ENSDARG00000044281


Danio rerio

Features
Gene ID: ENSDARG00000044281
  
Biological name :erbin
  
Synonyms : erbb2 interacting protein / erbin
  
Possible biological names infered from orthology : Q80TH2 / Q96RT1
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 15454745
Gene end: 15599149
  
Corresponding Affymetrix probe sets: Dr.14832.1.A1_at (Zebrafish Array)   Dr.17250.1.A1_at (Zebrafish Array)   Dr.18442.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000104608
Ensembl peptide - ENSDARP00000153721
Ensembl peptide - ENSDARP00000137259
Ensembl peptide - ENSDARP00000133788
Ensembl peptide - ENSDARP00000106706
Ensembl peptide - ENSDARP00000082114
NCBI entrez gene - 566811     See in Manteia.
RefSeq - NM_001193543
RefSeq Peptide - NP_001180472
swissprot - B7ZVK8
swissprot - A0A0R4IEU0
swissprot - F1QPF0
swissprot - E7F9G8
swissprot - E7EYJ7
ZFIN ID - ZDB-GENE-061103-403
Ensembl - ENSDARG00000044281
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ERBINENSGALG00000014773Gallus gallus
 ERBINENSG00000112851Homo sapiens
 ErbinENSMUSG00000021709Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lrrc7 / leucine rich repeat containing 7 / Q96NW7*ENSDARG0000007967040
scrib / Q4H4B6 / scribbled planar cell polarity protein / Q14160* / Q80U72*ENSDARG0000000086123
lrrc1 / leucine rich repeat containing 1 / Q9BTT6*ENSDARG0000010268412
mfhas1 / malignant fibrous histiocytoma amplified sequence 1 / Q3V1N1* / Q9Y4C4* / Malignant fibrous histiocytoma-amplified sequence 1 homolog *ENSDARG0000007910412
shoc2 / Q1L8Y7 / SHOC2 leucine-rich repeat scaffold protein / O88520* / Q9UQ13* / Mus musculus soc-2 (suppressor of clear) homolog (C. elegans) (Shoc2), transcript variant 3, mRNA.*ENSDARG0000004085310
ascl1b / achaete-scute family bHLH transcription factor 1bENSDARG000000097029
lrrc40 / leucine rich repeat containing 40 / Q9H9A6* / leucine-rich repeat-containing protein 40 isoform b *ENSDARG000000177089
lrrc10 / leucine rich repeat containing 10 / Q5BKY1* / Q8K3W2* / Leucine-rich repeat-containing protein 10 *ENSDARG000000456125
lrrc30a / leucine rich repeat containing 30a / A6NM36* / LRRC30* / leucine rich repeat containing 30*ENSDARG000000297103


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR026906  Leucine rich repeat 5
 IPR032675  Leucine-rich repeat domain superfamily
 IPR032927  Erbin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IBA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016323 basolateral plasma membrane IBA
 molecular_functionGO:0005176 ErbB-2 class receptor binding IEA
 molecular_functionGO:0005178 integrin binding IBA


Pathways (from Reactome)
Pathway description
Signaling by ERBB2
Downregulation of ERBB2 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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