ENSMUSG00000017688


Mus musculus

Features
Gene ID: ENSMUSG00000017688
  
Biological name :Hnf4g
  
Synonyms : hepatocyte nuclear factor 4 gamma / Hnf4g
  
Possible biological names infered from orthology : Q14541
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: A1
Gene start: 3508030
Gene end: 3658052
  
Corresponding Affymetrix probe sets: 10490755 (MoGene1.0st)   1422182_at (Mouse Genome 430 2.0 Array)   1450518_at (Mouse Genome 430 2.0 Array)   1460127_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000104031
Ensembl peptide - ENSMUSP00000104030
NCBI entrez gene - 30942     See in Manteia.
MGI - MGI:1353604
RefSeq - NM_013920
RefSeq - XM_006530072
RefSeq Peptide - NP_038948
swissprot - E9QPS1
swissprot - Q059V1
Ensembl - ENSMUSG00000017688
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hnf4gENSDARG00000071565Danio rerio
 HNF4GENSGALG00000042621Gallus gallus
 HNF4GENSG00000164749Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hnf4a / P49698 / Hepatocyte nuclear factor 4-alpha / P41235*ENSMUSG0000001795074
Rxrb / P28704 / retinoid X receptor beta / P28702*ENSMUSG0000003965636
Rxra / P28700 / retinoid X receptor alpha / P19793*ENSMUSG0000001584636
Rxrg / P28705 / Retinoic acid receptor RXR-gamma / P48443* / retinoid X receptor gamma*ENSMUSG0000001584334
Nr2f6 / P43136 / Nuclear receptor subfamily 2 group F member 6 / P10588*ENSMUSG0000000239330
Nr2f1 / nuclear receptor subfamily 2, group F, member 1 / P10589*ENSMUSG0000006917129
Nr2f2 / P43135 / nuclear receptor subfamily 2, group F, member 2 / P24468*ENSMUSG0000003055129
Nr2c2 / P49117 / nuclear receptor subfamily 2, group C, member 2 / P49116*ENSMUSG0000000589328
Nr2e1 / Q64104 / nuclear receptor subfamily 2, group E, member 1 / Q9Y466*ENSMUSG0000001980328
Nr2c1 / Q505F1 / Nuclear receptor subfamily 2 group C member 1 / P13056*ENSMUSG0000000589727
Nr2e3 / Q9QXZ7 / Photoreceptor-specific nuclear receptor / Q9Y5X4* / nuclear receptor subfamily 2 group E member 3*ENSMUSG0000003229227


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003068  Transcription factor COUP
 IPR013088  Zinc finger, NHR/GATA-type
 IPR035500  Nuclear hormone receptor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Gt(ROSA)26Sortm1(CAG-EGFP)Luo/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001447 abnormal nest building behavior "deviation from the usual behavior of mice to build sleeping nests out of any available materials; also of female mice to bulid nests to protect offspring" [J:42758, What s wrong with my mouse?:ISBN 0-471-31639-3]
Show

Allelic Composition: Gt(ROSA)26Sortm1(CAG-EGFP)Luo/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001943 abnormal respiration "anomaly in the movement of gases into and out of the lung " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gt(ROSA)26Sortm1(CAG-EGFP)Luo/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003064 decreased coping response "reduced ability to respond productively to a stressful situation" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Gt(ROSA)26Sortm1(CAG-EGFP)Luo/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003313 abnormal locomotor activation "altered ability or desire of an animal to initiate locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sortm1(CAG-EGFP)Luo/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0005450 abnormal energy expenditure "utilization of calories that differs from the norm " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gt(ROSA)26Sortm1(CAG-EGFP)Luo/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0011940 decreased food intake "reduction in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith]
Show

Allelic Composition: Gt(ROSA)26Sortm1(CAG-EGFP)Luo/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0011942 decreased fluid intake "reduction in the total amount of fluid taken in over time when compared to the normal state" [MGI:csmith]
Show

Allelic Composition: Gt(ROSA)26Sortm1(CAG-EGFP)Luo/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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