ENSG00000178031


Homo sapiens

Features
Gene ID: ENSG00000178031
  
Biological name :ADAMTSL1
  
Synonyms : ADAMTSL1 / ADAMTS like 1 / Q8N6G6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: p22.2
Gene start: 17906563
Gene end: 18910950
  
Corresponding Affymetrix probe sets: 1552457_a_at (Human Genome U133 Plus 2.0 Array)   1552808_at (Human Genome U133 Plus 2.0 Array)   224371_at (Human Genome U133 Plus 2.0 Array)   229585_at (Human Genome U133 Plus 2.0 Array)   237217_at (Human Genome U133 Plus 2.0 Array)   239909_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000373362
Ensembl peptide - ENSP00000369944
Ensembl peptide - ENSP00000401157
Ensembl peptide - ENSP00000490168
Ensembl peptide - ENSP00000440472
Ensembl peptide - ENSP00000276935
Ensembl peptide - ENSP00000327887
Ensembl peptide - ENSP00000369911
Ensembl peptide - ENSP00000369918
Ensembl peptide - ENSP00000369921
Ensembl peptide - ENSP00000369940
NCBI entrez gene - 92949     See in Manteia.
OMIM - 609198
RefSeq - XM_017015314
RefSeq - XM_011518064
RefSeq - XM_011518067
RefSeq - XM_011518068
RefSeq - XM_011518070
RefSeq - XM_017015310
RefSeq - XM_017015311
RefSeq - XM_017015312
RefSeq - XM_017015313
RefSeq - NM_001040272
RefSeq - NM_052866
RefSeq - XM_011518063
RefSeq Peptide - NP_001035362
RefSeq Peptide - NP_443098
swissprot - F8WEP3
swissprot - H7BYE3
swissprot - A6NIB9
swissprot - A0A1B0GUM2
swissprot - Q8N6G6
swissprot - A2A343
Ensembl - ENSG00000178031
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000034760Gallus gallus
 ENSGALG00000020554Gallus gallus
 Q8BLI0ENSMUSG00000066113Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P82987 / ADAMTSL3 / ADAMTS like 3ENSG0000015621842
P59510 / ADAMTS20 / ADAM metallopeptidase with thrombospondin type 1 motif 20ENSG0000017315718
Q9P2N4 / ADAMTS9 / ADAM metallopeptidase with thrombospondin type 1 motif 9ENSG0000016363817
PAPLN / O95428 / papilin, proteoglycan like sulfated glycoproteinENSG0000010076713
Q76LX8 / ADAMTS13 / ADAM metallopeptidase with thrombospondin type 1 motif 13ENSG0000016032313
THSD4 / Q6ZMP0 / thrombospondin type 1 domain containing 4ENSG0000018772012
Q6UY14 / ADAMTSL4 / ADAMTS like 4ENSG0000014338212
Q86TH1 / ADAMTSL2 / ADAMTS like 2ENSG0000019785911
Q9UHI8 / ADAMTS1 / ADAM metallopeptidase with thrombospondin type 1 motif 1ENSG000001547348
Q8TE58 / ADAMTS15 / ADAM metallopeptidase with thrombospondin type 1 motif 15ENSG000001661068
Q9UP79 / ADAMTS8 / ADAM metallopeptidase with thrombospondin type 1 motif 8ENSG000001349177
O75173 / ADAMTS4 / ADAM metallopeptidase with thrombospondin type 1 motif 4ENSG000001588596
Q9UNA0 / ADAMTS5 / ADAM metallopeptidase with thrombospondin type 1 motif 5ENSG000001547366


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR010294  ADAM-TS Spacer 1
 IPR010909  PLAC
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0036066 protein O-linked fucosylation TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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