ENSG00000029725


Homo sapiens

Features
Gene ID: ENSG00000029725
  
Biological name :RABEP1
  
Synonyms : Q15276 / rabaptin, RAB GTPase binding effector protein 1 / RABEP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p13.2
Gene start: 5282265
Gene end: 5385812
  
Corresponding Affymetrix probe sets: 203223_at (Human Genome U133 Plus 2.0 Array)   214552_s_at (Human Genome U133 Plus 2.0 Array)   225064_at (Human Genome U133 Plus 2.0 Array)   225092_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466981
Ensembl peptide - ENSP00000460980
Ensembl peptide - ENSP00000482983
Ensembl peptide - ENSP00000339569
Ensembl peptide - ENSP00000445408
Ensembl peptide - ENSP00000459550
NCBI entrez gene - 9135     See in Manteia.
OMIM - 603616
RefSeq - XM_017025295
RefSeq - NM_001083585
RefSeq - NM_001291581
RefSeq - NM_004703
RefSeq - XM_011524060
RefSeq - XM_017025294
RefSeq Peptide - NP_001077054
RefSeq Peptide - NP_004694
RefSeq Peptide - NP_001278510
swissprot - K7ENJ9
swissprot - A0A087WZZ3
swissprot - Q15276
swissprot - I3L2B8
swissprot - I3L456
Ensembl - ENSG00000029725
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rabep1ENSDARG00000059600Danio rerio
 RABEP1ENSGALG00000001737Gallus gallus
 O35551ENSMUSG00000020817Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9H5N1 / RABEP2 / rabaptin, RAB GTPase binding effector protein 2ENSG0000017754825


Protein motifs (from Interpro)
Interpro ID Name
 IPR003914  Rabaptin
 IPR015390  Rabaptin, GTPase-Rab5 binding domain
 IPR018514  Rabaptin coiled-coil domain
 IPR029880  Rabaptin-5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IMP
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0061025 membrane fusion TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome TAS
 cellular_componentGO:0030139 endocytic vesicle IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031901 early endosome membrane TAS
 cellular_componentGO:0032991 protein-containing complex IMP
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI


Pathways (from Reactome)
Pathway description
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000103365 GGA2 / Q9UJY4 / golgi associated, gamma adaptin ear containing, ARF binding protein 2  / complex
 ENSG00000111540 RAB5B / P61020 / RAB5B, member RAS oncogene family  / complex
 ENSG00000144566 RAB5A / P20339 / RAB5A, member RAS oncogene family  / complex
 ENSG00000154710 Q9UJ41 / RABGEF1 / RAB guanine nucleotide exchange factor 1  / complex
 ENSG00000108774 RAB5C / P51148 / RAB5C, member RAS oncogene family  / complex
 ENSG00000274611 Q8IZP1 / TBC1D3 / TBC1 domain family member 3  / complex / reaction
 ENSG00000100083 GGA1 / Q9UJY5 / golgi associated, gamma adaptin ear containing, ARF binding protein 1  / complex
 ENSG00000125447 GGA3 / Q9NZ52 / golgi associated, gamma adaptin ear containing, ARF binding protein 3  / complex






 

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