ENSG00000185897


Homo sapiens

Features
Gene ID: ENSG00000185897
  
Biological name :FFAR3
  
Synonyms : FFAR3 / free fatty acid receptor 3 / O14843
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.12
Gene start: 35358460
Gene end: 35360485
  
Corresponding Affymetrix probe sets: 221385_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000328230
Ensembl peptide - ENSP00000469522
NCBI entrez gene - 2865     See in Manteia.
OMIM - 603821
RefSeq - NM_005304
RefSeq Peptide - NP_005295
swissprot - A0A0K0PUW7
swissprot - O14843
Ensembl - ENSG00000185897
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU855821.1ENSDARG00000079661Danio rerio
 si:ch211-231m23.4ENSDARG00000041292Danio rerio
 si:ch73-90p23.1ENSDARG00000097901Danio rerio
 si:dkey-211g8.6ENSDARG00000063088Danio rerio
 si:dkey-211g8.7ENSDARG00000058535Danio rerio
 Ffar3ENSMUSG00000019429Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPR42 / O15529 / G protein-coupled receptor 42 (gene/pseudogene)ENSG0000012625198
FFAR2 / O15552 / free fatty acid receptor 2ENSG0000012626238
FFAR1 / O14842 / free fatty acid receptor 1ENSG0000012626627
F2R / P25116 / coagulation factor II thrombin receptorENSG0000018110425
P2RY8 / Q86VZ1 / P2Y receptor family member 8ENSG0000018216225
F2RL1 / P55085 / F2R like trypsin receptor 1ENSG0000016425125
F2RL3 / Q96RI0 / F2R like thrombin or trypsin receptor 3ENSG0000012753325
GPR4 / P46093 / G protein-coupled receptor 4ENSG0000017746422
GPR68 / Q15743 / G protein-coupled receptor 68ENSG0000011971420
GPR132 / Q9UNW8 / G protein-coupled receptor 132ENSG0000018348419
F2RL2 / O00254 / coagulation factor II thrombin receptor like 2ENSG0000016422019
GPR65 / Q8IYL9 / G protein-coupled receptor 65ENSG0000014003018


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR013312  G protein-coupled receptor 40-related receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002385 mucosal immune response ISS
 biological_processGO:0002720 positive regulation of cytokine production involved in immune response ISS
 biological_processGO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus ISS
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway IDA
 biological_processGO:0014061 regulation of norepinephrine secretion ISS
 biological_processGO:0032722 positive regulation of chemokine production ISS
 biological_processGO:0045776 negative regulation of blood pressure ISS
 biological_processGO:0046885 regulation of hormone biosynthetic process ISS
 biological_processGO:0071398 cellular response to fatty acid IDA
 biological_processGO:0090276 regulation of peptide hormone secretion ISS
 biological_processGO:2001275 positive regulation of glucose import in response to insulin stimulus ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IDA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
Free fatty acid receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr