ENSG00000124780


Homo sapiens

Features
Gene ID: ENSG00000124780
  
Biological name :KCNK17
  
Synonyms : KCNK17 / potassium two pore domain channel subfamily K member 17 / Q96T54
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.2
Gene start: 39299001
Gene end: 39314553
  
Corresponding Affymetrix probe sets: 224049_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362328
Ensembl peptide - ENSP00000401271
NCBI entrez gene - 89822     See in Manteia.
OMIM - 607370
RefSeq - NM_001135111
RefSeq - NM_031460
RefSeq Peptide - NP_001128583
RefSeq Peptide - NP_113648
swissprot - Q96T54
Ensembl - ENSG00000124780
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnk17ENSDARG00000105453Danio rerio
 KCNK17ENSGALG00000010068Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNK4 / Q9NYG8 / potassium two pore domain channel subfamily K member 4ENSG0000018245033
KCNK16 / Q96T55 / potassium two pore domain channel subfamily K member 16ENSG0000009598132
KCNK5 / O95279 / potassium two pore domain channel subfamily K member 5ENSG0000016462630
KCNK2 / O95069 / potassium two pore domain channel subfamily K member 2ENSG0000008248230
KCNK10 / P57789 / potassium two pore domain channel subfamily K member 10ENSG0000010043329
KCNK6 / Q9Y257 / potassium two pore domain channel subfamily K member 6ENSG0000009933726
KCNK15 / Q9H427 / potassium two pore domain channel subfamily K member 15ENSG0000012424923
KCNK3 / O14649 / potassium two pore domain channel subfamily K member 3ENSG0000017130322
KCNK9 / Q9NPC2 / potassium two pore domain channel subfamily K member 9ENSG0000016942721
KCNK1 / O00180 / potassium two pore domain channel subfamily K member 1ENSG0000013575021
KCNK7 / Q9Y2U2 / potassium two pore domain channel subfamily K member 7ENSG0000017333819


Protein motifs (from Interpro)
Interpro ID Name
 IPR003092  Two pore domain potassium channel, TASK family
 IPR003280  Two pore domain potassium channel
 IPR013099  Potassium channel domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0030322 stabilization of membrane potential IBA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005267 potassium channel activity TAS
 molecular_functionGO:0022841 potassium ion leak channel activity IBA


Pathways (from Reactome)
Pathway description
TWIK-related alkaline pH activated K+ channel (TALK)
Phase 4 - resting membrane potential


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000124780 KCNK17 / Q96T54 / potassium two pore domain channel subfamily K member 17  / complex






 

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