ENSG00000127328


Homo sapiens

Features
Gene ID: ENSG00000127328
  
Biological name :RAB3IP
  
Synonyms : Q96QF0 / RAB3A interacting protein / RAB3IP
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q15
Gene start: 69738681
Gene end: 69823204
  
Corresponding Affymetrix probe sets: 1565799_at (Human Genome U133 Plus 2.0 Array)   1565800_x_at (Human Genome U133 Plus 2.0 Array)   223471_at (Human Genome U133 Plus 2.0 Array)   228432_at (Human Genome U133 Plus 2.0 Array)   231399_at (Human Genome U133 Plus 2.0 Array)   238526_at (Human Genome U133 Plus 2.0 Array)   238853_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450355
Ensembl peptide - ENSP00000448773
Ensembl peptide - ENSP00000448944
Ensembl peptide - ENSP00000247833
Ensembl peptide - ENSP00000355381
Ensembl peptide - ENSP00000368086
Ensembl peptide - ENSP00000368092
Ensembl peptide - ENSP00000419216
Ensembl peptide - ENSP00000432634
Ensembl peptide - ENSP00000436304
Ensembl peptide - ENSP00000447300
Ensembl peptide - ENSP00000447499
Ensembl peptide - ENSP00000448027
Ensembl peptide - ENSP00000448102
Ensembl peptide - ENSP00000448218
Ensembl peptide - ENSP00000448688
NCBI entrez gene - 117177     See in Manteia.
OMIM - 608686
RefSeq - XM_017018777
RefSeq - NM_001024647
RefSeq - NM_001278402
RefSeq - NM_022456
RefSeq - NM_175623
RefSeq - NM_175624
RefSeq - NM_175625
RefSeq - XM_006719226
RefSeq - XM_006719227
RefSeq - XM_017018773
RefSeq - XM_017018774
RefSeq - XM_017018776
RefSeq Peptide - NP_001265331
RefSeq Peptide - NP_071901
RefSeq Peptide - NP_783322
RefSeq Peptide - NP_783323
RefSeq Peptide - NP_783324
RefSeq Peptide - NP_001019818
swissprot - J3KPG1
swissprot - F8VNX9
swissprot - Q96QF0
swissprot - F8VTR6
swissprot - H0YD03
swissprot - H0YHP4
swissprot - H0YI02
swissprot - H0YI66
Ensembl - ENSG00000127328
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab3ipENSDARG00000101908Danio rerio
 ENSGALG00000009959Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8TBN0 / RAB3IL1 / RAB3A interacting protein like 1ENSG0000016799443
AC025263.2ENSG0000025805215


Protein motifs (from Interpro)
Interpro ID Name
 IPR009449  GDP/GTP exchange factor Sec2, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006612 protein targeting to membrane IDA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0097711 ciliary basal body-plasma membrane docking TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity TAS


Pathways (from Reactome)
Pathway description
Anchoring of the basal body to the plasma membrane
VxPx cargo-targeting to cilium
BBSome-mediated cargo-targeting to cilium
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000070729 CNGB1 / Q14028 / cyclic nucleotide gated channel beta 1  / complex / reaction
 ENSG00000203668 CHML / P26374 / CHM like, Rab escort protein 2  / reaction
 ENSG00000167461 RAB8A / P61006 / RAB8A, member RAS oncogene family  / reaction / complex
 ENSG00000103494 Q68CZ1 / RPGRIP1L / RPGRIP1 like  / complex / reaction
 ENSG00000131697 NPHP4 / O75161 / nephrocystin 4  / complex / reaction
 ENSG00000144061 NPHP1 / O15259 / nephrocystin 1  / complex / reaction
 ENSG00000188419 CHM / P24386 / CHM, Rab escort protein 1  / reaction
 ENSG00000057608 GDI2 / P50395 / GDP dissociation inhibitor 2  / reaction
 ENSG00000203879 GDI1 / P31150 / GDP dissociation inhibitor 1  / reaction
 ENSG00000103769 P62491 / RAB11A / RAB11A, member RAS oncogene family  / reaction / complex
 ENSG00000090565 O75154 / RAB11FIP3 / RAB11 family interacting protein 3  / reaction / complex
 ENSG00000008710 PKD1 / P98161 / polycystin 1, transient receptor potential channel interacting  / reaction / complex
 ENSG00000163914 RHO / P08100 / rhodopsin  / reaction / complex
 ENSG00000183862 CNGA2 / Q16280 / cyclic nucleotide gated channel alpha 2  / reaction / complex
 ENSG00000153317 ASAP1 / Q9ULH1 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 1  / complex / reaction
 ENSG00000132259 CNGA4 / Q8IV77 / cyclic nucleotide gated channel alpha 4  / reaction / complex






 

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