ENSG00000170608


Homo sapiens

Features
Gene ID: ENSG00000170608
  
Biological name :FOXA3
  
Synonyms : forkhead box A3 / FOXA3 / P55318
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.32
Gene start: 45863989
Gene end: 45873797
  
Corresponding Affymetrix probe sets: 228463_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000304004
Ensembl peptide - ENSP00000470816
NCBI entrez gene - 3171     See in Manteia.
OMIM - 602295
RefSeq - NM_004497
RefSeq Peptide - NP_004488
swissprot - A0A024R0R3
swissprot - M0QZW5
swissprot - P55318
Ensembl - ENSG00000170608
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxa3ENSDARG00000012788Danio rerio
 Foxa3ENSMUSG00000040891Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXA1 / P55317 / forkhead box A1ENSG0000012951453
FOXA2 / Q9Y261 / forkhead box A2ENSG0000012579849
FOXC2 / Q99958 / forkhead box C2ENSG0000017669230
FOXB1 / Q99853 / forkhead box B1ENSG0000017195629
FOXC1 / Q12948 / forkhead box C1ENSG0000005459829
FOXB2 / Q5VYV0 / forkhead box B2ENSG0000020461227
FOXI1 / Q12951 / forkhead box I1ENSG0000016826925
FOXL1 / Q12952 / forkhead box L1ENSG0000017667825
FOXI3 / A8MTJ6 / forkhead box I3ENSG0000021433624
FOXI2 / Q6ZQN5 / forkhead box I2ENSG0000018676623
FOXS1 / O43638 / forkhead box S1ENSG0000017977221
FOXL2 / P58012 / forkhead box L2ENSG0000018377020


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR013638  Fork-head N-terminal
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001678 cellular glucose homeostasis TAS
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0009267 cellular response to starvation IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IMP


Pathways (from Reactome)
Pathway description
Regulation of gene expression in beta cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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