ENSDARG00000104973


Danio rerio

Features
Gene ID: ENSDARG00000104973
  
Biological name :wnt5a
  
Synonyms : wingless-type MMTV integration site family, member 5a / wnt5a
  
Possible biological names infered from orthology : P22725 / P41221 / Wnt family member 5A
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 53670395
Gene end: 53680653
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000137200
swissprot - F1Q8M2
ZFIN ID - ZDB-GENE-060328-3
Ensembl - ENSDARG00000104973
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WNT5AENSGALG00000034168Gallus gallus
 WNT5AENSG00000114251Homo sapiens
 Wnt5aENSMUSG00000021994Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wnt5b / Q92050 / wingless-type MMTV integration site family, member 5b / Q9H1J7* / P22726* / Wnt family member 5B*ENSDARG0000010246471
wnt2ba / wingless-type MMTV integration site family, member 2Ba / WNT2B* / Q93097* / Wnt family member 2B*ENSDARG0000000505045
wnt4a / P47793 / wingless-type MMTV integration site family, member 4a / WNT4* / P56705* / P22724* / Wnt family member 4* / wingless-type MMTV integration site family, member 4*ENSDARG0000007120844
wnt3a / wingless-type MMTV integration site family, member 3A / P56704* / Wnt family member 3A*ENSDARG0000005882243
wnt2bb / wingless-type MMTV integration site family, member 2Bb / WNT2B* / Q93097* / O70283* / Wnt family member 2B* / wingless-type MMTV integration site family, member 2B*ENSDARG0000003223443
wnt4b / wingless-type MMTV integration site family, member 4bENSDARG0000004015942
wnt3 / wingless-type MMTV integration site family, member 3 / P17553* / P56703* / Wnt family member 3*ENSDARG0000003899041
wnt7bb / wingless-type MMTV integration site family, member 7Bb / WNT7B* / P56706* / P28047* / Wnt family member 7B* / wingless-type MMTV integration site family, member 7B*ENSDARG0000007110741
wnt7ab / wingless-type MMTV integration site family, member 7Ab / WNT7A* / O00755* / Wnt family member 7A*ENSDARG0000000248340
wnt2 / Q92048 / wingless-type MMTV integration site family member 2 / P21552* / P09544* / Wnt family member 2*ENSDARG0000004111740
wnt7ba / wingless-type MMTV integration site family, member 7Ba / WNT7B* / P56706* / P28047* / Wnt family member 7B* / wingless-type MMTV integration site family, member 7B*ENSDARG0000002285840
wnt7aa / wingless-type MMTV integration site family, member 7Aa / WNT7A* / P24383* / O00755* / Wnt family member 7A* / wingless-type MMTV integration site family, member 7A*ENSDARG0000004482740
wnt1 / P24257 / wingless-type MMTV integration site family, member 1 / P04628* / P04426* / Wnt family member 1*ENSDARG0000005555439
wnt11r / wingless-type MMTV integration site family, member 11, related / WNT11* / P48615* / O96014* / Wnt family member 11* / wingless-type MMTV integration site family, member 11*ENSDARG0000001479639
wnt11 / wingless-type MMTV integration site family, member 11ENSDARG0000000425638
wnt6b / wingless-type MMTV integration site family, member 6b / WNT6* / Q9Y6F9* / P22727* / Wnt family member 6* / wingless-type MMTV integration site family, member 6*ENSDARG0000007393537
wnt16 / wingless-type MMTV integration site family, member 16 / Q9QYS1* / Q9UBV4* / Wnt family member 16*ENSDARG0000009497336
wnt6a / wingless-type MMTV integration site family, member 6aENSDARG0000003828335


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR018161  Wnt protein, conserved site
 IPR026538  Wnt-5a protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0030182 neuron differentiation IBA
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0048793 pronephros development IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IBA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking
Ca2+ pathway
PCP/CE pathway
Asymmetric localization of PCP proteins
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct dilated , abnormal
pronephric duct cystic , abnormal
Show

 ZFA:0000151 pronephros pronephros cilium disorganized , abnormal
Show

 ZFA:0001094 whole organism whole organism anatomical axis morphology , abnormal
whole organism anatomical axis decreased length , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
post-vent region increased curvature , abnormal
Show

 ZFA:0001287 renal tubule renal tubule dilated , abnormal
Show

 ZFA:0001557 pronephric glomerulus pronephric glomerulus morphology , abnormal
pronephric glomerulus dilated , abnormal
pronephric glomerulus cystic , abnormal
Show

 ZFA:0001634 perichondrium perichondrium edematous , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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