ENSG00000111181


Homo sapiens

Features
Gene ID: ENSG00000111181
  
Biological name :SLC6A12
  
Synonyms : P48065 / SLC6A12 / solute carrier family 6 member 12
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p13.33
Gene start: 190077
Gene end: 214570
  
Corresponding Affymetrix probe sets: 206058_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000446082
Ensembl peptide - ENSP00000439351
Ensembl peptide - ENSP00000444268
Ensembl peptide - ENSP00000352702
Ensembl peptide - ENSP00000380464
Ensembl peptide - ENSP00000399136
NCBI entrez gene - 6539     See in Manteia.
OMIM - 603080
RefSeq - XM_017019841
RefSeq - NM_001122848
RefSeq - NM_001206931
RefSeq - NM_003044
RefSeq - XM_005253747
RefSeq - XM_005253748
RefSeq - XM_006719005
RefSeq - XM_011521010
RefSeq - NM_001122847
RefSeq Peptide - NP_003035
RefSeq Peptide - NP_001116319
RefSeq Peptide - NP_001116320
RefSeq Peptide - NP_001193860
swissprot - P48065
swissprot - F5H4L6
swissprot - F5H2T6
Ensembl - ENSG00000111181
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC6A12ENSGALG00000019290Gallus gallus
 Slc6a12ENSMUSG00000030109Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NSD5 / SLC6A13 / solute carrier family 6 member 13ENSG0000001037969
P48066 / SLC6A11 / solute carrier family 6 member 11ENSG0000013216465
P31641 / SLC6A6 / solute carrier family 6 member 6ENSG0000013138959
P48029 / SLC6A8 / solute carrier family 6 member 8ENSG0000013082152
P30531 / SLC6A1 / solute carrier family 6 member 1ENSG0000015710347
Q9Y345 / SLC6A5 / solute carrier family 6 member 5ENSG0000016597044
Q99884 / SLC6A7 / solute carrier family 6 member 7ENSG0000001108343
Q01959 / SLC6A3 / solute carrier family 6 member 3ENSG0000014231941
P23975 / SLC6A2 / solute carrier family 6 member 2ENSG0000010354641
P48067 / SLC6A9 / solute carrier family 6 member 9ENSG0000019651741
Q9UN76 / SLC6A14 / solute carrier family 6 member 14ENSG0000026810440
P31645 / SLC6A4 / solute carrier family 6 member 4ENSG0000010857640


Protein motifs (from Interpro)
Interpro ID Name
 IPR000175  Sodium:neurotransmitter symporter
 IPR002983  Sodium:neurotransmitter symporter, betaine
 IPR037272  Sodium:neurotransmitter symporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003333 amino acid transmembrane transport IEA
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0006865 amino acid transport TAS
 biological_processGO:0015812 gamma-aminobutyric acid transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 molecular_functionGO:0005215 transporter activity IBA
 molecular_functionGO:0005328 neurotransmitter:sodium symporter activity IEA
 molecular_functionGO:0005332 gamma-aminobutyric acid:sodium symporter activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015171 amino acid transmembrane transporter activity TAS
 molecular_functionGO:0015293 symporter activity IEA


Pathways (from Reactome)
Pathway description
Amino acid transport across the plasma membrane
Na+/Cl- dependent neurotransmitter transporters
Creatine metabolism
Reuptake of GABA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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