ENSG00000140682


Homo sapiens

Features
Gene ID: ENSG00000140682
  
Biological name :TGFB1I1
  
Synonyms : O43294 / TGFB1I1 / transforming growth factor beta 1 induced transcript 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p11.2
Gene start: 31471585
Gene end: 31477960
  
Corresponding Affymetrix probe sets: 209651_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454688
Ensembl peptide - ENSP00000456482
Ensembl peptide - ENSP00000456783
Ensembl peptide - ENSP00000457586
Ensembl peptide - ENSP00000459283
Ensembl peptide - ENSP00000355117
Ensembl peptide - ENSP00000378327
Ensembl peptide - ENSP00000378332
Ensembl peptide - ENSP00000455709
Ensembl peptide - ENSP00000456341
NCBI entrez gene - 7041     See in Manteia.
OMIM - 602353
RefSeq - NM_015927
RefSeq - NM_001042454
RefSeq - NM_001164719
RefSeq Peptide - NP_057011
RefSeq Peptide - NP_001158191
RefSeq Peptide - NP_001035919
swissprot - O43294
swissprot - A0A024QZE7
swissprot - H3BN49
swissprot - H3BQC4
swissprot - H3BRP2
swissprot - H3BS04
swissprot - H3BSN4
swissprot - I3L209
Ensembl - ENSG00000140682
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q62219ENSMUSG00000030782Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PXN / P49023 / paxillinENSG0000008915952
LPXN / O60711 / leupaxinENSG0000011003140
PDLIM7 / Q9NR12 / PDZ and LIM domain 7ENSG0000019692324
LDB3 / O75112 / LIM domain binding 3ENSG0000012236723
PDLIM5 / Q96HC4 / PDZ and LIM domain 5ENSG0000016311022
LIMS1 / P48059 / LIM zinc finger domain containing 1ENSG0000016975615
FHL3 / Q13643 / four and a half LIM domains 3ENSG0000018338615
FHL2 / Q14192 / four and a half LIM domains 2ENSG0000011564115
LIMS2 / Q7Z4I7 / LIM zinc finger domain containing 2ENSG0000007216315
FHL5 / Q5TD97 / four and a half LIM domains 5ENSG0000011221412
FHL1 / Q13642 / four and a half LIM domains 1ENSG0000002226712
AC013271.1ENSG000002843375
AC112229.3ENSG000002572075
LIMS3 / P0CW19 / LIM zinc finger domain containing 3ENSG000002569771
LIMS4 / P0CW20 / LIM zinc finger domain containing 4ENSG000002566711


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type
 IPR017305  Leupaxin/Paxillin/TGFB1I1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0009408 response to heat IEA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IDA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016331 morphogenesis of embryonic epithelium IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway IDA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IDA
 biological_processGO:0030521 androgen receptor signaling pathway NAS
 biological_processGO:0030579 ubiquitin-dependent SMAD protein catabolic process IDA
 biological_processGO:0030855 epithelial cell differentiation IEA
 biological_processGO:0045165 cell fate commitment IEA
 biological_processGO:0045599 negative regulation of fat cell differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated NAS
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031012 extracellular matrix IDA
 molecular_functionGO:0003713 transcription coactivator activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048495 Roundabout binding IPI
 molecular_functionGO:0050681 androgen receptor binding NAS
 molecular_functionGO:0070411 I-SMAD binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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