ENSDARG00000018432


Danio rerio

Features
Gene ID: ENSDARG00000018432
  
Biological name :m6pr
  
Synonyms : m6pr / mannose-6-phosphate receptor (cation dependent)
  
Possible biological names infered from orthology : Cation-dependent mannose-6-phosphate receptor / P20645 / P24668
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 17578607
Gene end: 17586883
  
Corresponding Affymetrix probe sets: Dr.11519.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000121745
Ensembl peptide - ENSDARP00000018076
Ensembl peptide - ENSDARP00000144386
NCBI entrez gene - 406486     See in Manteia.
swissprot - E9QEX8
swissprot - Q6P032
ZFIN ID - ZDB-GENE-040426-2285
Ensembl - ENSDARG00000018432
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 M6PRENSGALG00000031681Gallus gallus
 M6PRENSG00000003056Homo sapiens
 M6prENSMUSG00000007458Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000296  Cation-dependent mannose-6-phosphate receptor
 IPR009011  Mannose-6-phosphate receptor binding domain superfamily
 IPR028927  Mannose-6-phosphate receptor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006622 protein targeting to lysosome IMP
 biological_processGO:0015761 mannose transmembrane transport IEA
 cellular_componentGO:0000323 lytic vacuole IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005537 mannose binding IDA
 molecular_functionGO:0015578 mannose transmembrane transporter activity IEA
 molecular_functionGO:0019904 protein domain specific binding IPI


Pathways (from Reactome)
Pathway description
Lysosome Vesicle Biogenesis
Retrograde transport at the Trans-Golgi-Network
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018432 m6pr / mannose-6-phosphate receptor (cation dependent) / P20645* / P24668* / Cation-dependent mannose-6-phosphate receptor *  / complex
 ENSDARG00000099258 vps52 / vacuolar protein sorting 52 homolog (S. cerevisiae) / Q8C754* / Q8N1B4* / VPS52, GARP complex subunit*  / reaction
 ENSDARG00000045027 rab9a / RAB9A, member RAS oncogene family / Rab9* / Q9R0M6* / P51151* / RAB9, member RAS oncogene family*  / complex
 ENSDARG00000069324 vps53 / vacuolar protein sorting 53 homolog (S. cerevisiae) / Q5VIR6* / Q8CCB4* / VPS53, GARP complex subunit*  / reaction
 ENSDARG00000045065 vti1a / vesicle transport through interaction with t-SNAREs 1A / O89116* / Q96AJ9*  / reaction
 ENSDARG00000075030 stx10 / syntaxin 10 / O60499*  / reaction
 ENSDARG00000070161 vamp3 / vesicle-associated membrane protein 3 (cellubrevin) / P63024* / Q15836* / vesicle associated membrane protein 3*  / complex
 ENSDARG00000003307 stx16 / syntaxin 16 / Q8BVI5* / O14662* / STX16-NPEPL1* / STX16-NPEPL1 readthrough (NMD candidate)*  / reaction
 ENSDARG00000112165 Q6GQN7 / rabepk / Rab9 effector protein with kelch motifs / Q7Z6M1*  / complex






 

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