ENSG00000132164


Homo sapiens

Features
Gene ID: ENSG00000132164
  
Biological name :SLC6A11
  
Synonyms : P48066 / SLC6A11 / solute carrier family 6 member 11
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p25.3
Gene start: 10816200
Gene end: 10940733
  
Corresponding Affymetrix probe sets: 1554724_at (Human Genome U133 Plus 2.0 Array)   207048_at (Human Genome U133 Plus 2.0 Array)   230286_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000254488
Ensembl peptide - ENSP00000404120
NCBI entrez gene - 6538     See in Manteia.
OMIM - 607952
RefSeq - XM_017007073
RefSeq - NM_001317406
RefSeq - NM_014229
RefSeq Peptide - NP_055044
RefSeq Peptide - NP_001304335
swissprot - P48066
Ensembl - ENSG00000132164
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc6a11bENSDARG00000087981Danio rerio
 SLC6A11ENSGALG00000004879Gallus gallus
 P31650ENSMUSG00000030307Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NSD5 / SLC6A13 / solute carrier family 6 member 13ENSG0000001037965
P48065 / SLC6A12 / solute carrier family 6 member 12ENSG0000011118163
P31641 / SLC6A6 / solute carrier family 6 member 6ENSG0000013138958
P48029 / SLC6A8 / solute carrier family 6 member 8ENSG0000013082152
P30531 / SLC6A1 / solute carrier family 6 member 1ENSG0000015710348
Q99884 / SLC6A7 / solute carrier family 6 member 7ENSG0000001108341
Q9Y345 / SLC6A5 / solute carrier family 6 member 5ENSG0000016597041
P48067 / SLC6A9 / solute carrier family 6 member 9ENSG0000019651739
P31645 / SLC6A4 / solute carrier family 6 member 4ENSG0000010857639
Q9UN76 / SLC6A14 / solute carrier family 6 member 14ENSG0000026810438
P23975 / SLC6A2 / solute carrier family 6 member 2ENSG0000010354638
Q01959 / SLC6A3 / solute carrier family 6 member 3ENSG0000014231937


Protein motifs (from Interpro)
Interpro ID Name
 IPR000175  Sodium:neurotransmitter symporter
 IPR002982  Sodium:neurotransmitter symporter, GABA, GAT-3
 IPR037272  Sodium:neurotransmitter symporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0015812 gamma-aminobutyric acid transport IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005215 transporter activity IBA
 molecular_functionGO:0005328 neurotransmitter:sodium symporter activity IEA
 molecular_functionGO:0005332 gamma-aminobutyric acid:sodium symporter activity TAS
 molecular_functionGO:0015293 symporter activity IEA
 molecular_functionGO:0042165 neurotransmitter binding IEA


Pathways (from Reactome)
Pathway description
Na+/Cl- dependent neurotransmitter transporters
Creatine metabolism
Reuptake of GABA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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