ENSG00000179772


Homo sapiens

Features
Gene ID: ENSG00000179772
  
Biological name :FOXS1
  
Synonyms : forkhead box S1 / FOXS1 / O43638
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q11.21
Gene start: 31844301
Gene end: 31845619
  
Corresponding Affymetrix probe sets: 229731_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000365145
NCBI entrez gene - 2307     See in Manteia.
OMIM - 602939
RefSeq - NM_004118
RefSeq Peptide - NP_004109
swissprot - O43638
Ensembl - ENSG00000179772
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FOXS1ENSGALG00000043015Gallus gallus
 Foxs1ENSMUSG00000074676Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXC1 / Q12948 / forkhead box C1ENSG0000005459838
FOXC2 / Q99958 / forkhead box C2ENSG0000017669238
FOXL2 / P58012 / forkhead box L2ENSG0000018377030
FOXL1 / Q12952 / forkhead box L1ENSG0000017667830
FOXB1 / Q99853 / forkhead box B1ENSG0000017195626
FOXB2 / Q5VYV0 / forkhead box B2ENSG0000020461226
FOXA2 / Q9Y261 / forkhead box A2ENSG0000012579826
FOXI1 / Q12951 / forkhead box I1ENSG0000016826926
FOXA1 / P55317 / forkhead box A1ENSG0000012951425
FOXI3 / A8MTJ6 / forkhead box I3ENSG0000021433625
FOXI2 / Q6ZQN5 / forkhead box I2ENSG0000018676625
FOXA3 / P55318 / forkhead box A3ENSG0000017060822


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR033067  Forkhead box protein S1
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001568 blood vessel development ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0040018 positive regulation of multicellular organism growth IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0050885 neuromuscular process controlling balance IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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