ENSG00000164626


Homo sapiens

Features
Gene ID: ENSG00000164626
  
Biological name :KCNK5
  
Synonyms : KCNK5 / O95279 / potassium two pore domain channel subfamily K member 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.2
Gene start: 39188973
Gene end: 39229450
  
Corresponding Affymetrix probe sets: 219615_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000352527
NCBI entrez gene - 8645     See in Manteia.
OMIM - 603493
RefSeq - XM_005249456
RefSeq - NM_003740
RefSeq Peptide - NP_003731
swissprot - O95279
swissprot - A0A024RD32
Ensembl - ENSG00000164626
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnk5aENSDARG00000023587Danio rerio
 KCNK5ENSGALG00000034077Gallus gallus
 Kcnk5ENSMUSG00000023243Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNK10 / P57789 / potassium two pore domain channel subfamily K member 10ENSG0000010043322
KCNK4 / Q9NYG8 / potassium two pore domain channel subfamily K member 4ENSG0000018245021
KCNK17 / Q96T54 / potassium two pore domain channel subfamily K member 17ENSG0000012478020
KCNK2 / O95069 / potassium two pore domain channel subfamily K member 2ENSG0000008248219
KCNK16 / Q96T55 / potassium two pore domain channel subfamily K member 16ENSG0000009598118
KCNK3 / O14649 / potassium two pore domain channel subfamily K member 3ENSG0000017130317
KCNK6 / Q9Y257 / potassium two pore domain channel subfamily K member 6ENSG0000009933717
KCNK9 / Q9NPC2 / potassium two pore domain channel subfamily K member 9ENSG0000016942716
KCNK15 / Q9H427 / potassium two pore domain channel subfamily K member 15ENSG0000012424915
KCNK1 / O00180 / potassium two pore domain channel subfamily K member 1ENSG0000013575015
KCNK7 / Q9Y2U2 / potassium two pore domain channel subfamily K member 7ENSG0000017333814


Protein motifs (from Interpro)
Interpro ID Name
 IPR003092  Two pore domain potassium channel, TASK family
 IPR003280  Two pore domain potassium channel
 IPR013099  Potassium channel domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport TAS
 biological_processGO:0007588 excretion TAS
 biological_processGO:0030322 stabilization of membrane potential IBA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0071804 cellular potassium ion transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity TAS
 molecular_functionGO:0022841 potassium ion leak channel activity IBA


Pathways (from Reactome)
Pathway description
Phase 4 - resting membrane potential


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000164626 KCNK5 / O95279 / potassium two pore domain channel subfamily K member 5  / complex






 

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