ENSG00000100433


Homo sapiens

Features
Gene ID: ENSG00000100433
  
Biological name :KCNK10
  
Synonyms : KCNK10 / P57789 / potassium two pore domain channel subfamily K member 10
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q31.3
Gene start: 88180103
Gene end: 88326907
  
Corresponding Affymetrix probe sets: 1556927_at (Human Genome U133 Plus 2.0 Array)   220727_at (Human Genome U133 Plus 2.0 Array)   231230_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000310568
Ensembl peptide - ENSP00000312811
Ensembl peptide - ENSP00000343104
Ensembl peptide - ENSP00000452587
NCBI entrez gene - 54207     See in Manteia.
OMIM - 605873
RefSeq - XM_011536840
RefSeq - NM_021161
RefSeq - NM_138317
RefSeq - NM_138318
RefSeq Peptide - NP_066984
RefSeq Peptide - NP_612190
RefSeq Peptide - NP_612191
swissprot - P57789
swissprot - G3V5Y5
Ensembl - ENSG00000100433
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnk10aENSDARG00000062849Danio rerio
 kcnk10bENSDARG00000045956Danio rerio
 KCNK10ENSGALG00000010598Gallus gallus
 Kcnk10ENSMUSG00000033854Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNK2 / O95069 / potassium two pore domain channel subfamily K member 2ENSG0000008248247
KCNK4 / Q9NYG8 / potassium two pore domain channel subfamily K member 4ENSG0000018245031
KCNK5 / O95279 / potassium two pore domain channel subfamily K member 5ENSG0000016462620
KCNK17 / Q96T54 / potassium two pore domain channel subfamily K member 17ENSG0000012478018
KCNK1 / O00180 / potassium two pore domain channel subfamily K member 1ENSG0000013575017
KCNK3 / O14649 / potassium two pore domain channel subfamily K member 3ENSG0000017130317
KCNK16 / Q96T55 / potassium two pore domain channel subfamily K member 16ENSG0000009598117
KCNK9 / Q9NPC2 / potassium two pore domain channel subfamily K member 9ENSG0000016942716
KCNK15 / Q9H427 / potassium two pore domain channel subfamily K member 15ENSG0000012424916
KCNK6 / Q9Y257 / potassium two pore domain channel subfamily K member 6ENSG0000009933715
KCNK7 / Q9Y2U2 / potassium two pore domain channel subfamily K member 7ENSG0000017333815


Protein motifs (from Interpro)
Interpro ID Name
 IPR003280  Two pore domain potassium channel
 IPR003976  Two pore domain potassium channel, TREK
 IPR013099  Potassium channel domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007613 memory IEA
 biological_processGO:0030322 stabilization of membrane potential IBA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0022841 potassium ion leak channel activity IBA


Pathways (from Reactome)
Pathway description
TWIK related potassium channel (TREK)
Phase 4 - resting membrane potential


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100433 KCNK10 / P57789 / potassium two pore domain channel subfamily K member 10  / complex
 ENSG00000182450 KCNK4 / Q9NYG8 / potassium two pore domain channel subfamily K member 4  / complex
 ENSG00000082482 KCNK2 / O95069 / potassium two pore domain channel subfamily K member 2  / complex






 

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