ENSG00000100767


Homo sapiens

Features
Gene ID: ENSG00000100767
  
Biological name :PAPLN
  
Synonyms : O95428 / papilin, proteoglycan like sulfated glycoprotein / PAPLN
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q24.2
Gene start: 73237497
Gene end: 73274640
  
Corresponding Affymetrix probe sets: 226435_at (Human Genome U133 Plus 2.0 Array)   233896_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453664
Ensembl peptide - ENSP00000452455
Ensembl peptide - ENSP00000495882
Ensembl peptide - ENSP00000216658
Ensembl peptide - ENSP00000345395
Ensembl peptide - ENSP00000451053
Ensembl peptide - ENSP00000451729
Ensembl peptide - ENSP00000451803
NCBI entrez gene - 89932     See in Manteia.
OMIM - 617785
RefSeq - XM_017021750
RefSeq - XM_011537292
RefSeq - XM_011537293
RefSeq - XM_011537294
RefSeq - XM_011537295
RefSeq - XM_011537296
RefSeq - XM_017021749
RefSeq - NM_173462
RefSeq - XM_011537290
RefSeq - XM_011537291
RefSeq Peptide - NP_775733
swissprot - G3V5P6
swissprot - H0YJA1
swissprot - H0YMM2
swissprot - B5MDP7
swissprot - O95428
Ensembl - ENSG00000100767
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 paplnaENSDARG00000027867Danio rerio
 paplnbENSDARG00000042186Danio rerio
 PAPLNENSGALG00000009315Gallus gallus
 PaplnENSMUSG00000021223Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9P2N4 / ADAMTS9 / ADAM metallopeptidase with thrombospondin type 1 motif 9ENSG0000016363820
Q6UY14 / ADAMTSL4 / ADAMTS like 4ENSG0000014338219
P59510 / ADAMTS20 / ADAM metallopeptidase with thrombospondin type 1 motif 20ENSG0000017315718
THSD4 / Q6ZMP0 / thrombospondin type 1 domain containing 4ENSG0000018772018
P82987 / ADAMTSL3 / ADAMTS like 3ENSG0000015621818
Q8N6G6 / ADAMTSL1 / ADAMTS like 1ENSG0000017803118
Q76LX8 / ADAMTS13 / ADAM metallopeptidase with thrombospondin type 1 motif 13ENSG0000016032317
Q86TH1 / ADAMTSL2 / ADAMTS like 2ENSG0000019785916
Q8TE58 / ADAMTS15 / ADAM metallopeptidase with thrombospondin type 1 motif 15ENSG0000016610611
Q9UHI8 / ADAMTS1 / ADAM metallopeptidase with thrombospondin type 1 motif 1ENSG0000015473411
Q9UNA0 / ADAMTS5 / ADAM metallopeptidase with thrombospondin type 1 motif 5ENSG000001547369
Q9UP79 / ADAMTS8 / ADAM metallopeptidase with thrombospondin type 1 motif 8ENSG000001349179
O75173 / ADAMTS4 / ADAM metallopeptidase with thrombospondin type 1 motif 4ENSG000001588598


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR010294  ADAM-TS Spacer 1
 IPR010909  PLAC
 IPR013098  Immunoglobulin I-set
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site
 IPR036179  Immunoglobulin-like domain superfamily
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily
 IPR036880  Pancreatic trypsin inhibitor Kunitz domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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