ENSG00000116032


Homo sapiens

Features
Gene ID: ENSG00000116032
  
Biological name :GRIN3B
  
Synonyms : glutamate ionotropic receptor NMDA type subunit 3B / GRIN3B / O60391
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 1000419
Gene end: 1009732
  
Corresponding Affymetrix probe sets: 233892_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000234389
NCBI entrez gene - 116444     See in Manteia.
OMIM - 606651
RefSeq - NM_138690
RefSeq - XM_017026243
RefSeq Peptide - NP_619635
swissprot - O60391
Ensembl - ENSG00000116032
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grin3baENSDARG00000005364Danio rerio
 grin3bbENSDARG00000098667Danio rerio
 GRIN3BENSGALG00000026241Gallus gallus
 Grin3bENSMUSG00000035745Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRIN3A / Q8TCU5 / glutamate ionotropic receptor NMDA type subunit 3AENSG0000019878549
GRIN2C / Q14957 / glutamate ionotropic receptor NMDA type subunit 2CENSG0000016150925
GRIN2D / O15399 / glutamate ionotropic receptor NMDA type subunit 2DENSG0000010546425
GRIN2A / Q12879 / glutamate ionotropic receptor NMDA type subunit 2AENSG0000018345423
GRIN2B / Q13224 / glutamate ionotropic receptor NMDA type subunit 2BENSG0000027307922
GRIN1 / Q05586 / glutamate ionotropic receptor NMDA type subunit 1ENSG0000017688420
GRIK3 / Q13003 / glutamate ionotropic receptor kainate type subunit 3ENSG0000016387317
GRIA4 / P48058 / glutamate ionotropic receptor AMPA type subunit 4ENSG0000015257817
GRIA1 / P42261 / glutamate ionotropic receptor AMPA type subunit 1ENSG0000015551116
GRIK1 / P39086 / glutamate ionotropic receptor kainate type subunit 1ENSG0000017118916
GRIA3 / P42263 / glutamate ionotropic receptor AMPA type subunit 3ENSG0000012567516
GRID2 / O43424 / glutamate ionotropic receptor delta type subunit 2ENSG0000015220816
GRIK5 / Q16478 / glutamate ionotropic receptor kainate type subunit 5ENSG0000010573716
GRIA2 / P42262 / glutamate ionotropic receptor AMPA type subunit 2ENSG0000012025116
GRIK2 / Q13002 / glutamate ionotropic receptor kainate type subunit 2ENSG0000016441816
GRIK4 / Q16099 / glutamate ionotropic receptor kainate type subunit 4ENSG0000014940315
GRID1 / Q9ULK0 / glutamate ionotropic receptor delta type subunit 1ENSG0000018277115


Protein motifs (from Interpro)
Interpro ID Name
 IPR001320  Ionotropic glutamate receptor
 IPR001508  Ionotropic glutamate receptor, metazoa
 IPR019594  Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035235 ionotropic glutamate receptor signaling pathway ISS
 biological_processGO:0051205 protein insertion into membrane ISS
 biological_processGO:0051924 regulation of calcium ion transport IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0017146 NMDA selective glutamate receptor complex IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004970 ionotropic glutamate receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005234 extracellularly glutamate-gated ion channel activity IEA
 molecular_functionGO:0005261 cation channel activity ISS
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0016594 glycine binding ISS
 molecular_functionGO:0030594 neurotransmitter receptor activity ISS
 molecular_functionGO:0042165 neurotransmitter binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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