ENSG00000182162


Homo sapiens

Features
Gene ID: ENSG00000182162
  
Biological name :P2RY8
  
Synonyms : P2RY8 / P2Y receptor family member 8 / Q86VZ1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: p22.33
Gene start: 1462572
Gene end: 1537107
  
Corresponding Affymetrix probe sets: 229686_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000490211
Ensembl peptide - ENSP00000370697
NCBI entrez gene - 286530     See in Manteia.
OMIM - 300525
RefSeq - XM_011546179
RefSeq - NM_178129
RefSeq - XM_011545631
RefSeq - XM_011545632
RefSeq - XM_011546178
RefSeq - XM_005274429
RefSeq Peptide - NP_835230
swissprot - Q86VZ1
swissprot - A0A1B0GUR3
Ensembl - ENSG00000182162
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 p2ry8ENSDARG00000055560Danio rerio
 P2RY8ENSGALG00000016687Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
F2RL1 / P55085 / F2R like trypsin receptor 1ENSG0000016425131
F2R / P25116 / coagulation factor II thrombin receptorENSG0000018110430
F2RL3 / Q96RI0 / F2R like thrombin or trypsin receptor 3ENSG0000012753328
F2RL2 / O00254 / coagulation factor II thrombin receptor like 2ENSG0000016422027
GPR42 / O15529 / G protein-coupled receptor 42 (gene/pseudogene)ENSG0000012625124
FFAR3 / O14843 / free fatty acid receptor 3ENSG0000018589724
FFAR2 / O15552 / free fatty acid receptor 2ENSG0000012626223
GPR132 / Q9UNW8 / G protein-coupled receptor 132ENSG0000018348423
GPR65 / Q8IYL9 / G protein-coupled receptor 65ENSG0000014003022
GPR4 / P46093 / G protein-coupled receptor 4ENSG0000017746421
GPR68 / Q15743 / G protein-coupled receptor 68ENSG0000011971420
FFAR1 / O14842 / free fatty acid receptor 1ENSG0000012626618


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR027669  P2Y purinoceptor 8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0035025 positive regulation of Rho protein signal transduction IBA
 biological_processGO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway IEA
 biological_processGO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA
 molecular_functionGO:0045028 G-protein coupled purinergic nucleotide receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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