ENSDARG00000069433


Danio rerio

Features
Gene ID: ENSDARG00000069433
  
Biological name :tnk1
  
Synonyms : tnk1 / tyrosine kinase, non-receptor, 1
  
Possible biological names infered from orthology : Non-receptor tyrosine-protein kinase TNK1 / Q13470 / Q99ML2
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 26545502
Gene end: 26564784
  
Corresponding Affymetrix probe sets: Dr.7776.1.A1_at (Zebrafish Array)   NM_001080017_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000115699
Ensembl peptide - ENSDARP00000118604
Ensembl peptide - ENSDARP00000115555
NCBI entrez gene - 565029     See in Manteia.
RefSeq - NM_001080017
RefSeq - XM_005172298
RefSeq - XM_017356886
RefSeq Peptide - NP_001073486
swissprot - F1QB24
swissprot - E9QFR7
swissprot - E9QG30
ZFIN ID - ZDB-GENE-030131-7427
Ensembl - ENSDARG00000069433
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TNK1ENSG00000174292Homo sapiens
 Tnk1ENSMUSG00000001583Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tnk2b / tyrosine kinase, non-receptor, 2b / TNK2* / Q07912* / tyrosine kinase non receptor 2*ENSDARG0000010440944
tnk2a / tyrosine kinase, non-receptor, 2a / TNK2* / Q07912* / tyrosine kinase non receptor 2*ENSDARG0000009064643
ptk2ab / protein tyrosine kinase 2ab / PTK2* / P34152* / Q05397* / protein tyrosine kinase 2* / PTK2 protein tyrosine kinase 2*ENSDARG0000000467219
erbb4a / erb-b2 receptor tyrosine kinase 4aENSDARG0000006320719
si:ch73-383l1.1ENSDARG0000009040819
erbb3b / erb-b2 receptor tyrosine kinase 3b / ERBB3* / P21860* / Q61526* / erb-b2 receptor tyrosine kinase 3* / Receptor tyrosine-protein kinase erbB-3 *ENSDARG0000003699318
erbb2 / erb-b2 receptor tyrosine kinase 2 / P04626* / P70424* / Receptor tyrosine-protein kinase erbB-2 *ENSDARG0000002629418
ptk2bb / protein tyrosine kinase 2 beta, b / PTK2B* / Q14289* / Q9QVP9* / protein tyrosine kinase 2 beta* / PTK2 protein tyrosine kinase 2 beta*ENSDARG0000003957717
ptk2ba / protein tyrosine kinase 2 beta, a / PTK2B* / Q14289* / Q9QVP9* / protein tyrosine kinase 2 beta* / PTK2 protein tyrosine kinase 2 beta*ENSDARG0000002284117
erbb3a / erb-b2 receptor tyrosine kinase 3a / ERBB3* / P21860* / Q61526* / erb-b2 receptor tyrosine kinase 3* / Receptor tyrosine-protein kinase erbB-3 *ENSDARG0000000620217
zap70 / zeta chain of T cell receptor associated protein kinase 70 / P43403* / P43404* / zeta-chain (TCR) associated protein kinase*ENSDARG0000001575216
syk / spleen tyrosine kinase / P43405* / P48025* / spleen associated tyrosine kinase*ENSDARG0000000818616
ptk2aa / protein tyrosine kinase 2aa / PTK2* / P34152* / Q05397* / protein tyrosine kinase 2* / PTK2 protein tyrosine kinase 2*ENSDARG0000010045615
erbb4b / erb-b2 receptor tyrosine kinase 4bENSDARG0000008953611
LO018309.1 / ERBB4* / Q15303* / erb-b2 receptor tyrosine kinase 4*ENSDARG000000569093
egfra / epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) / ERBB4* / Q15303* / Q61527* / erb-b2 receptor tyrosine kinase 4* / Receptor tyr...ENSDARG000000138472


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001660  Sterile alpha motif domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR015116  Cdc42 binding domain-like
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0045087 innate immune response IBA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IBA
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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