ENSG00000177463


Homo sapiens

Features
Gene ID: ENSG00000177463
  
Biological name :NR2C2
  
Synonyms : NR2C2 / nuclear receptor subfamily 2 group C member 2 / P49116
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p25.1
Gene start: 14947584
Gene end: 15053600
  
Corresponding Affymetrix probe sets: 206038_s_at (Human Genome U133 Plus 2.0 Array)   225477_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000402272
Ensembl peptide - ENSP00000401807
Ensembl peptide - ENSP00000412473
Ensembl peptide - ENSP00000483059
Ensembl peptide - ENSP00000413438
Ensembl peptide - ENSP00000320447
Ensembl peptide - ENSP00000376814
Ensembl peptide - ENSP00000384463
Ensembl peptide - ENSP00000388387
Ensembl peptide - ENSP00000391473
NCBI entrez gene - 7182     See in Manteia.
OMIM - 601426
RefSeq - XM_017007120
RefSeq - XM_011534058
RefSeq - XM_011534059
RefSeq - XM_011534061
RefSeq - XM_011534063
RefSeq - XM_011534064
RefSeq - XM_011534065
RefSeq - XM_011534066
RefSeq - XM_017007118
RefSeq - XM_017007119
RefSeq - NM_001291694
RefSeq - NM_003298
RefSeq Peptide - NP_001278623
RefSeq Peptide - NP_003289
swissprot - F2YGU2
swissprot - H7C3L1
swissprot - C9JMI6
swissprot - P49116
swissprot - C9J2Y1
swissprot - H7C3R1
swissprot - C9JKS0
Ensembl - ENSG00000177463
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nr2c2ENSDARG00000042477Danio rerio
 NR2C2ENSGALG00000008519Gallus gallus
 Nr2c2ENSMUSG00000005893Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NR2C1 / P13056 / nuclear receptor subfamily 2 group C member 1ENSG0000012079860
NR2F1 / P10589 / nuclear receptor subfamily 2 group F member 1ENSG0000017574525
NR2F2 / P24468 / nuclear receptor subfamily 2 group F member 2ENSG0000018555124
RXRG / P48443 / retinoid X receptor gammaENSG0000014317123
RXRA / P19793 / retinoid X receptor alphaENSG0000018635023
NR2F6 / P10588 / nuclear receptor subfamily 2 group F member 6ENSG0000016011322
RXRB / P28702 / retinoid X receptor betaENSG0000020423122
NR2E1 / Q9Y466 / nuclear receptor subfamily 2 group E member 1ENSG0000011233322
HNF4G / Q14541 / hepatocyte nuclear factor 4 gammaENSG0000016474920
NR2E3 / Q9Y5X4 / nuclear receptor subfamily 2 group E member 3ENSG0000027857020
HNF4A / P41235 / hepatocyte nuclear factor 4 alphaENSG0000010107619


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type
 IPR035500  Nuclear hormone receptor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated TAS
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr