ENSDARG00000100143


Danio rerio

Features
Gene ID: ENSDARG00000100143
  
Biological name :lrp6
  
Synonyms : low density lipoprotein receptor-related protein 6 / lrp6
  
Possible biological names infered from orthology : LDL receptor related protein 6 / O75581
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 90048
Gene end: 100007
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000135077
swissprot - A0A0R4IL75
ZFIN ID - ZDB-GENE-090821-1
Ensembl - ENSDARG00000100143
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LRP6ENSGALG00000031503Gallus gallus
 LRP6ENSG00000070018Homo sapiens
 Lrp6ENSMUSG00000030201Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lrp5 / low density lipoprotein receptor-related protein 5 / O75197* / LDL receptor related protein 5*ENSDARG0000000692164
lrp2b / low density lipoprotein receptor-related protein 2bENSDARG0000000790631
lrp2a / low density lipoprotein receptor-related protein 2a / LRP2* / P98164* / A2ARV4* / LDL receptor related protein 2* / low density lipoprotein receptor-related protein 2*ENSDARG0000010250631
CABZ01071171.1 / Danio rerio low density lipoprotein receptor-related protein 4 (lrp4), mRNA. / LRP4* / Q8VI56* / O75096* / LDL receptor related protein 4* / Low-density lipoprotein recepto...ENSDARG0000011635327
lrp1aa / low density lipoprotein receptor-related protein 1Aa / LRP1* / Q07954* / LDL receptor related protein 1*ENSDARG0000009782726
lrp1ab / low density lipoprotein receptor-related protein 1Ab / LRP1* / Q07954* / LDL receptor related protein 1*ENSDARG0000002914626
lrp1bb / low density lipoprotein receptor-related protein 1Bb / LRP1B* / Q9NZR2* / LDL receptor related protein 1B*ENSDARG0000006151724
lrp1ba / low density lipoprotein receptor-related protein 1Ba / LRP1B* / Q9NZR2* / LDL receptor related protein 1B*ENSDARG0000000478918
lrp1ba / low density lipoprotein receptor-related protein 1Ba / Gm19410*ENSDARG0000009417117
si:dkey-88l16.3 / Gm19410*ENSDARG000000940555
lrp13 / low-density lipoprotein receptor related-protein 13 / Gm19410*ENSDARG000000234794
lrp8 / low density lipoprotein receptor-related protein 8, apolipoprotein e receptor / Q14114* / Q924X6* / LDL receptor related protein 8* / Low-density lipoprotein receptor-related protein 8 *ENSDARG000000700742
vldlr / very low density lipoprotein receptor / P98155* / P98156*ENSDARG000000062572
ldlrb / low density lipoprotein receptor b / LDLR* / P35951* / P01130* / low density lipoprotein receptor*ENSDARG000000267592
ldlra / low density lipoprotein receptor a / LDLR* / P35951* / P01130* / low density lipoprotein receptor*ENSDARG000000294762


Protein motifs (from Interpro)
Interpro ID Name
 IPR000033  LDLR class B repeat
 IPR000742  EGF-like domain
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Negative regulation of TCF-dependent signaling by WNT ligand antagonists
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Regulation of FZD by ubiquitination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism wholly dorsalized , abnormal
whole organism wholly ventralized , abnormal
whole organism curved , abnormal
whole organism decreased length , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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