ENSG00000168818


Homo sapiens

Features
Gene ID: ENSG00000168818
  
Biological name :STX18
  
Synonyms : Q9P2W9 / STX18 / syntaxin 18
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p16.2
Gene start: 4415742
Gene end: 4542346
  
Corresponding Affymetrix probe sets: 218763_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000422376
Ensembl peptide - ENSP00000426648
Ensembl peptide - ENSP00000305810
NCBI entrez gene - 53407     See in Manteia.
OMIM - 606046
RefSeq - XM_017008297
RefSeq - NM_016930
RefSeq - XM_011513480
RefSeq - XM_011513483
RefSeq - XM_011513485
RefSeq Peptide - NP_058626
swissprot - D6RF48
swissprot - D6RC71
swissprot - Q9P2W9
Ensembl - ENSG00000168818
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stx18ENSDARG00000035763Danio rerio
 STX18ENSGALG00000015012Gallus gallus
 Stx18ENSMUSG00000029125Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006012  Syntaxin/epimorphin, conserved site
 IPR019529  SNARE-complex protein Syntaxin-18, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0061025 membrane fusion IEA
 biological_processGO:0090158 endoplasmic reticulum membrane organization IMP
 biological_processGO:1902117 positive regulation of organelle assembly IMP
 biological_processGO:1902953 positive regulation of ER to Golgi vesicle-mediated transport IMP
 biological_processGO:1903358 regulation of Golgi organization IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031201 SNARE complex IBA
 molecular_functionGO:0005484 SNAP receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding IEA


Pathways (from Reactome)
Pathway description
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000086827 ZW10 / O43264 / zw10 kinetochore protein  / reaction
 ENSG00000113734 BNIP1 / Q12981 / BCL2 interacting protein 1  / complex
 ENSG00000053501 USE1 / Q9NZ43 / unconventional SNARE in the ER 1  / complex
 ENSG00000135249 RINT1 / Q6NUQ1 / RAD50 interactor 1  / reaction
 ENSG00000105402 NAPA / P54920 / NSF attachment protein alpha  / reaction / complex
 ENSG00000151779 NBAS / A2RRP1 / neuroblastoma amplified sequence  / reaction
 ENSG00000073969 NSF / P46459 / N-ethylmaleimide sensitive factor, vesicle fusing ATPase  / complex / reaction
 ENSG00000265808 O75396 / SEC22B / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)  / complex






 

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