ENSG00000090565


Homo sapiens

Features
Gene ID: ENSG00000090565
  
Biological name :RAB11FIP3
  
Synonyms : O75154 / RAB11 family interacting protein 3 / RAB11FIP3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 425619
Gene end: 523011
  
Corresponding Affymetrix probe sets: 203933_at (Human Genome U133 Plus 2.0 Array)   214999_s_at (Human Genome U133 Plus 2.0 Array)   228613_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000412502
Ensembl peptide - ENSP00000404331
Ensembl peptide - ENSP00000415919
Ensembl peptide - ENSP00000262305
Ensembl peptide - ENSP00000399614
Ensembl peptide - ENSP00000399644
NCBI entrez gene - 9727     See in Manteia.
OMIM - 608738
RefSeq - XM_011522765
RefSeq - NM_001142272
RefSeq - NM_014700
RefSeq - XM_005255713
RefSeq - XM_005255714
RefSeq - XM_005255715
RefSeq - XM_011522764
RefSeq Peptide - NP_001135744
RefSeq Peptide - NP_055515
swissprot - H0Y7F9
swissprot - O75154
swissprot - A0A0A0MSV1
swissprot - X6RFI8
swissprot - F6X994
Ensembl - ENSG00000090565
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8CHD8ENSMUSG00000037098Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q86YS3 / RAB11FIP4 / RAB11 family interacting protein 4ENSG0000013124232


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR019018  Rab-binding domain FIP-RBD
 IPR032920  Rab11 family-interacting protein 3
 IPR037245  FIP-RBD, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000910 cytokinesis IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016192 vesicle-mediated transport TAS
 biological_processGO:0032456 endocytic recycling IDA
 biological_processGO:0032465 regulation of cytokinesis IMP
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070164 negative regulation of adiponectin secretion IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0032154 cleavage furrow IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0045171 intercellular bridge IDA
 cellular_componentGO:0055037 recycling endosome IDA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017137 Rab GTPase binding NAS
 molecular_functionGO:0030306 ADP-ribosylation factor binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051959 dynein light intermediate chain binding IPI


Pathways (from Reactome)
Pathway description
VxPx cargo-targeting to cilium


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000070729 CNGB1 / Q14028 / cyclic nucleotide gated channel beta 1  / reaction / complex
 ENSG00000103769 P62491 / RAB11A / RAB11A, member RAS oncogene family  / complex / reaction
 ENSG00000163914 RHO / P08100 / rhodopsin  / complex / reaction
 ENSG00000132259 CNGA4 / Q8IV77 / cyclic nucleotide gated channel alpha 4  / complex / reaction
 ENSG00000090565 O75154 / RAB11FIP3 / RAB11 family interacting protein 3  / complex
 ENSG00000127328 Q96QF0 / RAB3IP / RAB3A interacting protein  / complex / reaction
 ENSG00000183862 CNGA2 / Q16280 / cyclic nucleotide gated channel alpha 2  / complex / reaction
 ENSG00000167461 RAB8A / P61006 / RAB8A, member RAS oncogene family  / reaction / complex
 ENSG00000008710 PKD1 / P98161 / polycystin 1, transient receptor potential channel interacting  / complex / reaction
 ENSG00000168374 ARF4 / P18085 / ADP ribosylation factor 4  / reaction / complex
 ENSG00000153317 ASAP1 / Q9ULH1 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 1  / complex / reaction






 

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contact: otassy@igbmc.fr