ENSDARG00000016181


Danio rerio

Features
Gene ID: ENSDARG00000016181
  
Biological name :trim33
  
Synonyms : trim33 / tripartite motif containing 33
  
Possible biological names infered from orthology : Q9UPN9
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 10956468
Gene end: 11004739
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000113637
Ensembl peptide - ENSDARP00000146766
Ensembl peptide - ENSDARP00000025140
NCBI entrez gene - 324053     See in Manteia.
RefSeq - NM_001002871
RefSeq Peptide - NP_001002871
swissprot - B0S5U2
swissprot - F1R9F9
ZFIN ID - ZDB-GENE-030131-2773
Ensembl - ENSDARG00000016181
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TRIM33ENSGALG00000001976Gallus gallus
 Q9UPN9ENSG00000197323Homo sapiens
 Trim33ENSMUSG00000033014Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
trim24 / tripartite motif containing 24ENSDARG0000010335028
trim33l / tripartite motif containing 33, likeENSDARG0000008612618
trim66 / tripartite motif containing 66 / O15016* / Q924W6*ENSDARG0000005433218
trim71 / E7FAM5 / tripartite motif containing 71, E3 ubiquitin protein ligase / Q2Q1W2* / Q1PSW8* / tripartite motif containing 71*ENSDARG0000007559311
trim2a / tripartite motif containing 2a / TRIM2* / Q9ESN6* / Q9C040* / tripartite motif containing 2*ENSDARG0000003181710
trim45 / tripartite motif containing 45 / Q6PFY8* / Q9H8W5* / Tripartite motif-containing protein 45 *ENSDARG000000767819
trim3b / tripartite motif containing 3b / TRIM3* / Q9R1R2* / O75382* / tripartite motif containing 3*ENSDARG000000053979
trim3a / tripartite motif containing 3a / TRIM3* / Q9R1R2* / O75382* / tripartite motif containing 3*ENSDARG000000637119
trim2b / tripartite motif containing 2b / TRIM2* / Q9ESN6* / Q9C040* / tripartite motif containing 2*ENSDARG000000761747


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001487  Bromodomain
 IPR001841  Zinc finger, RING-type
 IPR001965  Zinc finger, PHD-type
 IPR003649  B-box, C-terminal
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Downregulation of SMAD2/3:SMAD4 transcriptional activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood quality , abnormal
blood morphology , abnormal
blood decreased amount , abnormal
Show

 ZFA:0000012 central nervous system central nervous system macrophage decreased amount , abnormal
Show

 ZFA:0000033 intermediate cell mass of mesoderm intermediate cell mass of mesoderm physical object quality , abnormal
Show

 ZFA:0000040 median fin fold median fin fold edge shape , abnormal
median fin fold rough , abnormal
Show

 ZFA:0000084 yolk yolk macrophage increased amount , abnormal
Show

 ZFA:0000094 blood island blood island lacks all parts of type erythroid progenitor cell , abnormal
blood island apoptotic process increased occurrence , abnormal
Show

 ZFA:0000107 eye eye macrophage decreased amount , abnormal
Show

 ZFA:0000108 fin fin degenerate , abnormal
fin erose , abnormal
Show

 ZFA:0000114 heart heart lacks all parts of type nucleate erythrocyte , abnormal
Show

 ZFA:0000128 midbrain midbrain macrophage decreased amount , abnormal
Show

 ZFA:0000152 retina retina macrophage decreased amount , abnormal
retina macrophage mislocalised , abnormal
Show

 ZFA:0000186 common cardinal vein common cardinal vein lacks all parts of type nucleate erythrocyte , abnormal
Show

 ZFA:0000292 surface structure surface structure quality , abnormal
Show

 ZFA:0000445 optic tectum optic tectum lacks parts or has fewer parts of type microglial cell , abnormal
Show

 ZFA:0000473 trunk musculature trunk musculature quality , abnormal
trunk musculature morphology , abnormal
Show

 ZFA:0001058 caudal fin caudal fin has extra parts of type iridophore , abnormal
Show

 ZFA:0001069 ventral fin fold ventral fin fold neutrophil decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
whole organism macrophage spatial pattern , abnormal
whole organism macrophage amount , ameliorated
whole organism apoptotic process increased occurrence , abnormal
Show

 ZFA:0001114 head head macrophage decreased amount , abnormal
Show

 ZFA:0001117 post-vent region post-vent region ventral larval melanophore stripe has extra parts of type iridophore , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin rough , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0005221 dorsal larval melanophore stripe dorsal larval melanophore stripe has extra parts of type iridophore , abnormal
Show

 ZFA:0005224 yolk larval melanophore stripe yolk larval melanophore stripe has extra parts of type iridophore , abnormal
Show

 ZFA:0005561 vitreous vitreous macrophage decreased amount , abnormal
Show

 ZFA:0005597 median fin median fin shape , abnormal
median fin decreased area , abnormal
Show

 ZFA:0009015 erythroid progenitor cell erythroid progenitor cell apoptotic , abnormal
Show

 ZFA:0009090 pigment cell pigment cell quality , abnormal
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 ZFA:0009141 macrophage macrophage decreased amount , abnormal
macrophage aggregated , abnormal
Show

 ZFA:0009199 iridophore iridophore irregular spatial pattern , abnormal
iridophore degree of pigmentation , abnormal
iridophore increased amount , abnormal
iridophore displaced to median fin , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
nucleate erythrocyte increased size , abnormal
nucleate erythrocyte basophilic , abnormal
Show

 ZFA:0009327 neutrophil neutrophil decreased amount , abnormal
neutrophil aggregated , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000036096 smad3a / SMAD family member 3a / SMAD3* / Q8BUN5* / P84022* / SMAD family member 3* / Mothers against decapentaplegic homolog 3 *  / complex / reaction
 ENSDARG00000006389 smad2 / Q9I9P9 / SMAD family member 2 / Q62432* / Q15796* / Mothers against decapentaplegic homolog 2 *  / complex / reaction
 ENSDARG00000075226 smad4a / SMAD family member 4a / SMAD4* / Q13485* / SMAD family member 4*  / reaction / complex






 

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