ENSG00000171956


Homo sapiens

Features
Gene ID: ENSG00000171956
  
Biological name :FOXB1
  
Synonyms : forkhead box B1 / FOXB1 / Q99853
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q22.2
Gene start: 60004222
Gene end: 60061730
  
Corresponding Affymetrix probe sets: 208513_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000379369
NCBI entrez gene - 27023     See in Manteia.
RefSeq - NM_012182
RefSeq Peptide - NP_036314
swissprot - Q99853
Ensembl - ENSG00000171956
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxb1aENSDARG00000089042Danio rerio
 foxb1bENSDARG00000053650Danio rerio
 FOXB1ENSGALG00000027498Gallus gallus
 Foxb1ENSMUSG00000059246Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXB2 / Q5VYV0 / forkhead box B2ENSG0000020461258
FOXA1 / P55317 / forkhead box A1ENSG0000012951435
FOXA2 / Q9Y261 / forkhead box A2ENSG0000012579834
FOXA3 / P55318 / forkhead box A3ENSG0000017060831
FOXC1 / Q12948 / forkhead box C1ENSG0000005459830
FOXC2 / Q99958 / forkhead box C2ENSG0000017669229
FOXS1 / O43638 / forkhead box S1ENSG0000017977226
FOXL2 / P58012 / forkhead box L2ENSG0000018377025
FOXL1 / Q12952 / forkhead box L1ENSG0000017667824
FOXI1 / Q12951 / forkhead box I1ENSG0000016826922
FOXI2 / Q6ZQN5 / forkhead box I2ENSG0000018676622
FOXI3 / A8MTJ6 / forkhead box I3ENSG0000021433622


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001655 urogenital system development IEA
 biological_processGO:0001756 somitogenesis IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007412 axon target recognition IEA
 biological_processGO:0007595 lactation IEA
 biological_processGO:0008542 visual learning IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0021510 spinal cord development IEA
 biological_processGO:0021767 mammillary body development IEA
 biological_processGO:0021794 thalamus development IEA
 biological_processGO:0021855 hypothalamus cell migration IEA
 biological_processGO:0022029 telencephalon cell migration IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030901 midbrain development IEA
 biological_processGO:0033504 floor plate development IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0061030 epithelial cell differentiation involved in mammary gland alveolus development IEA
 biological_processGO:0061374 mammillothalamic axonal tract development IEA
 biological_processGO:0061377 mammary gland lobule development IEA
 biological_processGO:0061379 inferior colliculus development IEA
 biological_processGO:0061381 cell migration in diencephalon IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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