ENSDARG00000078688


Danio rerio

Features
Gene ID: ENSDARG00000078688
  
Biological name :frs3
  
Synonyms : fibroblast growth factor receptor substrate 3 / frs3
  
Possible biological names infered from orthology : O43559 / Q91WJ0
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 40587551
Gene end: 40606273
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000146396
Ensembl peptide - ENSDARP00000129472
Ensembl peptide - ENSDARP00000156127
NCBI entrez gene - 100330147     See in Manteia.
RefSeq - XM_002662499
swissprot - E7F020
ZFIN ID - ZDB-GENE-131121-119
Ensembl - ENSDARG00000078688
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FRS3ENSGALG00000003447Gallus gallus
 FRS3ENSG00000137218Homo sapiens
 Frs3ENSMUSG00000023266Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
frs2a / fibroblast growth factor receptor substrate 2a / FRS2* / Q8C180* / Q8WU20* / fibroblast growth factor receptor substrate 2*ENSDARG0000004587337
frs2b / fibroblast growth factor receptor substrate 2b / FRS2* / Q8C180* / Q8WU20* / fibroblast growth factor receptor substrate 2*ENSDARG0000003735334


Protein motifs (from Interpro)
Interpro ID Name
 IPR002404  IRS-type PTB domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
FRS-mediated FGFR1 signaling
FRS-mediated FGFR2 signaling
FRS-mediated FGFR3 signaling
FRS-mediated FGFR4 signaling
RAF/MAP kinase cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000007356 fgf20a / fibroblast growth factor 20a / FGF20* / Q9NP95* / Q9ESL9* / fibroblast growth factor 20*  / complex / reaction
 ENSDARG00000004782 fgfr3 / fibroblast growth factor receptor 3 / P22607*  / complex / reaction
 ENSDARG00000011027 fgfr1a / Q90Z00 / fibroblast growth factor receptor 1a / FGFR1* / P11362* / P16092* / fibroblast growth factor receptor 1*  / reaction / complex
 ENSDARG00000030932 fgf10a / fibroblast growth factor 10a / FGF10* / O35565* / O15520* / fibroblast growth factor 10*  / reaction / complex
 ENSDARG00000011190 fgfr1b / fibroblast growth factor receptor 1b / FGFR1* / P16092* / P11362* / fibroblast growth factor receptor 1*  / reaction / complex
 ENSDARG00000043962 fgf18b / fibroblast growth factor 18b / FGF18* / O89101* / O76093* / fibroblast growth factor 18*  / complex / reaction
 ENSDARG00000020334 ptpn11a / protein tyrosine phosphatase, non-receptor type 11, a / PTPN11* / P35235* / Q06124* / Tyrosine-protein phosphatase non-receptor type 11 * / protein tyrosine phosphatase, non-recep...  / complex / reaction
 ENSDARG00000038059 grb2b / growth factor receptor-bound protein 2b / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / reaction / complex
 ENSDARG00000076294 klb / klotho beta / Q86Z14* / Q99N32* / Beta-klotho *  / complex / reaction
 ENSDARG00000076510 fgf22 / fibroblast growth factor 22 / Q9ESS2* / Q9HCT0*  / reaction / complex
 ENSDARG00000079862 kl / klotho / O35082* / Q9UEF7* / Klotho Klotho peptide*  / complex / reaction
 ENSDARG00000069105 fgfr4 / fibroblast growth factor receptor 4 / P22455*  / reaction / complex
 ENSDARG00000086070 fgf20b / fibroblast growth factor 20b / FGF20* / Q9NP95* / Q9ESL9* / fibroblast growth factor 20*  / complex / reaction
 ENSDARG00000098663 fgf19 / fibroblast growth factor 19 / Fgf15* / O95750* / O35622* / Fibroblast growth factor 15 *  / complex / reaction
 ENSDARG00000038225 nras / NRAS proto-oncogene, GTPase / P01111* / neuroblastoma ras oncogene*  / reaction
 ENSDARG00000005651 hrasb / -Ha-ras Harvey rat sarcoma viral oncogene homolog b / HRAS* / P01112* / Q61411* / HRas proto-oncogene, GTPase* / GTPase HRas GTPase HRas, N-terminally processed*  / reaction
 ENSDARG00000102778 fgf17 / Q6SJP8 / fibroblast growth factor 17 / O60258* / P63075*  / reaction / complex
 ENSDARG00000059387 fgf7 / fibroblast growth factor 7 / P21781*  / reaction / complex
 ENSDARG00000105276 grb2a / growth factor receptor-bound protein 2a / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / complex / reaction
 ENSDARG00000101540 fgf3 / P48802 / fibroblast growth factor 3 / P11487*  / complex / reaction
 ENSDARG00000100475 fgf10b / fibroblast growth factor 10b / FGF10* / O15520* / fibroblast growth factor 10*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr