| MP:0000063 | reduced bone density | "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0000065 | abnormal bone marrow cavities | "absence or abnormal size or shape of the medullary cavities of the bones" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
|
| MP:0000074 | abnormal neurocranium morphology | "malformed bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
Show
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
|
| MP:0000088 | short mandible | "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0000103 | nasal bone hypoplasia | "reduced cell number in the bone which forms the nasal bridge" [J:53370] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0000111 | cleft palate | "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1M2J/Col2a1+
Genetic Background: B6;C3Fe-Col2a1M2J/GrsrJ
Allelic Composition: Col2a1Lpk/Col2a1Lpk
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0000130 | abnormal cancellous bone morphology | "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0000131 | abnormal long bone epiphysis morphology | "the head of a developing long bone that is separated from the shaft by the epiphyseal plate" [J:61509] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0000133 | abnormal long bone metaphysis morphology | "malformed conical section of bone between the epiphysis and diaphysis of the long bones" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61295] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0000137 | abnormal vertebrae morphology | "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
Allelic Composition: Col2a1Rgsc856/Col2a1Rgsc856
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0000141 | abnormal vertebral body morphology | "malformed main portion of the vertebra anterior to the vertebral canal" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0000149 | abnormal scapula morphology | "malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049] |
Show
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0000150 | abnormal rib morphology | "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0000163 | abnormal cartilage morphology | "anomalous structure or development of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: AqrGt(PT1-ATG)193Wrst/AqrGt(PT1-ATG)193Wrst
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1Lpk/Col2a1Lpk
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0000164 | abnormal cartilage development | "anomalous formation of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1Lpk/Col2a1Lpk
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0000165 | abnormal hypertrophic chondrocyte zone | "anomaly of the cartilage cell matrix layer " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0000166 | abnormal chondrocyte morphology | "anomalous structure, organization, or differentiation of nondividing cartilage cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Rgsc856/Col2a1Rgsc856
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1Lpk/Col2a1Lpk
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0000285 | abnormal cardiac valve morphology | "malformation of the membranous folds of the heart that prevent reflux of fluid" [J:18048] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
|
| MP:0000432 | abnormal head morphology | "anomalous structure or development of the portion of the body containing the brain and organs of sight, hearing, taste, and smell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Acetm1Keb/Acetm1Keb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Col2a1tm1.1Ksec/Col2a1+
Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec,Nodaltm1Rob/Nodal+
Genetic Background: involves: 129S/SvEv * 129X1/SvJ * C57BL/6
Allelic Composition: Col2a1tm1.1Ksec/Col2a1+,Nodaltm1Rob/Nodal+
Genetic Background: involves: 129S/SvEv * 129X1/SvJ * C57BL/6
|
| MP:0000433 | microcephaly | "an abnormally small head" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Acetm1Keb/Acetm1Keb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Col2a1tm1.1Ksec/Col2a1+
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Bmpr1atm1Bhr/Bmpr1a+,Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0000435 | shortened head | "reduced anterior-posterior length of the head" [J:42035] |
Show
Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H
|
| MP:0000438 | abnormal skull morphology | "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0000440 | domed skull | |
Show
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0000443 | abnormal snout morphology | "anomalous structure or development of the anterior facial part of the muzzle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Acetm1Keb/Acetm1Keb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0000445 | short snout | "reduced length of the anterior facial part of the muzzle" [J:53370] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Col2a1Rgsc856/Col2a1Rgsc856
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1M2J/Col2a1+
Genetic Background: B6;C3Fe-Col2a1M2J/GrsrJ
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1M3J/Col2a1+
Genetic Background: B6(Cg)-Col2a1M3J/GrsrJ
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Col2a1Rgsc413/Col2a1Rgsc413
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0000457 | maxilla hypoplasia | "arrested growth or atrophy of the upper bony framework of the mouth where the superior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0000533 | kidney hemorrhage | "bleeding in the organ of excretion" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
|
| MP:0000547 | short limbs | "reduced average length of the extremities" [MGI:CLS, J:61509] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1Rgsc413/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: either: C3H.Cg-Col2a1Lpk/H or (involves: C3H/HeH * C57BL/6J)
Allelic Composition: Col2a1Rgsc856/Col2a1Rgsc856
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
Allelic Composition: Col2a1Rgsc413/Col2a1Rgsc413
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0000550 | abnormal forelimb morphology | "malformation of the entire anterior extremities" [MGI:tc] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0000556 | abnormal hindlimb morphology | "malformation of the entire posterior extremities" [MGI:tc] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0000572 | abnormal autopod morphology | "malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
|
| MP:0000783 | abnormal forebrain morphology | "malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0000830 | abnormal diencephalon morphology | "any malformation or absence of the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0000913 | abnormal brain development | "malformed or incomplete differentiation of the brain" [MGI:cls, J:49840] |
Show
Allelic Composition: Acetm1Keb/Acetm1Keb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0001081 | abnormal cranial ganglia morphology | "any anomaly, deformity, or malformation of the groups of nerve cell bodies associated with the twelve cranial nerves" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:45302] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0001178 | pulmonary hypoplasia | "reduced size of the respiratory organ due to incomplete development of all or part of the organ " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
Show
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
|
| MP:0001258 | decreased body length | "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0001260 | increased body weight | "greater than normal average weight " [J:33400] |
Show
Allelic Composition: Col2a1M2J/Col2a1+
Genetic Background: B6;C3Fe-Col2a1M2J/GrsrJ
|
| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
Show
Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+,Sox9tm1Crm/Sox9+
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Col2a1Rgsc413/Col2a1Rgsc413
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0001270 | distended abdomen | "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0001286 | abnormal eye development | "malformation or arrest of differentiation of the visual organ" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:49840] |
Show
Allelic Composition: Acetm1Keb/Acetm1Keb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0001303 | abnormal lens morphology | "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0001328 | disorganized retinal layers | "delaminated or mispositioned sheets of cells comprising the optic part of the retina" [J:33400] |
Show
Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ
|
| MP:0001410 | head bobbing | "compulsive up and down movement of the head" [J:17123] |
Show
Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ
|
| MP:0001411 | spinning | "compulsive rolling of the body" [J:17123] |
Show
Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ
|
| MP:0001533 | abnormal skeleton physiology | "anomalous function of the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Relatm1Rsch/Relatm1Rsch,Tg(Cd4-cre)1Cwi/0
Genetic Background: involves: C57BL/6 * DBA/2
|
| MP:0001575 | cyanosis | "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159] |
Show
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0001663 | abnormal digestive system physiology | "altered function of the organ system that converts ingested food to nutrients and energy" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ
|
| MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0001942 | abnormal lung volume | "anomaly in the amount of air that the lungs contain at various points of the respiratory cycle" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
|
| MP:0001954 | respiratory distress | "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0002064 | seizures | "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ
|
| MP:0002089 | abnormal postnatal growth/weight/body size | "increased or decreased average body size, weight or growth characteristic abnormalities manifesting after birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H
|
| MP:0002109 | abnormal limb morphology | "abnormal development of limbs resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Scn8am11J/Scn8am11J
Genetic Background: B6.Cg-Scn8am11J/GrsrJ
|
| MP:0002111 | abnormal tail morphology | "abnormal development of the tail resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1+
Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Bmpr1atm1Bhr/Bmpr1a+,Col2a1tm1.1Ksec/Col2a1+
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
|
| MP:0002113 | abnormal skeleton development | "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+,Sox9tm1Crm/Sox9+
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0002114 | abnormal axial skeleton morphology | "abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
|
| MP:0002115 | abnormal skeleton extremities morphology | "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
|
| MP:0002116 | abnormal craniofacial bone morphology | "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
|
| MP:0002151 | abnormal neural tube morphology/development | "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Bmpr1atm1Bhr/Bmpr1a+,Col2a1tm1.1Ksec/Col2a1+
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
|
| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: PhexMhdabap024/PhexMhdabap024
Genetic Background: C3HeB/FeJ-PhexMhdabap024
Allelic Composition: Col2a1tm1Dshh/Col2a1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0002270 | abnormal alveoli morphology | "any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
|
| MP:0002427 | dwarfism | "abnormally undersized with disproportionate body parts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0002544 | brachydactyly | "abnormally short digits" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1Rgsc856
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0002657 | chondrodystrophy | "abnormal development of the cartilage primordia of long bones, resulting in abnormally short extremities but normal head and trunk" [il:Ira Lu , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0002764 | short tibia | " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0002765 | short fibula | "reduced length of the lateral and smaller of bone of the lower leg" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:12736] |
Show
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0002932 | abnormal joint | "defect in the articulation point of two or more bones" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0003055 | abnormal epiphyseal plate morphology | "malformed or absent cartilagenous center of ossification on the long bones permitting growth of the bone in both directions during development" [MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
Show
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0003056 | abnormal hyoid bone | "anomalous structure of the U-shaped bone lying between the mandible and the larynx that supports the tongue muscles" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
|
| MP:0003109 | short femur | "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0003232 | abnormal forebrain development | "anomaly in the formation or patterning of the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [J:93081, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1+
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0003409 | decreased width of hypertrophic chondrocyte zone | "decreased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0003419 | delayed endochondral bone ossification | "late onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631] |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0003425 | abnormal optic vesicle formation | "anomalous formation of the hollow outgrowth from the lateral aspects of the embryonic forebrain from which the retina and optic nerve develop" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94391] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0003560 | osteoarthritis | "a type of arthritis that is caused by the breakdown and eventual loss of the cartilage of one or more joints" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95374] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1+,Col9a1tm1Jae/Col9a1tm1Jae
Genetic Background: involves: 129/Sv * 129S2/SvPas
|
| MP:0003662 | abnormal proliferative zone | "germinal layer of the epiphyseal plate where cells are actively dividing as well as producing extracellular matrix" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96254] |
Show
Allelic Composition: Col2a1Rgsc413/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Rgsc856/Col2a1Rgsc856
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Lpk/Col2a1Lpk
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Col2a1Rgsc413/Col2a1Rgsc413
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0003723 | abnormal long bone morphology | "malformation of any of the several elongated bones of the extremities
" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0003795 | abnormal bone structure | |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0004134 | abnormal chest morphology | "malformation of the part of the body between the neck and the abdomen " [smb:Susan M Bello, Mouse Genome Informatics Curator, J:59168] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0004148 | increased cortical bone thickness | "thicker than normal superficial layer of compact bone" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0004200 | reduced fetal size | "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Rgsc856/Col2a1Rgsc856
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Lpk/Col2a1Lpk
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0004282 | retrognathia | "abnormal posterior positioning of one or both jaws, particularly the mandible, relative to the facial skeleton and soft tissues" [J:41682, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0004351 | short humerus | "reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0004355 | short radius | "reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0004356 | radius hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, in the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
|
| MP:0004359 | short ulna | "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0004471 | short nasal bone | "reduced length of either of two rectangular bone plates forming the bridge of the nose" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0004509 | abnormal pelvic girdle bone morphology | "any structural anomaly of the bones of the pelvis by which the limbs attach to the axial skeleton " [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1Rgsc856
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Col2a1Rgsc413/Col2a1Rgsc413
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0004599 | abnormal vertebral arch morphology | "any structural anomaly of the dorsal part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
|
| MP:0004624 | abnormal thoracic cage | "any structural anomaly of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0004667 | vertebral body hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0004669 | enlarged vertebral body | "increased size of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0004672 | short ribs | "reduced length of the bones forming the bony wall of the chest" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
|
| MP:0004683 | absent intervertebral disk | "absence of the cartilaginous and gelatinous structure found between vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0004686 | decreased length of long bones | "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1Lpk/Col2a1Lpk
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0004704 | short vertebral column | "decreased rostral-caudal length of the complete structure forming the rostral-caudal axis of the skeleton formed from the alternating segments of vertebra and intervertebral discs which support the spinal cord" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
|
| MP:0004708 | short lumbar vertebrae | "reduced length of any or all of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0004711 | persistence of notochord tissue | "failure of notochord tissue to differentiate into the vertebral primordia during development resulting in the presence of notochord tissue at later stages than it is normally seen" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0004871 | premaxilla hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, in the anterior and interior portion of the maxilla" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0004872 | absent nasal septum | "absence of the structure that separates the two nasal cavities" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0005108 | abnormal ulna morphology | "malformation of the medial and larger of the two bones of the forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132] |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0005157 | holoprosencephaly | "presence of a single forebrain hemisphere or lobe; often accompanied by a deficit in median facial development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83058] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0005163 | cyclopia | "a congenital defect in which the two orbits are united to form a single cavity containing one eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60303] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Col2a1tm1.1Ksec/Col2a1+
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Bmpr1atm1Bhr/Bmpr1a+,Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
|
| MP:0005193 | abnormal anterior eye segment morphology | "anomalous structure of any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0005195 | abnormal posterior eye segment morphology | "anomalous structure of any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0005225 | abnormal vertebrae development | "anomalous formation of the vertebrae from the sclerotome" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0005306 | abnormal phalanx morphology | "aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0005352 | small skull | "less than the normal size of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
|
| MP:0005458 | increased percent body fat | "more fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Col2a1M2J/Col2a1+
Genetic Background: B6;C3Fe-Col2a1M2J/GrsrJ
|
| MP:0005459 | decreased percent body fat | "less fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Col2a1M2J/Col2a1+
Genetic Background: B6;C3Fe-Col2a1M2J/GrsrJ
|
| MP:0005508 | abnormal skeleton morphology | "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1Rgsc856
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: C.B6(C3)-Col2a1Lpk
|
| MP:0005525 | increased renal plasma flow rate | "greater than the normal volume of plasma passing throught the kidney per unit time" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
|
| MP:0006198 | enophthalmos | "sinking or retraction of the eye back into the socket" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Col2a1tm1.1Ksec/Col2a1+
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Bmpr1atm1Bhr/Bmpr1a+,Col2a1tm1.1Ksec/Col2a1+
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
|
| MP:0006290 | proboscis | "a long, cylindric protuberance of the face that, in cyclopia or ethmocephaly, represents the nose" [J:92058, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0006325 | impaired hearing | "reduced ability to percieve auditory stimuli" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ush1cdfcr/Ush1cdfcr
Genetic Background: involves: BALB/cByJ
|
| MP:0006395 | abnormal epiphyseal plate morphology | "any structural anomaly of the cartilaginous center of ossification on the bones permitting growth of the bone in both directions during development" [MESH:A02.835.232.251.352] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Rgsc856/Col2a1Rgsc856
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0006397 | disorganized long bone epiphyseal plate | "a lack of the regular arrangement of the cells or zones of the epiphyseal plate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1Rgsc413/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1Lpk/Col2a1Lpk
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Col2a1Rgsc413/Col2a1Rgsc413
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0006398 | increased long bone epiphyseal plate size | "greater than the normal size of the cartilaginous center of ossification on the long bones permitting growth of the bone in both directions during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0006399 | abnormal long bone epiphyseal ossification zone morphology | "any anomaly in the structure of the layer of the epiphyseal plate where new bone matrix is deposited" [CALnet tutorial:http://137.222.110.150/calnet/Introanat/Introanat.htm, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0006433 | abnormal articular cartilage morphology | "any structural anomaly of the thin layer of smooth hyaline cartilage located on the joint surfaces of a bone" [ISBN:0-8036-0655-9 "Taber s Cyclopedic Medical Dictionary", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
|
| MP:0008069 | abnormal joint mobility | "anomaly in the ability to move joints in a full range of motion and with ease" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0008151 | increased diameter of long bones | "increased width of the cross-sectional distance that extends from one lateral edge of a long bone, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1Lpk/Col2a1Lpk
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0008158 | increased diameter of femur | "increased width of the cross-sectional distance that extends from one lateral edge of the femur, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0008159 | increased diameter of fibula | "increased width of the cross-sectional distance that extends from one lateral edge of the fibula, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0008160 | increased diameter of humerus | "increased width of the cross-sectional distance that extends from one lateral edge of the humerus, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0008161 | increased diameter of radius | "increased width of the cross-sectional distance that extends from one lateral edge of the radius, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0008162 | increased diameter of tibia | "increased width of the cross-sectional distance that extends from one lateral edge of the tibia, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0008163 | increased diameter of ulna | "increased width of the cross-sectional distance that extends from one lateral edge of the ulna, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0008271 | abnormal bone ossification | "any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503] |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0008272 | abnormal endochondral bone ossification | "anomaly in the process of the formation of bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0008736 | micromelia | "disproportionately short or small limbs" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0009266 | abnormal mesendoderm development | "failure or abnormality in the formation of the embryonic cell layer that gives rise to both the endoderm and mesoderm" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Col2a1tm1.1Ksec/Col2a1+
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0009780 | abnormal chondrocyte physiology | "any functional anomaly of nondividing cartilage cells" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Rgsc856/Col2a1Rgsc856
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0009882 | absent palatal shelf | "absence of the palatal projections from the inner part of the maxillary processes that fuse to form the secondary palate" [PMID:16680722] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
|
| MP:0009890 | cleft secondary palate | "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722] |
Show
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
|
| MP:0010029 | abnormal basicranium morphology | "any structural anomaly of the sloping floor of the cranial cavity that is comprised of parts of the ethmoidal, occipital and sphenoid bones" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
|
| MP:0010103 | small thoracic cage | "reduced size of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
|
| MP:0010869 | decreased bone trabecula number | "decreased number of intersecting plates and spicules in cancellous bone which form a meshwork of intercommunicating spaces filled with blood vessels and marrow; in mature bone, the trabeculae are aligned in parallel with the lines of major compressive or tensile force" [http://www.dorlands.com/ "Dorland s Illustrated Medical Dictionary, 31st edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0010876 | decreased bone volume | "reduced amount of space occupied by bone tissue in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0010879 | decreased trabecular bone volume | "decrease in the amount of space occupied by trabecular bone tissue in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
|
| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
Show
Allelic Composition: Col2a1Dmm/Col2a1+
Genetic Background: involves: 101 * C3H
|
| MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
Show
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0011088 | partial neonatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+,Sox9tm1Crm/Sox9+
Genetic Background: involves: 129S4/SvJae
|
| MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1Rgsc856/Col2a1Rgsc856
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Lpk/Col2a1Lpk
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1Rgsc413/Col2a1Rgsc413
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
Show
Allelic Composition: Col2a1Dmm/Col2a1Dmm
Genetic Background: involves: 101 * C3H
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Bmpr1atm1Bhr/Bmpr1a+,Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
|
| MP:0011175 | platyspondylia | "flatness of the bodies of the vertebrae; one or many vertebrae may be affected" [ISBN:0-683-40008-8] |
Show
Allelic Composition: Col2a1Rgsc856/Col2a1Rgsc856
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Col2a1Rgsc413/Col2a1Rgsc413
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0011495 | abnormal head shape | "any anomaly in the characteristic surface outline or contour of a head of an organism" [MGI:csmith] |
Show
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0011504 | abnormal limb long bone morphology | |
Show
Allelic Composition: Col2a1Lpk/Col2a1+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: Col2a1mc13/Col2a1mc13
Genetic Background: involves: C57BL/6J * FVB/NJ
|
| MP:0011812 | increased cranium length | "having an increased dorsal-to-ventral distance of the cranium" [MGI:mberry] |
Show
Allelic Composition: Col2a1M2J/Col2a1+
Genetic Background: B6;C3Fe-Col2a1M2J/GrsrJ
|
| MP:0012085 | midface hypoplasia | "underdevelopment of the midfacial region comprising the nasal, maxillary, and zygomatic bones, leading to a concave-looking face" [MGI:anna] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1+
Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Col2a1tm1.1Ksec/Col2a1+
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Bmpr1atm1Bhr/Bmpr1a+,Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
|
| MP:0013817 | absent nasal cavity | "absence of the cavity of the respiratory tract that extends from the nares to the pharynx; the nasal cavity is lined with ciliated mucosa" [MESH:A04.531.449] |
Show
Allelic Composition: Col2a1tm1.1Ksec/Col2a1tm1.1Ksec
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0014101 | decreased chondrocyte proliferation | "decreased amount of multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population" [GO:0035988] |
Show
Allelic Composition: Col2a1tm1(SOX9)Crm/Col2a1+
Genetic Background: 129S/Sv-Col2a1tm1(SOX9)Crm
|
| MP:0014103 | increased chondrocyte apoptosis | "increased number of chondrocytes undergoing programmed cell death" [MGI:csmith] |
Show
Allelic Composition: Col2a1Rgsc413/Col2a1Rgsc413
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0014164 | abnormal ciliary process morphology | " any structural anomaly of any of the pigmented processes that radiate from the ciliary muscle and give attachments to ligaments supporting the lens of the eye; these processes increase in thickness as they advance from the orbiculus ciliaris to the external border of the iris, and together with the folds (plicae) in the furrows between them, constitute the corona ciliaris; ciliary processes produce aqueous humor" [http://www.medilexicon.com/medicaldictionary.php?s=processus+ciliaris] |
Show
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0030049 | prominent forehead | "forward prominence of the entire forehead, due to protrusion of the frontal bone; not to be confused with frontal bossing" [HP:0011220] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1tm1Prc/Col2a1+
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0030384 | short facial bone | "length reduction or truncation of one or more facial bones" [MGI:anna] |
Show
Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Tg(KRT5-cre)5132Jlj/0,Tg(KRT5-E2F1)2Dgj/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Col2a1tm1Prc/Col2a1tm1Prc
Genetic Background: involves: 129/Sv
Allelic Composition: Col2a1tm1Dshh/Col2a1tm1Dshh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
