Manteia

ENSMUSG00000072244

Mus musculus

Features

Gene ID:	ENSMUSG00000072244

Biological name :	Trim6

Synonyms :	Q8BGE7 / Trim6 / Tripartite motif-containing protein 6

Possible biological names infered from orthology :	Q9C030 / tripartite motif containing 6

Species:	Mus musculus

Chr. number:	7
Strand:	1
Band:	E3
Gene start:	104218793
Gene end:	104235152

Corresponding Affymetrix probe sets:	10555848 (MoGene1.0st) 1424448_at (Mouse Genome 430 2.0 Array) 1453624_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000095782 Ensembl peptide - ENSMUSP00000149805 Ensembl peptide - ENSMUSP00000119932 Ensembl peptide - ENSMUSP00000118859 Ensembl peptide - ENSMUSP00000116233 NCBI entrez gene - 94088 See in Manteia. MGI - MGI:2137352 RefSeq - XM_006508364 RefSeq - XM_017312407 RefSeq - XM_006508366 RefSeq - XM_006508365 RefSeq - NM_001013616 RefSeq Peptide - NP_001013637 swissprot - Q8BGE7 swissprot - D3Z7U8 swissprot - A0A1L1SS93 swissprot - D3YY77 swissprot - D3Z676 Ensembl - ENSMUSG00000072244

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
TRIM6	ENSG00000121236	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Trim34a / tripartite motif-containing 34A / TRIM34* / Q9BYJ4* / TRIM6-TRIM34* / TRIM6-TRIM34 readthrough* / tripartite motif containing 34*	ENSMUSG00000056144	52
Trim34b / TRIM34* / Q9BYJ4* / TRIM6-TRIM34* / TRIM6-TRIM34 readthrough* / tripartite motif containing 34*	ENSMUSG00000090215	52
Trim5 / Q9C035* / tripartite motif containing 5*	ENSMUSG00000060441	44
Trim12c / tripartite motif-containing 12C / TRIM5* / Q9C035* / tripartite motif containing 5*	ENSMUSG00000057143	44
P15533 / Trim30a / Mus musculus tripartite motif-containing 30A (Trim30a), transcript variant 2, mRNA. / TRIM5* / Q9C035* / tripartite motif containing 5*	ENSMUSG00000030921	44
Trim30c / TRIM5* / Q9C035* / tripartite motif containing 5*	ENSMUSG00000078616	43
Trim30d / tripartite motif-containing 30D / TRIM5* / Q9C035* / tripartite motif containing 5*	ENSMUSG00000057596	42
Trim21 / tripartite motif-containing 21 / P19474*	ENSMUSG00000030966	40
Trim68 / tripartite motif-containing 68 / Q6AZZ1*	ENSMUSG00000073968	38
Q5NCC9 / Trim58 / tripartite motif-containing 58 / Q8NG06*	ENSMUSG00000037124	37
Q99PQ2 / Trim11 / E3 ubiquitin-protein ligase TRIM11 / Q96F44* / tripartite motif containing 11*	ENSMUSG00000020455	34
Trim39 / tripartite motif-containing 39 / Q9HCM9* / TRIM39-RPP21* / TRIM39-RPP21 readthrough*	ENSMUSG00000045409	33
Trim38 / tripartite motif-containing 38 / O00635*	ENSMUSG00000064140	32
Q7TPM3 / Trim17 / E3 ubiquitin-protein ligase TRIM17 / Q9Y577* / tripartite motif containing 17*	ENSMUSG00000036964	31
Q3UWZ0 / Trim75 / tripartite motif-containing 75 / A6NK02* / TRIM75P* / tripartite motif containing 75, pseudogene*	ENSMUSG00000071089	28
Q99PQ1 / Trim12a / Tripartite motif-containing protein 12A / TRIM5* / Q9C035* / tripartite motif containing 5*	ENSMUSG00000066258	27
Trim61 / tripartite motif-containing 61	ENSMUSG00000109718	26
Q8VI40 / Trim60 / tripartite motif-containing 60 / Q495X7*	ENSMUSG00000053490	25

Protein motifs (from Interpro)

Interpro ID	Name
IPR000315	B-box-type zinc finger
IPR001841	Zinc finger, RING-type
IPR001870	B30.2/SPRY domain
IPR003877	SPRY domain
IPR003879	Butyrophylin-like, SPRY domain
IPR006574	SPRY-associated
IPR013083	Zinc finger, RING/FYVE/PHD-type
IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
IPR017907	Zinc finger, RING-type, conserved site
IPR020457	Zinc finger, B-box, chordata
IPR027370	RING-type zinc-finger, LisH dimerisation motif
IPR035828	TRIM6, PRY/SPRY domain

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000209	protein polyubiquitination	IDA
biological_process	GO:0002230	positive regulation of defense response to virus by host	IEA
biological_process	GO:0002741	positive regulation of cytokine secretion involved in immune response	IEA
biological_process	GO:0010628	positive regulation of gene expression	IMP
biological_process	GO:0010629	negative regulation of gene expression	IEA
biological_process	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	IEA
biological_process	GO:0010994	free ubiquitin chain polymerization	IEA
biological_process	GO:0016567	protein ubiquitination	IEA
biological_process	GO:0032496	response to lipopolysaccharide	IEA
biological_process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	IEA
biological_process	GO:0035458	cellular response to interferon-beta	IEA
biological_process	GO:0045071	negative regulation of viral genome replication	IEA
biological_process	GO:0045892	negative regulation of transcription, DNA-templated	IDA
biological_process	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	IEA
biological_process	GO:0070206	protein trimerization	IEA
biological_process	GO:0098586	cellular response to virus	IDA
biological_process	GO:2000679	positive regulation of transcription regulatory region DNA binding	IEA
biological_process	GO:2000737	negative regulation of stem cell differentiation	IMP
cellular_component	GO:0005622	intracellular	IEA
cellular_component	GO:0005634	nucleus	IMP
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005829	cytosol	IMP
molecular_function	GO:0005515	protein binding	IEA
molecular_function	GO:0008134	transcription factor binding	IPI
molecular_function	GO:0008270	zinc ion binding	IEA
molecular_function	GO:0016740	transferase activity	IEA
molecular_function	GO:0019901	protein kinase binding	IEA
molecular_function	GO:0030674	protein binding, bridging	IEA
molecular_function	GO:0046872	metal ion binding	IEA
molecular_function	GO:0061630	ubiquitin protein ligase activity	IEA
molecular_function	GO:1990782	protein tyrosine kinase binding	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr