ENSDARG00000041117


Danio rerio

Features
Gene ID: ENSDARG00000041117
  
Biological name :wnt2
  
Synonyms : Q92048 / wingless-type MMTV integration site family member 2 / wnt2
  
Possible biological names infered from orthology : P09544 / P21552 / Wnt family member 2
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 20613241
Gene end: 20636549
  
Corresponding Affymetrix probe sets: Dr.378.1.S1_at (Zebrafish Array)   NM_130950_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000060258
NCBI entrez gene - 30127     See in Manteia.
RefSeq - NM_130950
RefSeq Peptide - NP_571025
swissprot - Q92048
ZFIN ID - ZDB-GENE-980526-416
Ensembl - ENSDARG00000041117
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WNT2ENSGALG00000030173Gallus gallus
 WNT2ENSG00000105989Homo sapiens
 Wnt2ENSMUSG00000010797Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wnt2ba / wingless-type MMTV integration site family, member 2Ba / WNT2B* / Q93097* / Wnt family member 2B*ENSDARG0000000505067
wnt2bb / wingless-type MMTV integration site family, member 2Bb / WNT2B* / Q93097* / O70283* / Wnt family member 2B* / wingless-type MMTV integration site family, member 2B*ENSDARG0000003223465
wnt5b / Q92050 / wingless-type MMTV integration site family, member 5b / Q9H1J7* / P22726* / Wnt family member 5B*ENSDARG0000010246444
wnt5a / wingless-type MMTV integration site family, member 5a / P41221* / Wnt family member 5A*ENSDARG0000010497343
wnt7ab / wingless-type MMTV integration site family, member 7Ab / WNT7A* / O00755* / Wnt family member 7A*ENSDARG0000000248343
wnt7bb / wingless-type MMTV integration site family, member 7Bb / WNT7B* / P56706* / P28047* / Wnt family member 7B* / wingless-type MMTV integration site family, member 7B*ENSDARG0000007110743
wnt3a / wingless-type MMTV integration site family, member 3A / P56704* / Wnt family member 3A*ENSDARG0000005882243
wnt7ba / wingless-type MMTV integration site family, member 7Ba / WNT7B* / P56706* / P28047* / Wnt family member 7B* / wingless-type MMTV integration site family, member 7B*ENSDARG0000002285842
wnt3 / wingless-type MMTV integration site family, member 3 / P17553* / P56703* / Wnt family member 3*ENSDARG0000003899042
wnt4a / P47793 / wingless-type MMTV integration site family, member 4a / WNT4* / P56705* / P22724* / Wnt family member 4* / wingless-type MMTV integration site family, member 4*ENSDARG0000007120842
wnt4b / wingless-type MMTV integration site family, member 4bENSDARG0000004015941
wnt7aa / wingless-type MMTV integration site family, member 7Aa / WNT7A* / P24383* / O00755* / Wnt family member 7A* / wingless-type MMTV integration site family, member 7A*ENSDARG0000004482741
wnt1 / P24257 / wingless-type MMTV integration site family, member 1 / P04628* / P04426* / Wnt family member 1*ENSDARG0000005555440
wnt16 / wingless-type MMTV integration site family, member 16 / Q9QYS1* / Q9UBV4* / Wnt family member 16*ENSDARG0000009497338
wnt6b / wingless-type MMTV integration site family, member 6b / WNT6* / Q9Y6F9* / P22727* / Wnt family member 6* / wingless-type MMTV integration site family, member 6*ENSDARG0000007393537
wnt6a / wingless-type MMTV integration site family, member 6aENSDARG0000003828336
wnt11r / wingless-type MMTV integration site family, member 11, related / WNT11* / P48615* / O96014* / Wnt family member 11* / wingless-type MMTV integration site family, member 11*ENSDARG0000001479635
wnt11 / wingless-type MMTV integration site family, member 11ENSDARG0000000425632


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR009140  Wnt-2 protein
 IPR018161  Wnt protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IMP
 biological_processGO:0007275 multicellular organism development ISS
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0030182 neuron differentiation IBA
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0048794 swim bladder development IMP
 biological_processGO:0072574 hepatocyte proliferation IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IBA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000076 swim bladder swim bladder decreased size , abnormal
swim bladder absent , abnormal
Show

 ZFA:0000123 liver liver decreased size , abnormal
liver hypoplastic , abnormal
liver absent , abnormal
Show

 ZFA:0000208 gall bladder gall bladder absent , abnormal
gall bladder decreased size , abnormal
Show

 ZFA:0005170 extrahepatic duct extrahepatic duct decreased size , abnormal
extrahepatic duct absent , abnormal
Show

 ZFA:0009102 pancreatic B cell pancreatic B cell mislocalised , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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