ENSDARG00000097827


Danio rerio

Features
Gene ID: ENSDARG00000097827
  
Biological name :lrp1aa
  
Synonyms : low density lipoprotein receptor-related protein 1Aa / lrp1aa
  
Possible biological names infered from orthology : LDL receptor related protein 1 / LRP1 / Q07954
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 1628538
Gene end: 1864288
  
Corresponding Affymetrix probe sets: Dr.6174.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000133829
Ensembl peptide - ENSDARP00000142123
Ensembl peptide - ENSDARP00000142391
Ensembl peptide - ENSDARP00000142425
Ensembl peptide - ENSDARP00000142561
Ensembl peptide - ENSDARP00000142573
Ensembl peptide - ENSDARP00000129678
swissprot - A0A0H2UKL4
swissprot - A0A140LFU7
swissprot - A0A140LGL2
swissprot - A0A140LGP6
swissprot - A0A140LH31
swissprot - A0A140LH43
swissprot - X1WHG6
ZFIN ID - ZDB-GENE-030131-7889
Ensembl - ENSDARG00000097827
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LRP1ENSG00000123384Homo sapiens
 Lrp1ENSMUSG00000040249Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lrp1ab / low density lipoprotein receptor-related protein 1Ab / LRP1* / Q07954* / LDL receptor related protein 1*ENSDARG0000002914681
lrp1bb / low density lipoprotein receptor-related protein 1Bb / LRP1B* / Q9NZR2* / LDL receptor related protein 1B*ENSDARG0000006151756
lrp1ba / low density lipoprotein receptor-related protein 1Ba / LRP1B* / Q9NZR2* / LDL receptor related protein 1B*ENSDARG0000000478945
lrp2a / low density lipoprotein receptor-related protein 2a / LRP2* / P98164* / A2ARV4* / LDL receptor related protein 2* / low density lipoprotein receptor-related protein 2*ENSDARG0000010250635
lrp2b / low density lipoprotein receptor-related protein 2bENSDARG0000000790634
lrp1ba / low density lipoprotein receptor-related protein 1Ba / Gm19410*ENSDARG0000009417117
lrp5 / low density lipoprotein receptor-related protein 5 / O75197* / LDL receptor related protein 5*ENSDARG0000000692111
lrp13 / low-density lipoprotein receptor related-protein 13 / Gm19410*ENSDARG000000234798
si:dkey-88l16.3 / Gm19410*ENSDARG000000940558
lrp8 / low density lipoprotein receptor-related protein 8, apolipoprotein e receptor / Q14114* / Q924X6* / LDL receptor related protein 8* / Low-density lipoprotein receptor-related protein 8 *ENSDARG000000700747
vldlr / very low density lipoprotein receptor / P98155* / P98156*ENSDARG000000062577
ldlrb / low density lipoprotein receptor b / LDLR* / P35951* / P01130* / low density lipoprotein receptor*ENSDARG000000267596
ldlra / low density lipoprotein receptor a / LDLR* / P35951* / P01130* / low density lipoprotein receptor*ENSDARG000000294766
CABZ01071171.1 / Danio rerio low density lipoprotein receptor-related protein 4 (lrp4), mRNA. / LRP4* / Q8VI56* / O75096* / LDL receptor related protein 4* / Low-density lipoprotein recepto...ENSDARG000001163536
lrp6 / low density lipoprotein receptor-related protein 6 / O75581* / LDL receptor related protein 6*ENSDARG000001001435


Protein motifs (from Interpro)
Interpro ID Name
 IPR000033  LDLR class B repeat
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site
 IPR026823  Complement Clr-like EGF domain
 IPR030799  Low-density lipoprotein receptor-related protein 4
 IPR032485  Domain of unknown function DUF5050


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:1901342 regulation of vasculature development IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Scavenging of heme from plasma


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001117 post-vent region post-vent region wholly dorsalized , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel morphology , abnormal
Show

 ZFA:0001286 caudal vein plexus caudal vein plexus decreased branchiness , abnormal
Show

 ZFA:0005024 trunk vasculature trunk vasculature morphology , abnormal
Show

 ZFA:0005249 vasculature vasculature morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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