ENSG00000153922


Homo sapiens

Features
Gene ID: ENSG00000153922
  
Biological name :CHD1
  
Synonyms : CHD1 / chromodomain helicase DNA binding protein 1 / O14646
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q21.1
Gene start: 98853985
Gene end: 98928957
  
Corresponding Affymetrix probe sets: 204258_at (Human Genome U133 Plus 2.0 Array)   235791_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000284049
Ensembl peptide - ENSP00000422589
Ensembl peptide - ENSP00000479403
Ensembl peptide - ENSP00000483667
Ensembl peptide - ENSP00000422225
NCBI entrez gene - 1105     See in Manteia.
OMIM - 602118
RefSeq - XM_011543112
RefSeq - NM_001270
RefSeq - XM_005271866
RefSeq - XM_005271867
RefSeq Peptide - NP_001261
swissprot - O14646
swissprot - H0Y8V4
swissprot - H0Y8Z0
swissprot - A0A087WVF4
Ensembl - ENSG00000153922
  
Related genetic diseases (OMIM): 617682 - Pilarowski-Bjornsson syndrome, 617682
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chd1ENSDARG00000103787Danio rerio
 ENSGALG00000031327Gallus gallus
 CHD1ZENSGALG00000014642Gallus gallus
 Chd1ENSMUSG00000023852Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHD2 / O14647 / chromodomain helicase DNA binding protein 2ENSG0000017357562
CHD3 / Q12873 / chromodomain helicase DNA binding protein 3ENSG0000017000428
CHD5 / Q8TDI0 / chromodomain helicase DNA binding protein 5ENSG0000011625428
CHD4 / Q14839 / chromodomain helicase DNA binding protein 4ENSG0000011164227
CHD7 / Q9P2D1 / chromodomain helicase DNA binding protein 7ENSG0000017131625
CHD9 / Q3L8U1 / chromodomain helicase DNA binding protein 9ENSG0000017720025
CHD6 / Q8TD26 / chromodomain helicase DNA binding protein 6ENSG0000012417725
CHD8 / Q9HCK8 / chromodomain helicase DNA binding protein 8ENSG0000010088824
AC013394.1ENSG000002797653


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR000953  Chromo/chromo shadow domain
 IPR001650  Helicase, C-terminal
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR016197  Chromo-like domain superfamily
 IPR023779  Chromo domain, conserved site
 IPR023780  Chromo domain
 IPR025260  Domain of unknown function DUF4208
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0016569 covalent chromatin modification IMP
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0043923 positive regulation by host of viral transcription IMP
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity TAS
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0035064 methylated histone binding IMP


Pathways (from Reactome)
Pathway description
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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