ENSG00000122779


Homo sapiens

Features
Gene ID: ENSG00000122779
  
Biological name :TRIM24
  
Synonyms : O15164 / TRIM24 / tripartite motif containing 24
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q33
Gene start: 138460334
Gene end: 138589993
  
Corresponding Affymetrix probe sets: 1569316_at (Human Genome U133 Plus 2.0 Array)   204391_x_at (Human Genome U133 Plus 2.0 Array)   213301_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000390829
Ensembl peptide - ENSP00000340507
NCBI entrez gene - 8805     See in Manteia.
OMIM - 603406
RefSeq - NM_003852
RefSeq - NM_015905
RefSeq Peptide - NP_003843
RefSeq Peptide - NP_056989
swissprot - O15164
swissprot - A0A024R784
Ensembl - ENSG00000122779
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TRIM24ENSGALG00000012823Gallus gallus
 Q64127ENSMUSG00000029833Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UPN9 / TRIM33 / tripartite motif containing 33ENSG0000019732351
O15016 / TRIM66 / tripartite motif containing 66ENSG0000016643630
Q13263 / TRIM28 / tripartite motif containing 28ENSG0000013072624
Q2Q1W2 / TRIM71 / tripartite motif containing 71ENSG0000020655712
TRIM2 / Q9C040 / tripartite motif containing 2ENSG0000010965412
TRIM3 / O75382 / tripartite motif containing 3ENSG0000011017111
Q9H8W5 / TRIM45 / tripartite motif containing 45ENSG0000013425311
Q9BRZ2 / TRIM56 / tripartite motif containing 56ENSG0000016987110


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001487  Bromodomain
 IPR001841  Zinc finger, RING-type
 IPR001965  Zinc finger, PHD-type
 IPR003649  B-box, C-terminal
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR018359  Bromodomain, conserved site
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR036427  Bromodomain-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0030163 protein catabolic process IMP
 biological_processGO:0031647 regulation of protein stability IMP
 biological_processGO:0042981 regulation of apoptotic process IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0055074 calcium ion homeostasis IEA
 biological_processGO:0070562 regulation of vitamin D receptor signaling pathway IEA
 biological_processGO:0071391 cellular response to estrogen stimulus IDA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005719 nuclear euchromatin IEA
 cellular_componentGO:0005726 perichromatin fibrils IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0002039 p53 binding IPI
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016922 nuclear receptor binding IEA
 molecular_functionGO:0034056 estrogen response element binding IDA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA
 molecular_functionGO:0070577 lysine-acetylated histone binding IDA


Pathways (from Reactome)
Pathway description
Signaling by cytosolic FGFR1 fusion mutants
Signaling by FGFR1 in disease
Signaling by BRAF and RAF fusions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000122779 O15164 / TRIM24 / tripartite motif containing 24  / complex






 

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