ENSG00000124249


Homo sapiens

Features
Gene ID: ENSG00000124249
  
Biological name :KCNK15
  
Synonyms : KCNK15 / potassium two pore domain channel subfamily K member 15 / Q9H427
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q13.12
Gene start: 44745780
Gene end: 44752313
  
Corresponding Affymetrix probe sets: 220540_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361952
NCBI entrez gene - 60598     See in Manteia.
OMIM - 607368
RefSeq - NM_022358
RefSeq Peptide - NP_071753
swissprot - Q9H427
Ensembl - ENSG00000124249
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnk15ENSDARG00000077371Danio rerio
 KCNK15ENSGALG00000042705Gallus gallus
 Kcnk15ENSMUSG00000035238Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNK9 / Q9NPC2 / potassium two pore domain channel subfamily K member 9ENSG0000016942755
KCNK3 / O14649 / potassium two pore domain channel subfamily K member 3ENSG0000017130353
KCNK2 / O95069 / potassium two pore domain channel subfamily K member 2ENSG0000008248226
KCNK10 / P57789 / potassium two pore domain channel subfamily K member 10ENSG0000010043326
KCNK16 / Q96T55 / potassium two pore domain channel subfamily K member 16ENSG0000009598125
KCNK4 / Q9NYG8 / potassium two pore domain channel subfamily K member 4ENSG0000018245025
KCNK1 / O00180 / potassium two pore domain channel subfamily K member 1ENSG0000013575023
KCNK17 / Q96T54 / potassium two pore domain channel subfamily K member 17ENSG0000012478023
KCNK5 / O95279 / potassium two pore domain channel subfamily K member 5ENSG0000016462623
KCNK6 / Q9Y257 / potassium two pore domain channel subfamily K member 6ENSG0000009933722
KCNK7 / Q9Y2U2 / potassium two pore domain channel subfamily K member 7ENSG0000017333821


Protein motifs (from Interpro)
Interpro ID Name
 IPR003092  Two pore domain potassium channel, TASK family
 IPR003280  Two pore domain potassium channel
 IPR008073  Potassium channel subfamily K member 15
 IPR013099  Potassium channel domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0030322 stabilization of membrane potential IBA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0061337 cardiac conduction TAS
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005267 potassium channel activity TAS
 molecular_functionGO:0022841 potassium ion leak channel activity IBA


Pathways (from Reactome)
Pathway description
Phase 4 - resting membrane potential


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000124249 KCNK15 / Q9H427 / potassium two pore domain channel subfamily K member 15  / complex






 

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