ENSG00000131389


Homo sapiens

Features
Gene ID: ENSG00000131389
  
Biological name :SLC6A6
  
Synonyms : P31641 / SLC6A6 / solute carrier family 6 member 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p25.1
Gene start: 14402576
Gene end: 14489349
  
Corresponding Affymetrix probe sets: 205920_at (Human Genome U133 Plus 2.0 Array)   205921_s_at (Human Genome U133 Plus 2.0 Array)   211030_s_at (Human Genome U133 Plus 2.0 Array)   228754_at (Human Genome U133 Plus 2.0 Array)   228756_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000402059
Ensembl peptide - ENSP00000480890
Ensembl peptide - ENSP00000482560
Ensembl peptide - ENSP00000482391
Ensembl peptide - ENSP00000482220
Ensembl peptide - ENSP00000481946
Ensembl peptide - ENSP00000481625
Ensembl peptide - ENSP00000399522
NCBI entrez gene - 6533     See in Manteia.
OMIM - 186854
RefSeq - XM_011534031
RefSeq - NM_001134367
RefSeq - NM_001134368
RefSeq - NM_003043
RefSeq - XM_006713307
RefSeq - XM_011534030
RefSeq Peptide - NP_001127839
RefSeq Peptide - NP_001127840
RefSeq Peptide - NP_003034
swissprot - A0A087WZ59
swissprot - A0A087WYY8
swissprot - A0A087WYN0
swissprot - A0A087WY96
swissprot - H7C1B9
swissprot - P31641
swissprot - C9JPV1
Ensembl - ENSG00000131389
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc6a6aENSDARG00000012534Danio rerio
 slc6a6bENSDARG00000098438Danio rerio
 SLC6A6ENSGALG00000006425Gallus gallus
 O35316ENSMUSG00000030096Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NSD5 / SLC6A13 / solute carrier family 6 member 13ENSG0000001037951
P48065 / SLC6A12 / solute carrier family 6 member 12ENSG0000011118151
P48066 / SLC6A11 / solute carrier family 6 member 11ENSG0000013216451
P48029 / SLC6A8 / solute carrier family 6 member 8ENSG0000013082146
P30531 / SLC6A1 / solute carrier family 6 member 1ENSG0000015710341
Q9Y345 / SLC6A5 / solute carrier family 6 member 5ENSG0000016597035
P23975 / SLC6A2 / solute carrier family 6 member 2ENSG0000010354635
Q99884 / SLC6A7 / solute carrier family 6 member 7ENSG0000001108335
Q9UN76 / SLC6A14 / solute carrier family 6 member 14ENSG0000026810434
Q01959 / SLC6A3 / solute carrier family 6 member 3ENSG0000014231934
P31645 / SLC6A4 / solute carrier family 6 member 4ENSG0000010857634
P48067 / SLC6A9 / solute carrier family 6 member 9ENSG0000019651733


Protein motifs (from Interpro)
Interpro ID Name
 IPR000175  Sodium:neurotransmitter symporter
 IPR002434  Sodium:neurotransmitter symporter, taurine
 IPR037272  Sodium:neurotransmitter symporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003333 amino acid transmembrane transport IBA
 biological_processGO:0006520 cellular amino acid metabolic process TAS
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0006865 amino acid transport TAS
 biological_processGO:0015734 taurine transport IBA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 molecular_functionGO:0005328 neurotransmitter:sodium symporter activity IEA
 molecular_functionGO:0005368 taurine transmembrane transporter activity IEA
 molecular_functionGO:0005369 taurine:sodium symporter activity TAS
 molecular_functionGO:0015171 amino acid transmembrane transporter activity TAS
 molecular_functionGO:0015293 symporter activity IEA


Pathways (from Reactome)
Pathway description
Amino acid transport across the plasma membrane
Na+/Cl- dependent neurotransmitter transporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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