Manteia

ENSDARG00000016676

Danio rerio

Features

Gene ID:	ENSDARG00000016676

Biological name :	gnao1a

Synonyms :	gnao1a / guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a

Possible biological names infered from orthology :	GNAO1 / G protein subunit alpha o1 / guanine nucleotide binding protein, alpha O / P09471 / P18872

Species:	Danio rerio

Chr. number:	18
Strand:	1
Band:
Gene start:	22793465
Gene end:	22975655

Corresponding Affymetrix probe sets:	Dr.11214.1.A1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000124253 Ensembl peptide - ENSDARP00000124476 NCBI entrez gene - 393760 See in Manteia. swissprot - F8W442 swissprot - Q6PBP1 ZFIN ID - ZDB-GENE-040426-1757 Ensembl - ENSDARG00000016676

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
GNAO1	ENSGALG00000003163	Gallus gallus
GNAO1	ENSG00000087258	Homo sapiens
Gnao1	ENSMUSG00000031748	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
gnao1b / guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b / GNAO1* / P18872* / P09471* / G protein subunit alpha o1* / guanine nucleotide binding p...	ENSDARG00000036058	89
gnai2b / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b / GNAI2* / P08752* / P04899* / G protein subunit alpha i2* / guanine nucleotide binding pro...	ENSDARG00000017294	69
gnai1 / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	ENSDARG00000021647	69
gnai3 / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 / GNAI1* / B2RSH2* / P08754* / P63096* / Q9DC51* / G protein subunit alpha i1* / G protein su...	ENSDARG00000030644	68
gnai2a / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a / GNAI2* / P08752* / P04899* / G protein subunit alpha i2* / guanine nucleotide binding pro...	ENSDARG00000018174	67
gnaia / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a	ENSDARG00000044760	66
gnat1 / guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 / P20612* / P11488* / G protein subunit alpha transducin 1* / guanine nucleotide binding pro...	ENSDARG00000044199	62
gnat2 / guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 / P50149* / P19087* / G protein subunit alpha transducin 2* / guanine nucleotide binding pro...	ENSDARG00000042529	59
GNAZ / G protein subunit alpha z / P19086*	ENSDARG00000099844	58
gna14a / guanine nucleotide binding protein (G protein), alpha 14a / GNA14* / P30677* / O95837* / G protein subunit alpha 14* / guanine nucleotide binding protein, alpha 14*	ENSDARG00000025013	50
gnaq / guanine nucleotide binding protein (G protein), q polypeptide / P50148* / P21279* / G protein subunit alpha q* / guanine nucleotide binding protein, alpha q polypeptide*	ENSDARG00000011487	49
gna11b / guanine nucleotide binding protein (G protein), alpha 11b (Gq class)	ENSDARG00000053326	48
gna11a / guanine nucleotide binding protein (G protein), alpha 11a (Gq class)	ENSDARG00000010002	47
gna14 / guanine nucleotide binding protein (G protein), alpha 14	ENSDARG00000035178	47
gnav1 / guanine nucleotide binding protein (G protein) alpha v1	ENSDARG00000043006	45
gna15.1 / guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1 / GNA15* / P30679* / P30678* / G protein subunit alpha 15* / guanine nucleotide binding pro...	ENSDARG00000016364	44
gna15.2 / gna15.3 / guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 2 / GNA15* / P30679* / P30678* / G protein subunit alpha 15* / guanine nucleotide b...	ENSDARG00000056654	44
gna13b / guanine nucleotide binding protein (G protein), alpha 13b / GNA13* / Q14344* / G protein subunit alpha 13*	ENSDARG00000037924	43
gna13a / guanine nucleotide binding protein (G protein), alpha 13a / GNA13* / Q14344* / P27601* / G protein subunit alpha 13* / guanine nucleotide binding protein, alpha 13*	ENSDARG00000073765	42
gna12a / guanine nucleotide binding protein (G protein) alpha 12a / GNA12* / Q03113* / P27600* / G protein subunit alpha 12* / guanine nucleotide binding protein, alpha 12*	ENSDARG00000025826	42

Protein motifs (from Interpro)

Interpro ID	Name
IPR001019	Guanine nucleotide binding protein (G-protein), alpha subunit
IPR001408	G-protein alpha subunit, group I
IPR011025	G protein alpha subunit, helical insertion
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway	IBA
biological_process	GO:0007212	dopamine receptor signaling pathway	IBA
cellular_component	GO:0005834	heterotrimeric G-protein complex	IBA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003924	GTPase activity	IBA
molecular_function	GO:0004871	obsolete signal transducer activity	IBA
molecular_function	GO:0005525	GTP binding	IEA
molecular_function	GO:0019001	guanyl nucleotide binding	IEA
molecular_function	GO:0031683	G-protein beta/gamma-subunit complex binding	IBA
molecular_function	GO:0031821	G-protein coupled serotonin receptor binding	IBA
molecular_function	GO:0031852	mu-type opioid receptor binding	IBA
molecular_function	GO:0051430	corticotropin-releasing hormone receptor 1 binding	IBA

Pathways (from Reactome)

Pathway description

PLC beta mediated events

G-protein activation

Ca2+ pathway

Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000104372	gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*	/ complex
ENSDARG00000056831	gng2 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / P63213* / G protein subunit gamma 2*	/ complex
ENSDARG00000090454	gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*	/ complex

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr