ENSDARG00000002193


Danio rerio

Features
Gene ID: ENSDARG00000002193
  
Biological name :rho
  
Synonyms : P35359 / rho / rhodopsin
  
Possible biological names infered from orthology : P08100 / P15409
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 54076195
Gene end: 54077740
  
Corresponding Affymetrix probe sets: Dr.354.1.S1_at (Zebrafish Array)   NM_131084_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000011562
NCBI entrez gene - 30295     See in Manteia.
RefSeq - NM_131084
RefSeq Peptide - NP_571159
swissprot - B8JMK8
swissprot - P35359
ZFIN ID - ZDB-GENE-990415-271
Ensembl - ENSDARG00000002193
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RHOENSGALG00000020745Gallus gallus
 RHOENSG00000163914Homo sapiens
 RhoENSMUSG00000030324Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rhol / rhodopsin, like / RHO* / P15409* / P08100* / rhodopsin*ENSDARG0000007066679
Q9W6A6 / opn1mw4 / opsin 1 (cone pigments), medium-wave-sensitive, 4ENSDARG0000000063867
Q8AYM7 / opn1mw3 / opsin 1 (cone pigments), medium-wave-sensitive, 3ENSDARG0000004427966
Q9W6A5 / opn1mw1 / opsin 1 (cone pigments), medium-wave-sensitive, 1ENSDARG0000009700865
opn1mw2 / opsin 1 (cone pigments), medium-wave-sensitive, 2ENSDARG0000004428064
Q9W6A8 / opn1sw2 / opsin 1 (cone pigments), short-wave-sensitive 2ENSDARG0000001727446
opn1sw1 / opsin 1 (cone pigments), short-wave-sensitive 1 / P51491* / OPN1SW* / P03999* / Short-wave-sensitive opsin 1 * / opsin 1, short wave sensitive*ENSDARG0000004567740
Q8AYN0 / opn1lw2 / opsin 1 (cone pigments), long-wave-sensitive, 2 / OPN1MW* / P04000* / P0DN77* / O35599* / P0DN78* / P04001* / OPN1LW* / OPN1MW3* / OPN1MW2* / opsin 1, long wave sensitive...ENSDARG0000004486138
Q9W6A7 / opn1lw1 / opsin 1 (cone pigments), long-wave-sensitive, 1 / OPN1MW* / P04000* / P0DN77* / O35599* / P0DN78* / P04001* / OPN1LW* / OPN1MW3* / OPN1MW2* / opsin 1, long wave sensitive...ENSDARG0000004486237
parapinopsina / parapinopsin aENSDARG0000011697637
valopa / vertebrate ancient long opsin aENSDARG0000002115036
valopb / vertebrate ancient long opsin bENSDARG0000005418135
parapinopsinb / parapinopsin bENSDARG0000004467234
opn4a / opsin 4a (melanopsin) / OPN4* / Q9UHM6* / Q9QXZ9* / opsin 4* / Melanopsin *ENSDARG0000002209829
tmtops2b / teleost multiple tissue opsin 2bENSDARG0000002782229
tmtopsb / teleost multiple tissue opsin bENSDARG0000003224628
tmtops3a / teleost multiple tissue opsin 3aENSDARG0000003646028
parietopsinENSDARG0000005205628
tmtops3b / teleost multiple tissue opsin 3bENSDARG0000009062928
tmtops2a / teleost multiple tissue opsin 2aENSDARG0000006151527


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000732  Rhodopsin
 IPR001760  Opsin
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR019477  Rhodopsin, N-terminal
 IPR027430  Visual pigments (opsins) retinal binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0007602 phototransduction IEA
 biological_processGO:0009583 detection of light stimulus IDA
 biological_processGO:0016038 absorption of visible light IDA
 biological_processGO:0016056 rhodopsin mediated signaling pathway NAS
 biological_processGO:0018298 protein-chromophore linkage IEA
 biological_processGO:0050896 response to stimulus IEA
 cellular_componentGO:0001750 photoreceptor outer segment IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0097381 photoreceptor disc membrane ISS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005502 11-cis retinal binding ISS
 molecular_functionGO:0008020 G-protein coupled photoreceptor activity IDA
 molecular_functionGO:0009881 photoreceptor activity IDA
 molecular_functionGO:0016918 retinal binding NAS


Pathways (from Reactome)
Pathway description
The canonical retinoid cycle in rods (twilight vision)
Activation of the phototransduction cascade
Inactivation, recovery and regulation of the phototransduction cascade
G alpha (i) signalling events
Opsins
VxPx cargo-targeting to cilium


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000020191 ppef1 / protein phosphatase, EF-hand calcium binding domain 1 / O35655* / O14829* / protein phosphatase with EF-hand domain 1* / Serine/threonine-protein phosphatase with EF-hands 1 *  / reaction
 ENSDARG00000002193 rho / P35359 / rhodopsin / P08100*  / reaction
 ENSDARG00000044861 Q8AYN0 / opn1lw2 / opsin 1 (cone pigments), long-wave-sensitive, 2 / OPN1MW* / P04000* / P0DN77* / O35599* / P0DN78* / P04001* / OPN1LW* / OPN1MW3* / OPN1MW2* / opsin 1, long wave sensitive...  / reaction
 ENSDARG00000044199 gnat1 / guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 / P20612* / P11488* / G protein subunit alpha transducin 1* / guanine nucleotide binding pro...  / complex / reaction
 ENSDARG00000042529 gnat2 / guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 / P50149* / P19087* / G protein subunit alpha transducin 2* / guanine nucleotide binding pro...  / complex / reaction
 ENSDARG00000044862 Q9W6A7 / opn1lw1 / opsin 1 (cone pigments), long-wave-sensitive, 1 / OPN1MW* / P04000* / P0DN77* / O35599* / P0DN78* / P04001* / OPN1LW* / OPN1MW3* / OPN1MW2* / opsin 1, long wave sensitive...  / reaction
 ENSDARG00000056831 gng2 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / P63213* / G protein subunit gamma 2*  / complex / reaction
 ENSDARG00000070666 rhol / rhodopsin, like / RHO* / P15409* / P08100* / rhodopsin*  / reaction
 ENSDARG00000090454 gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*  / complex / reaction
 ENSDARG00000067920 rab8a / RAB8A, member RAS oncogene family / P55258* / P61006*  / complex
 ENSDARG00000104372 gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*  / complex / reaction
 ENSDARG00000055534 grk7b / Q1XHL7 / G protein-coupled receptor kinase 7b / GRK7* / Q8WTQ7* / G protein-coupled receptor kinase 7*  / reaction
 ENSDARG00000058803 grk1a / G protein-coupled receptor kinase 1 a / GRK1* / Q15835* / G protein-coupled receptor kinase 1*  / reaction
 ENSDARG00000070448 grk4 / G protein-coupled receptor kinase 4 / O70291* / P32298*  / reaction
 ENSDARG00000020602 grk7a / Q49HM9 / G protein-coupled receptor kinase 7a / GRK7* / Q8WTQ7* / G protein-coupled receptor kinase 7*  / reaction






 

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