ENSDARG00000020007


Danio rerio

Features
Gene ID: ENSDARG00000020007
  
Biological name :col1a2
  
Synonyms : col1a2 / collagen, type I, alpha 2
  
Possible biological names infered from orthology : Collagen alpha-2(I) chain / collagen type I alpha 2 chain / P08123 / Q01149
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 40983221
Gene end: 41002980
  
Corresponding Affymetrix probe sets: Dr.1377.1.A1_at (Zebrafish Array)   Dr.23532.1.A1_at (Zebrafish Array)   Dr.5521.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000118091
NCBI entrez gene - 336471     See in Manteia.
swissprot - Q6IQX2
ZFIN ID - ZDB-GENE-030131-8415
Ensembl - ENSDARG00000020007
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COL1A2ENSGALG00000009641Gallus gallus
 COL1A2ENSG00000164692Homo sapiens
 Col1a2ENSMUSG00000029661Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
col2a1a / collagen, type II, alpha 1a / COL2A1* / P02458* / P28481* / collagen type II alpha 1 chain* / Collagen alpha-1(II) chain Collagen alpha-1(II) chain Chondrocalcin*ENSDARG0000006909364
col1a1b / collagen, type I, alpha 1b / COL1A1* / P02452* / P11087* / Collagen alpha-1(I) chain * / collagen type I alpha 1 chain*ENSDARG0000003580962
col1a1a / collagen, type I, alpha 1a / COL1A1* / P02452* / P11087* / Collagen alpha-1(I) chain * / collagen type I alpha 1 chain*ENSDARG0000001240562
col2a1b / collagen, type II, alpha 1b / COL2A1* / P02458* / collagen type II alpha 1 chain*ENSDARG0000001140761
col5a2a / collagen, type V, alpha 2a / COL5A2* / P05997* / Q3U962* / Collagen alpha-2(V) chain * / collagen type V alpha 2 chain*ENSDARG0000003167855
col5a2b / collagen, type V, alpha 2b / COL5A2* / P05997* / Q3U962* / Collagen alpha-2(V) chain * / collagen type V alpha 2 chain*ENSDARG0000002484752
col5a1 / procollagen, type V, alpha 1 / O88207* / P20908* / Collagen alpha-1(V) chain * / collagen type V alpha 1 chain*ENSDARG0000001259343
col11a1b / collagen, type XI, alpha 1b / Q61245* / P12107* / COL11A1* / Collagen alpha-1(XI) chain * / collagen type XI alpha 1 chain*ENSDARG0000000901443
col11a1a / collagen, type XI, alpha 1a / Q61245* / P12107* / COL11A1* / Collagen alpha-1(XI) chain * / collagen type XI alpha 1 chain*ENSDARG0000002616543
col11a2 / collagen, type XI, alpha 2 / Q64739* / P13942* / Collagen alpha-2(XI) chain * / collagen type XI alpha 2 chain*ENSDARG0000001242243
col5a3b / collagen, type V, alpha 3b / COL5A3* / P25940* / collagen, type V, alpha 3* / collagen type V alpha 3 chain*ENSDARG0000010181642
col5a3a / collagen, type V, alpha 3a / COL5A3* / P25940* / collagen, type V, alpha 3* / collagen type V alpha 3 chain*ENSDARG0000009829442
si:ch211-196i2.1ENSDARG0000000791239
si:dkey-21p1.3ENSDARG0000000229532
si:dkey-61l1.4ENSDARG0000009256732
col27a1b / collagen, type XXVII, alpha 1b / Q8IZC6* / Q5QNQ9* / COL27A1* / Collagen alpha-1(XXVII) chain * / collagen type XXVII alpha 1 chain*ENSDARG0000009993023
si:ch1073-286c18.5ENSDARG000000985671


Protein motifs (from Interpro)
Interpro ID Name
 IPR000885  Fibrillar collagen, C-terminal
 IPR008160  Collagen triple helix repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009612 response to mechanical stimulus IDA
 cellular_componentGO:0005581 collagen trimer IEA
 molecular_functionGO:0005201 extracellular matrix structural constituent IEA


Pathways (from Reactome)
Pathway description
GPVI-mediated activation cascade
Collagen degradation
Extracellular matrix organization
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Anchoring fibril formation
Crosslinking of collagen fibrils
Non-integrin membrane-ECM interactions
ECM proteoglycans
Platelet Adhesion to exposed collagen
MET activates PTK2 signaling
Collagen chain trimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001115 trunk trunk shortened , abnormal
Show

 ZFA:0001189 vertebra vertebra composition , abnormal
vertebra deformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000010085 p4ha2 / procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2 / O15460* / prolyl 4-hydroxylase subunit alpha 2*  / reaction
 ENSDARG00000033537 p4ha1a / prolyl 4-hydroxylase, alpha polypeptide I a / P4HA1* / P13674* / Q60715* / prolyl 4-hydroxylase subunit alpha 1*  / reaction
 ENSDARG00000071082 p4ha1b / prolyl 4-hydroxylase, alpha polypeptide I b / P4HA1* / P13674* / Q60715* / prolyl 4-hydroxylase subunit alpha 1*  / reaction
 ENSDARG00000020007 col1a2 / collagen, type I, alpha 2 / Q01149* / P08123* / Collagen alpha-2(I) chain * / collagen type I alpha 2 chain*  / - / reaction / complex
 ENSDARG00000105116 p4hb / prolyl 4-hydroxylase, beta polypeptide / P07237* / P09103* / prolyl 4-hydroxylase subunit beta*  / reaction / complex






 

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