ENSMUSG00000029661


Mus musculus

Features
Gene ID: ENSMUSG00000029661
  
Biological name :Col1a2
  
Synonyms : Col1a2 / Collagen alpha-2(I) chain / Q01149
  
Possible biological names infered from orthology : collagen type I alpha 2 chain / P08123
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: A1
Gene start: 4504814
Gene end: 4541544
  
Corresponding Affymetrix probe sets: 10536220 (MoGene1.0st)   1423110_at (Mouse Genome 430 2.0 Array)   1446326_at (Mouse Genome 430 2.0 Array)   1450857_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125275
Ensembl peptide - ENSMUSP00000031668
NCBI entrez gene - 12843     See in Manteia.
MGI - MGI:88468
RefSeq - NM_007743
RefSeq Peptide - NP_031769
swissprot - E0CXI2
swissprot - Q01149
swissprot - Q3TX57
Ensembl - ENSMUSG00000029661
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 col1a2ENSDARG00000020007Danio rerio
 COL1A2ENSGALG00000009641Gallus gallus
 COL1A2ENSG00000164692Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Col1a1 / P11087 / Collagen alpha-1(I) chain / P02452* / collagen type I alpha 1 chain*ENSMUSG0000000150664
Col2a1 / P28481 / Collagen alpha-1(II) chain Collagen alpha-1(II) chain Chondrocalcin / P02458* / collagen type II alpha 1 chain*ENSMUSG0000002248362
Col3a1 / P08121 / Collagen alpha-1(III) chain / P02461* / collagen type III alpha 1 chain*ENSMUSG0000002604356
Col5a2 / Q3U962 / Collagen alpha-2(V) chain / P05997* / collagen type V alpha 2 chain*ENSMUSG0000002604255
Q61245 / Col11a1 / Collagen alpha-1(XI) chain / P12107* / collagen type XI alpha 1 chain*ENSMUSG0000002796645
Col5a1 / O88207 / Collagen alpha-1(V) chain / P20908* / collagen type V alpha 1 chain*ENSMUSG0000002683745
Col5a3 / collagen, type V, alpha 3 / P25940* / collagen type V alpha 3 chain*ENSMUSG0000000409843
Q64739 / Col11a2 / Collagen alpha-2(XI) chain / P13942* / collagen type XI alpha 2 chain*ENSMUSG0000002433042
Q5QNQ9 / Col27a1 / Collagen alpha-1(XXVII) chain / Q8IZC6* / collagen type XXVII alpha 1 chain*ENSMUSG0000004567238
Q30D77 / Col24a1 / Collagen alpha-1(XXIV) chain / Q17RW2* / collagen type XXIV alpha 1 chain*ENSMUSG0000002819736


Protein motifs (from Interpro)
Interpro ID Name
 IPR000885  Fibrillar collagen, C-terminal
 IPR008160  Collagen triple helix repeat
 IPR014716  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
 IPR016133  Insect cysteine-rich antifreeze protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0001568 blood vessel development IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0007266 Rho protein signal transduction IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0030199 collagen fibril organization IEA
 biological_processGO:0043589 skin morphogenesis IEA
 biological_processGO:0070208 protein heterotrimerization IDA
 biological_processGO:0071230 cellular response to amino acid stimulus IDA
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0005584 collagen type I trimer IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0005201 extracellular matrix structural constituent IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030674 protein binding, bridging IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046332 SMAD binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048407 platelet-derived growth factor binding IEA


Pathways (from Reactome)
Pathway description
GPVI-mediated activation cascade
Collagen degradation
Extracellular matrix organization
Collagen biosynthesis and modifying enzymes
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Assembly of collagen fibrils and other multimeric structures
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Anchoring fibril formation
Crosslinking of collagen fibrils
Non-integrin membrane-ECM interactions
ECM proteoglycans
GP1b-IX-V activation signalling
Platelet Adhesion to exposed collagen
Platelet Aggregation (Plug Formation)
MET activates PTK2 signaling
Collagen chain trimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000061 fragile skeleton "easily damaged or broken bones" [J:14208]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0000062 increased bone density "increased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]
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Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (A/J x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (BALB/cByJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (C3H/HeJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (FVB/NJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1b(EUCOMM)Wtsi/Col1a2tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Col1a2tm1b(EUCOMM)Wtsi/Bay

 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0000135 reduced cortical bone thickness "thinner than normal superficial layer of compact bone " [J:61509]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (A/J x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (BALB/cByJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (C3H/HeJ x B6.129-Col1a2tm1.1Mcbr)F1

 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0000161 scoliosis "lateral and rotational curvature of the spine" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53770, J:66943]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0000550 abnormal forelimb morphology "malformation of the entire anterior extremities" [MGI:tc]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0000559 abnormal femur morphology "structural anomaly of the long bone of the thigh" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cbx2tm1b(KOMP)Wtsi/Cbx2+
Genetic Background: C57BL/6N-Cbx2tm1b(KOMP)Wtsi/H

 MP:0001243 abnormal dermal layer morphology "malformed or atypical condition of the dermal layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:56777]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Casp1tm1Flv/Casp1tm1Flv,Casp4del/Casp4del
Genetic Background: B6.129S2-Casp1tm1Flv

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (A/J x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (BALB/cByJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (C3H/HeJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (FVB/NJ x B6.129-Col1a2tm1.1Mcbr)F1

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0002060 abnormal skin morphology "malformation or atypical structure of the membranous protective covering of the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:56777]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

Allelic Composition: Col1a2oim/Col1a2oim
Genetic Background: B6C3Fe a/a-Col1a2oim/J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Skor2Tn(sb-Tyr)1799B.CA3Ove/Skor2Tn(sb-Tyr)1799B.CA3Ove
Genetic Background: involves: FVB/N

 MP:0002753 dilated left ventricle "an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Col1a2tm1b(EUCOMM)Wtsi/Col1a2tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Col1a2tm1b(EUCOMM)Wtsi/Bay

 MP:0002759 abnormal caudal vertebrae morphology "malformed bony segments of the tail, usually 27-30 present" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:82849]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0002896 abnormal bone mineralization "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0002932 abnormal joint "defect in the articulation point of two or more bones" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0003098 reduced tendon stiffness "decreased ability of tendon to maintain tensile strength and load" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, J:79915]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0003723 abnormal long bone morphology "malformation of any of the several elongated bones of the extremities " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0003797 abnormal compact bone morphology "structural anomaly of the outer layers of solid, hard bone that covers spongy bone; consists of parallel osteons containing mineral deposits and interstitial lamellae" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Qkqk-k2/Qkqk-k2
Genetic Background: involves: C57BL/6 * CBA/Ca

Allelic Composition: Col1a2oim/Col1a2oim
Genetic Background: B6C3Fe a/a-Col1a2oim/J

 MP:0004991 decreased bone strength "reduced ability of bone to endure the application of force without yielding or breaking" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Qkqk-k2/Qkqk-k2
Genetic Background: involves: C57BL/6 * CBA/Ca

Allelic Composition: Col1a2oim/Col1a2oim
Genetic Background: B6C3Fe a/a-Col1a2oim/J

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (A/J x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (BALB/cByJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (C3H/HeJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (FVB/NJ x B6.129-Col1a2tm1.1Mcbr)F1

 MP:0005503 abnormal tendon morphology "structural anomaly of the fibrous bands or cords of connective tissue at the ends of muscle fibers that attach muscles to bones and other structures" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:45509]
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Allelic Composition: Col1a2oim/Col1a2oim
Genetic Background: B6C3Fe a/a-Col1a2oim/J

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Col1a2tm1b(EUCOMM)Wtsi/Col1a2tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Col1a2tm1b(EUCOMM)Wtsi/Bay

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Col1a2tm1b(EUCOMM)Wtsi/Col1a2tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Col1a2tm1b(EUCOMM)Wtsi/Bay

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Col1a2tm1b(EUCOMM)Wtsi/Col1a2tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Col1a2tm1b(EUCOMM)Wtsi/Bay

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (A/J x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (BALB/cByJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (C3H/HeJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (FVB/NJ x B6.129-Col1a2tm1.1Mcbr)F1

 MP:0010869 decreased bone trabecula number "decreased number of intersecting plates and spicules in cancellous bone which form a meshwork of intercommunicating spaces filled with blood vessels and marrow; in mature bone, the trabeculae are aligned in parallel with the lines of major compressive or tensile force" [http://www.dorlands.com/ "Dorland s Illustrated Medical Dictionary, 31st edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (A/J x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (BALB/cByJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (C3H/HeJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (FVB/NJ x B6.129-Col1a2tm1.1Mcbr)F1

 MP:0010876 decreased bone volume "reduced amount of space occupied by bone tissue in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (A/J x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (BALB/cByJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (C3H/HeJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (FVB/NJ x B6.129-Col1a2tm1.1Mcbr)F1

 MP:0010968 decreased compact bone area "reduction in the total amount of cross-sectional area of compact bone tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (A/J x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (BALB/cByJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (C3H/HeJ x B6.129-Col1a2tm1.1Mcbr)F1

 MP:0010970 abnormal compact bone lamellar structure "any structural anomaly of the concentric layers of calcified matrix interspersed with osteocytes lodged in lacunae between the lamellae that comprise the cylindrical osteons" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

Allelic Composition: Col1a2oim/Col1a2oim
Genetic Background: B6C3Fe a/a-Col1a2oim/J

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Casp1tm1Flv/Casp1tm1Flv,Casp4del/Casp4del
Genetic Background: B6.129S2-Casp1tm1Flv

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Casp1tm1Flv/Casp1tm1Flv,Casp4del/Casp4del
Genetic Background: B6.129S2-Casp1tm1Flv

 MP:0011505 camptomelia "a skeletal dysplasia characterized by the bending of the long bones of the extremities" [ISBN:0-683-40008-8]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0013615 increased volumetric bone mineral density "increase in the mineral mass per unit volume of bone, the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts; this is expressed as the amount of mineral per cubic cm of bone (usually in mgHA/cm^3), with results generated from Quantitative computed tomography (QCT) and other tests" [PMID:12730800, PMID:17481978]
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Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (A/J x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (BALB/cByJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (C3H/HeJ x B6.129-Col1a2tm1.1Mcbr)F1

Allelic Composition: Col1a2tm1.1Mcbr/Col1a2+
Genetic Background: (FVB/NJ x B6.129-Col1a2tm1.1Mcbr)F1

 MP:0030482 increased osteocyte number "greater than average number of mature osteoblasts that have become embedded in the bone matrix (osteoid) in small cavities called lacunae and that extend cytoplasmic (dendritic) processes away from the cell body toward other osteocytes and neighboring cells in small channels called canaliculi" [MGI:anna]
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Allelic Composition: Bmp4tm2Blh/Bmp4+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000001506 Col1a1 / P11087 / Collagen alpha-1(I) chain / P02452* / collagen type I alpha 1 chain*  / complex / reaction / -
 ENSMUSG00000019916 P4ha1 / Q60715 / Prolyl 4-hydroxylase subunit alpha-1 / P13674*  / reaction
 ENSMUSG00000018906 P4ha2 / Q60716 / Prolyl 4-hydroxylase subunit alpha-2 / O15460*  / reaction
 ENSMUSG00000025130 P4hb / P09103 / prolyl 4-hydroxylase, beta polypeptide / P07237* / prolyl 4-hydroxylase subunit beta*  / complex / reaction
 ENSMUSG00000029661 Col1a2 / Q01149 / Collagen alpha-2(I) chain / P08123* / collagen type I alpha 2 chain*  / - / complex / reaction
 ENSMUSG00000051048 P4ha3 / prolyl 4-hydroxylase subunit alpha 3 / Q7Z4N8*  / reaction






 

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