the reinforcement of the desired response for each particular stimulus" [CFG:Center for Functional Genomics , Northwestern University]	Show Allelic Composition: Grid2^Lc/Grid2⁺ Genetic Background: involves: STOCK Mitf^Mi-wh
MP:0002804	abnormal motor learning	"defects in the ability to repeat a motor task requiring well coordinated movements and balance; measures cerebellar dependent learning" [CFG:Center for Functional Genomics , Northwestern University]	Show Allelic Composition: Grid2^ho-4J/Grid2^ho-4J Genetic Background: DBA/2J-Grid2^ho-4J/J
MP:0002807	abnormal eye blink conditioning behavior	"defects in the ability of an animal to learn to blink in anticipation of an aversive stimulus (e.g., an airpuff to the eyelid) following repeated pairings with a neutral stimulus (e.g., a tone); such learning is only adaptive if the animal is able to learn the precise timing between the conditioned and unconditioned stimuli " [CFG:Center for Functional Genomics , Northwestern University]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: B6.Cg-Grid2^tm1Mim
MP:0002882	abnormal neuron	"anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003]	Show Allelic Composition: Cacna1a^tm1Kano/Cacna1a^tm1Kano,Grid2^tm1(cre)Mwa/Grid2⁺ Genetic Background: involves: C57BL/6 * C57BL/6N
MP:0002910	abnormal excitatory postsynaptic currents	"defect in the size or duration of currents detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Grid2^tm1Mmsh/Grid2^tm1Mmsh Genetic Background: involves: C57BL/6N Allelic Composition: Cacna1a^tm1Kano/Cacna1a^tm1Kano,Grid2^tm1(cre)Mwa/Grid2⁺ Genetic Background: involves: C57BL/6 * C57BL/6N
MP:0003312	abnormal locomotor coordination	"reduced ability of an animal to maintain skillful and effective interaction of movements while engaging in locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^ho-4J/Grid2^ho-4J Genetic Background: DBA/2J-Grid2^ho-4J/J Allelic Composition: Grid2^ho/Grid2^ho Genetic Background: C57BLKS/J Allelic Composition: Grid2^ho-8J/Grid2^ho-8J Genetic Background: B10.D2/nSnJ
MP:0003313	abnormal locomotor activation	"altered ability or desire of an animal to initiate locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Grid2^ho/Grid2^ho Genetic Background: C57BLKS/J Allelic Composition: Grid2^ho-8J/Grid2^ho-8J Genetic Background: B10.D2/nSnJ
MP:0003894	abnormal Purkinje cell innervation	"malformation or absence of the supply of nerve fibers that connect to the Purkinje cells" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^ho-4J/Grid2^ho-4J Genetic Background: DBA/2J-Grid2^ho-4J/J Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA
MP:0004008	abnormal GABA receptor currents	"change in the measured amplitude or duration of response to stimulation of GABA receptors" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA
MP:0004097	abnormal cerebellar cortex morphology	"any structural anomaly of the thin mantle of gray matter that covers the surface of each cerebral hemisphere, including the six layers of nerve cells and the nerve pathways that connect them; together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Grid2^ho-4J/Grid2^ho-4J Genetic Background: DBA/2J-Grid2^ho-4J/J
MP:0004814	reduced linear vestibular evoked potential	"reduction of the biphasic response elicited by linear acceleration transients (usually jerk pulses to an animal s head)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Grid2^Lc/Grid2⁺ Genetic Background: B6CBACa A^w-J/A-Grid2^Lc/J Allelic Composition: Grid2^ho-4J/Grid2^ho-4J Genetic Background: DBA/2J-Grid2^ho-4J/J
MP:0004844	abnormal vestibuloocular reflex	"any anomaly in the nystagmus or deviation of the eyes in response to stimulation of the vestibular system in which impulses are conveyed from the semicircular canals and the otolithic membrane to the oculomotor nerve; this stimulation may occur by angular acceleration or deceleration or by irrigation of the ear with hot or cold water; normally, this reflex functions to maintain a stable retinal image during head rotation by generating appropriate compensatory eye movements" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: B6.Cg-Grid2^tm1Mim Allelic Composition: Grid2^Lc/Grid2⁺ Genetic Background: involves: C57BL/6 * CBA/CaGnLe
MP:0004996	abnormal CNS synapse formation	"any anomaly in the process of generating the initial connections between an axon and effector tissue or neuron" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^ho-4J/Grid2^ho-4J Genetic Background: DBA/2J-Grid2^ho-4J/J Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Bcl2l2^{Gt(ROSA)41Sor}/Bcl2l2^{Gt(ROSA)41Sor},Grid2^ho-4J/Grid2^ho-4J Genetic Background: involves: 129S5/SvEvBrd * DBA/2J Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0004998	decreased CNS synapse formation	"a reduction in the frequency of the process of generating the initial connections between an axon and effector tissue or neuron" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Bcl2l2^{Gt(ROSA)41Sor}/Bcl2l2^{Gt(ROSA)41Sor},Grid2^ho-4J/Grid2^ho-4J Genetic Background: involves: 129S5/SvEvBrd * DBA/2J
MP:0005039	hypoxia	"reduced concentration of O2 in the blood, alveoli or other tissues resulting in the decreased pressure of this component of body gases" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: BALB/cByJ-Grid2^Lc-J/+
MP:0005156	bradykinesia	"decreased spontaneity and movement" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83301]	Show Allelic Composition: Bcl2l2^{Gt(ROSA)41Sor}/Bcl2l2^{Gt(ROSA)41Sor},Grid2^ho-4J/Grid2^ho-4J Genetic Background: involves: 129S5/SvEvBrd * DBA/2J
MP:0005164	abnormal response to injury	"anomaly in the body s reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA
MP:0005191	head tilt	"condition in which the portion of the body containing the brain and organs of sight, hearing, taste, and smell lists to the side" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA
MP:0005202	lethargy	"mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Grid2^ho-Btlr/Grid2^ho-Btlr Genetic Background: C57BL/6J-Grid2^ho-Btlr
MP:0005402	abnormal action potential	"change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: B6.Cg-Grid2^tm1Mim
MP:0005424	jerky movement	"continuous, abrupt, faltering motions of the whole body or a portion of the body" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: Egfr^tm1.1Dwt/Egfr^tm1.1Dwt Genetic Background: involves: 129S6/SvEvTac
MP:0006035	abnormal mitochondrial morphology	"anomalous structure of the mitochondria" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Grid2^ho-4J/Grid2^ho-4J Genetic Background: DBA/2J-Grid2^ho-4J/J Allelic Composition: Bcl2l2^{Gt(ROSA)41Sor}/Bcl2l2^{Gt(ROSA)41Sor},Grid2^ho-4J/Grid2^ho-4J Genetic Background: involves: 129S5/SvEvBrd * DBA/2J
MP:0008260	abnormal autophagy	"abnormal catabolic process involving the degradation of a cell s own components through the lysosomal machinery" [MGI:honda "Hiraoki Onda, Mouse Genome Informatics Curator"]	Show Allelic Composition: Grid2^Lc/Grid2^ho-Nancy Genetic Background: involves: C57BL/6 * STOCK Mitf^Mi-wh
MP:0008572	abnormal Purkinje cell dendrite morphology	"any strucutral anomaly of the Purkinje cell body projections with hundreds of parallel spiny branches reaching up into the molecular layer" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^ho-4J/Grid2^ho-4J Genetic Background: DBA/2J-Grid2^ho-4J/J Allelic Composition: Bcl2l2^{Gt(ROSA)41Sor}/Bcl2l2^{Gt(ROSA)41Sor},Grid2^ho-4J/Grid2^ho-4J Genetic Background: involves: 129S5/SvEvBrd * DBA/2J Allelic Composition: Grid2^tm2Msmh/Grid2^tm2Msmh Genetic Background: C57BL/6-Grid2^tm2Msmh Allelic Composition: Bax^tm1Sjk/Bax^tm1Sjk,Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Cacna1a^tm1Kano/Cacna1a^tm1Kano,Grid2^tm1(cre)Mwa/Grid2⁺ Genetic Background: involves: C57BL/6N Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0008770	decreased survivor rate	"a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Grid2^ho-cpr/Grid2^ho-cpr Genetic Background: involves: C57BL/10J * DBA/2J
MP:0008892	abnormal sperm flagellum	"any strucutral anomaly of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MESH:A05.360.490.890.840]	Show Allelic Composition: Grid2^ho-Jwg/Grid2^ho-Jwg Genetic Background: Not Specified
MP:0008913	listing	"momentary, slow motions of the whole body from side to side sometimes followed by a sudden drop from an erect position" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: BALB/cByJ-Grid2^Lc-J/+ Allelic Composition: Grid2^ho-Btlr/Grid2^ho-Btlr Genetic Background: C57BL/6J-Grid2^ho-Btlr
MP:0008921	increased neurotransmitter release	"increased production or release of endogenous signaling molecules normally secreted by neurons that alter the behavior of neurons or effector cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cacna1a^tm1Kano/Cacna1a^tm1Kano,Grid2^tm1(cre)Mwa/Grid2⁺ Genetic Background: involves: C57BL/6N
MP:0008924	decreased granule neuron number	"reduction in the number of the small neurons of the granule cell layer that send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition"]	Show Allelic Composition: Bax^tm1Sjk/Bax⁺,Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0009141	increased prepulse inhibition	"increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: B6.Cg-Grid2^tm1Mim
MP:0009393	abnormal resting posture	"atypical position of the limbs compared to normal carriage when the body is inactive" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Grid2^ho-cpr/Grid2^ho-cpr Genetic Background: involves: C57BL/10J * DBA/2J
MP:0009435	abnormal miniature inhibitory postsynaptic currents	"defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an inhibitory impulse" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: involves: C57BL/6 * CBA
MP:0009514	titubation	"posture distinguished by a faltering gait while walking and/or a swaying motion of the trunk or head while resting; often is a characteristic of cellebellar disease" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: BALB/cByJ-Grid2^Lc-J/+
MP:0009538	abnormal synapse morphology	"any strucutral anomaly of the membrane junction site of a nerve cell to a target cell, such as another nerve cell, an effector cell, or a sensory receptor cell; transmission of nerve impulses may be mediated by chemical or by electrical means" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A08.850]	Show Allelic Composition: Grid2^tm2Msmh/Grid2^tm2Msmh Genetic Background: C57BL/6-Grid2^tm2Msmh
MP:0009546	absent gastric milk in neonates	"failure of nursing offspring to ingest milk as indicated by stomach content" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Grid2^Lc/Grid2^Lc Genetic Background: B6CBACa A^w-J/A-Grid2^Lc/J
MP:0009619	abnormal optokinetic reflex	"any anomaly in the nystagmus or deviation of the eyes in response to stimulation of the visual system by movement; normally, this reflex functions to stabilize a moving image on the retina" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Grid2^tm1Mim/Grid2^tm1Mim Genetic Background: B6.Cg-Grid2^tm1Mim Allelic Composition: Grid2^Lc/Grid2⁺ Genetic Background: involves: C57BL/6 * CBA/CaGnLe
MP:0009674	decreased birth weight	"reduction in average weight at birth compared to controls" [RGD:cur "Rat Genome Database submission"]	Show Allelic Composition: Grid2^Lc/Grid2^Lc Genetic Background: B6CBACa A^w-J/A-Grid2^Lc/J
MP:0009719	reduced cerebellar foliation	"the cerebellar lobules are reduced in size or number" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Grid2^Lc/Grid2^ho-Nancy Genetic Background: involves: C57BL/6 * STOCK Mitf^Mi-wh Allelic Composition: Bax^tm1Sjk/Bax⁺,Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6
MP:0009964	abnormal cerebellum lobule morphology	"any structural anomaly of the ten gyri of the cerebellar cortex" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3
MP:0010323	retropulsion	"a tendency to step or walk backwards" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0011083	complete lethality at weaning	"premature death at weaning age of all organisms of a given genotype in a population, often due to the inability to make the transition to solid food" [MGI:csmith]	Show Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: BALB/cByJ-Grid2^Lc-J/+
MP:0011087	complete neonatal lethality	"death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]	Show Allelic Composition: Grid2^Lc/Grid2^Lc Genetic Background: B6CBACa A^w-J/A-Grid2^Lc/J
MP:0011088	partial neonatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]	Show Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: BALB/cByJ-Grid2^Lc-J/+
MP:0011267	abnormal excitatory postsynaptic current amplitude	"anomaly in the size (height or maximum displacement) or shape of the evoked excitatory postsynaptic current wave" [MGI:csmith]	Show Allelic Composition: Cacna1a^tm1Kano/Cacna1a^tm1Kano,Grid2^tm1(cre)Mwa/Grid2⁺ Genetic Background: involves: C57BL/6N
MP:0011967	increased or absent threshold for auditory brainstem response	"increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]	Show Allelic Composition: Grid2^ho-18J/Grid2^ho-18J Genetic Background: B6.Cg-Grid2^ho-18J/GrsrJ
MP:0012490	abnormal cochlear VIII nucleus morphology	"any structural anomaly of two paired brainstem nuclei, the dorsal cochlear nucleus and the ventral cochlear nucleus, that lie dorsal and ventral, respectively, to the inferior cerebellar peduncle at the rostral pole of the medulla; the cochlear nuclei receive input from the cochlear nerve and send projections to the inferior colliculus, the medial geniculate, and other forebrain structures" [MGI:csmith]	Show Allelic Composition: Grid2^Lc/Grid2⁺ Genetic Background: involves: STOCK Mitf^Mi-wh
MP:0014185	cerebellum atrophy	"acquired diminution of the size of the cerebellum associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:Anna]	Show Allelic Composition: Btk^tm1Wk/Btk^tm1Wk,Cd40^tm1Geha/Cd40^tm1Geha Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Grid2^Lc/Grid2^ho-Nancy Genetic Background: involves: C57BL/6 * STOCK Mitf^Mi-wh Allelic Composition: Grid2^Lc-J/Grid2⁺ Genetic Background: involves: 129X1/SvJ * BALB/cByJ * C57BL/6 Allelic Composition: Grid2^ts3/Grid2^ts3 Genetic Background: C57BL/6J-Grid2^ts3

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr

ENSMUSG00000071424