ENSG00000160113


Homo sapiens

Features
Gene ID: ENSG00000160113
  
Biological name :NR2F6
  
Synonyms : NR2F6 / nuclear receptor subfamily 2 group F member 6 / P10588
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.11
Gene start: 17231883
Gene end: 17245940
  
Corresponding Affymetrix probe sets: 209261_s_at (Human Genome U133 Plus 2.0 Array)   209262_s_at (Human Genome U133 Plus 2.0 Array)   213354_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000471686
Ensembl peptide - ENSP00000291442
NCBI entrez gene - 2063     See in Manteia.
OMIM - 132880
RefSeq - NM_005234
RefSeq Peptide - NP_005225
swissprot - P10588
swissprot - F1D8R3
swissprot - M0R175
Ensembl - ENSG00000160113
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nr2f6aENSDARG00000003607Danio rerio
 nr2f6bENSDARG00000003165Danio rerio
 NR2F6ENSGALG00000043010Gallus gallus
 Nr2f6ENSMUSG00000002393Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NR2F2 / P24468 / nuclear receptor subfamily 2 group F member 2ENSG0000018555163
NR2F1 / P10589 / nuclear receptor subfamily 2 group F member 1ENSG0000017574563
RXRA / P19793 / retinoid X receptor alphaENSG0000018635037
NR2E3 / Q9Y5X4 / nuclear receptor subfamily 2 group E member 3ENSG0000027857037
RXRG / P48443 / retinoid X receptor gammaENSG0000014317136
RXRB / P28702 / retinoid X receptor betaENSG0000020423136
NR2E1 / Q9Y466 / nuclear receptor subfamily 2 group E member 1ENSG0000011233334
HNF4A / P41235 / hepatocyte nuclear factor 4 alphaENSG0000010107634
NR2C2 / P49116 / nuclear receptor subfamily 2 group C member 2ENSG0000017746334
NR2C1 / P13056 / nuclear receptor subfamily 2 group C member 1ENSG0000012079833
HNF4G / Q14541 / hepatocyte nuclear factor 4 gammaENSG0000016474932


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003068  Transcription factor COUP
 IPR013088  Zinc finger, NHR/GATA-type
 IPR035500  Nuclear hormone receptor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0043153 entrainment of circadian clock by photoperiod IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0048666 neuron development IEA
 biological_processGO:0050965 detection of temperature stimulus involved in sensory perception of pain IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0004887 thyroid hormone receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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