ENSG00000164749


Homo sapiens

Features
Gene ID: ENSG00000164749
  
Biological name :HNF4G
  
Synonyms : hepatocyte nuclear factor 4 gamma / HNF4G / Q14541
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q21.13
Gene start: 75407914
Gene end: 75566843
  
Corresponding Affymetrix probe sets: 207456_at (Human Genome U133 Plus 2.0 Array)   232271_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000346339
Ensembl peptide - ENSP00000379701
NCBI entrez gene - 3174     See in Manteia.
OMIM - 605966
RefSeq - XM_017013376
RefSeq - NM_004133
RefSeq - XM_011517516
RefSeq - XM_017013373
RefSeq - XM_017013374
RefSeq - XM_017013375
RefSeq Peptide - NP_001317490
RefSeq Peptide - NP_004124
swissprot - Q14541
swissprot - F1D8Q4
Ensembl - ENSG00000164749
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hnf4gENSDARG00000071565Danio rerio
 HNF4GENSGALG00000042621Gallus gallus
 Hnf4gENSMUSG00000017688Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HNF4A / P41235 / hepatocyte nuclear factor 4 alphaENSG0000010107673
RXRA / P19793 / retinoid X receptor alphaENSG0000018635034
RXRG / P48443 / retinoid X receptor gammaENSG0000014317133
RXRB / P28702 / retinoid X receptor betaENSG0000020423133
NR2F6 / P10588 / nuclear receptor subfamily 2 group F member 6ENSG0000016011329
NR2F2 / P24468 / nuclear receptor subfamily 2 group F member 2ENSG0000018555128
NR2F1 / P10589 / nuclear receptor subfamily 2 group F member 1ENSG0000017574528
NR2E3 / Q9Y5X4 / nuclear receptor subfamily 2 group E member 3ENSG0000027857027
NR2C2 / P49116 / nuclear receptor subfamily 2 group C member 2ENSG0000017746327
NR2E1 / Q9Y466 / nuclear receptor subfamily 2 group E member 1ENSG0000011233327
NR2C1 / P13056 / nuclear receptor subfamily 2 group C member 1ENSG0000012079826


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003068  Transcription factor COUP
 IPR013088  Zinc finger, NHR/GATA-type
 IPR035500  Nuclear hormone receptor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IC
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of gene expression in beta cells
Nuclear Receptor transcription pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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