ENSDARG00000038990


Danio rerio

Features
Gene ID: ENSDARG00000038990
  
Biological name :wnt3
  
Synonyms : wingless-type MMTV integration site family, member 3 / wnt3
  
Possible biological names infered from orthology : P17553 / P56703 / Wnt family member 3
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 22258962
Gene end: 22304841
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000105032
NCBI entrez gene - 569420     See in Manteia.
RefSeq - NM_001114552
RefSeq Peptide - NP_001108024
swissprot - B0LK22
ZFIN ID - ZDB-GENE-081003-1
Ensembl - ENSDARG00000038990
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WNT3ENSGALG00000001079Gallus gallus
 WNT3ENSG00000108379Homo sapiens
 Wnt3ENSMUSG00000000125Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wnt3a / wingless-type MMTV integration site family, member 3A / P56704* / Wnt family member 3A*ENSDARG0000005882283
wnt7ba / wingless-type MMTV integration site family, member 7Ba / WNT7B* / P56706* / P28047* / Wnt family member 7B* / wingless-type MMTV integration site family, member 7B*ENSDARG0000002285844
wnt7bb / wingless-type MMTV integration site family, member 7Bb / WNT7B* / P56706* / P28047* / Wnt family member 7B* / wingless-type MMTV integration site family, member 7B*ENSDARG0000007110744
wnt1 / P24257 / wingless-type MMTV integration site family, member 1 / P04628* / P04426* / Wnt family member 1*ENSDARG0000005555444
wnt5b / Q92050 / wingless-type MMTV integration site family, member 5b / Q9H1J7* / P22726* / Wnt family member 5B*ENSDARG0000010246443
wnt4a / P47793 / wingless-type MMTV integration site family, member 4a / WNT4* / P56705* / P22724* / Wnt family member 4* / wingless-type MMTV integration site family, member 4*ENSDARG0000007120843
wnt5a / wingless-type MMTV integration site family, member 5a / P41221* / Wnt family member 5A*ENSDARG0000010497343
wnt7aa / wingless-type MMTV integration site family, member 7Aa / WNT7A* / P24383* / O00755* / Wnt family member 7A* / wingless-type MMTV integration site family, member 7A*ENSDARG0000004482742
wnt2ba / wingless-type MMTV integration site family, member 2Ba / WNT2B* / Q93097* / Wnt family member 2B*ENSDARG0000000505041
wnt7ab / wingless-type MMTV integration site family, member 7Ab / WNT7A* / O00755* / Wnt family member 7A*ENSDARG0000000248341
wnt2 / Q92048 / wingless-type MMTV integration site family member 2 / P21552* / P09544* / Wnt family member 2*ENSDARG0000004111741
wnt4b / wingless-type MMTV integration site family, member 4bENSDARG0000004015941
wnt2bb / wingless-type MMTV integration site family, member 2Bb / WNT2B* / Q93097* / O70283* / Wnt family member 2B* / wingless-type MMTV integration site family, member 2B*ENSDARG0000003223441
wnt6b / wingless-type MMTV integration site family, member 6b / WNT6* / Q9Y6F9* / P22727* / Wnt family member 6* / wingless-type MMTV integration site family, member 6*ENSDARG0000007393540
wnt16 / wingless-type MMTV integration site family, member 16 / Q9QYS1* / Q9UBV4* / Wnt family member 16*ENSDARG0000009497340
wnt11 / wingless-type MMTV integration site family, member 11ENSDARG0000000425635
wnt11r / wingless-type MMTV integration site family, member 11, related / WNT11* / P48615* / O96014* / Wnt family member 11* / wingless-type MMTV integration site family, member 11*ENSDARG0000001479635
wnt6a / wingless-type MMTV integration site family, member 6aENSDARG0000003828335


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR009141  Wnt-3 protein
 IPR018161  Wnt protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0021794 thalamus development IGI
 biological_processGO:0030182 neuron differentiation IBA
 biological_processGO:0035844 cloaca development IMP
 biological_processGO:0045165 cell fate commitment IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IBA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain malformed , abnormal
Show

 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary cellular quality , abnormal
Show

 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
Show

 ZFA:0000101 diencephalon diencephalon lacks all parts of type mid diencephalic organizer , abnormal
Show

 ZFA:0000151 pronephros pronephros distal region disorganized , abnormal
Show

 ZFA:0000330 cloacal chamber cloacal chamber distended , abnormal
Show

 ZFA:0000458 ventral thalamus ventral thalamus in contact with dorsal thalamus , abnormal
ventral thalamus decreased thickness , abnormal
Show

 ZFA:0000653 dorsal thalamus dorsal thalamus decreased thickness , abnormal
Show

 ZFA:0000706 posterior intestine posterior intestine distended , abnormal
Show

 ZFA:0001117 post-vent region post-vent region kinked , abnormal
Show

 ZFA:0005757 mid diencephalic organizer mid diencephalic organizer increased thickness , abnormal
mid diencephalic organizer decreased thickness , abnormal
mid diencephalic organizer cellular quality , abnormal
mid diencephalic organizer decreased size , abnormal
mid diencephalic organizer apoptotic , abnormal
Show

 ZFA:0005781 cloaca cloaca increased width , abnormal
cloaca cell disconnected , abnormal
cloaca epithelium disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr