ENSG00000187720


Homo sapiens

Features
Gene ID: ENSG00000187720
  
Biological name :THSD4
  
Synonyms : Q6ZMP0 / thrombospondin type 1 domain containing 4 / THSD4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q23
Gene start: 71096952
Gene end: 71783383
  
Corresponding Affymetrix probe sets: 1555816_at (Human Genome U133 Plus 2.0 Array)   1555817_s_at (Human Genome U133 Plus 2.0 Array)   219153_s_at (Human Genome U133 Plus 2.0 Array)   222835_at (Human Genome U133 Plus 2.0 Array)   226506_at (Human Genome U133 Plus 2.0 Array)   232944_at (Human Genome U133 Plus 2.0 Array)   234323_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000484438
Ensembl peptide - ENSP00000261862
Ensembl peptide - ENSP00000347484
Ensembl peptide - ENSP00000350413
NCBI entrez gene - 79875     See in Manteia.
OMIM - 614476
RefSeq - XM_017022586
RefSeq - NM_001286429
RefSeq - NM_024817
RefSeq - XM_017022582
RefSeq - XM_017022583
RefSeq - XM_017022584
RefSeq - XM_017022585
RefSeq - XM_006720692
RefSeq - XM_011522043
RefSeq - XM_011522044
RefSeq Peptide - NP_001273358
RefSeq Peptide - NP_079093
swissprot - Q6ZMP0
swissprot - A0A087X1T0
Ensembl - ENSG00000187720
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adamtsl7ENSDARG00000055439Danio rerio
 THSD4ENSGALG00000004087Gallus gallus
 Thsd4ENSMUSG00000032289Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6UY14 / ADAMTSL4 / ADAMTS like 4ENSG0000014338238
Q86TH1 / ADAMTSL2 / ADAMTS like 2ENSG0000019785924
Q9P2N4 / ADAMTS9 / ADAM metallopeptidase with thrombospondin type 1 motif 9ENSG0000016363824
P59510 / ADAMTS20 / ADAM metallopeptidase with thrombospondin type 1 motif 20ENSG0000017315723
PAPLN / O95428 / papilin, proteoglycan like sulfated glycoproteinENSG0000010076723
P82987 / ADAMTSL3 / ADAMTS like 3ENSG0000015621821
Q8N6G6 / ADAMTSL1 / ADAMTS like 1ENSG0000017803121
Q76LX8 / ADAMTS13 / ADAM metallopeptidase with thrombospondin type 1 motif 13ENSG0000016032318
Q9UHI8 / ADAMTS1 / ADAM metallopeptidase with thrombospondin type 1 motif 1ENSG0000015473414
Q8TE58 / ADAMTS15 / ADAM metallopeptidase with thrombospondin type 1 motif 15ENSG0000016610614
Q9UP79 / ADAMTS8 / ADAM metallopeptidase with thrombospondin type 1 motif 8ENSG0000013491713
Q9UNA0 / ADAMTS5 / ADAM metallopeptidase with thrombospondin type 1 motif 5ENSG0000015473612
O75173 / ADAMTS4 / ADAM metallopeptidase with thrombospondin type 1 motif 4ENSG0000015885911


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR010294  ADAM-TS Spacer 1
 IPR010909  PLAC
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0048251 elastic fiber assembly IEA
 cellular_componentGO:0001527 microfibril IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0031012 extracellular matrix HDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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