ENSG00000126262


Homo sapiens

Features
Gene ID: ENSG00000126262
  
Biological name :FFAR2
  
Synonyms : FFAR2 / free fatty acid receptor 2 / O15552
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.12
Gene start: 35443907
Gene end: 35451767
  
Corresponding Affymetrix probe sets: 221345_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473159
Ensembl peptide - ENSP00000246549
NCBI entrez gene - 2867     See in Manteia.
OMIM - 603823
RefSeq - XM_017026711
RefSeq - NM_005306
RefSeq - XM_017026709
RefSeq - XM_017026710
RefSeq Peptide - NP_005297
swissprot - C6KYL4
swissprot - O15552
Ensembl - ENSG00000126262
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU855821.1ENSDARG00000079661Danio rerio
 si:ch211-231m23.4ENSDARG00000041292Danio rerio
 si:ch73-90p23.1ENSDARG00000097901Danio rerio
 si:dkey-211g8.6ENSDARG00000063088Danio rerio
 si:dkey-211g8.7ENSDARG00000058535Danio rerio
 Ffar2ENSMUSG00000051314Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FFAR3 / O14843 / free fatty acid receptor 3ENSG0000018589740
GPR42 / O15529 / G protein-coupled receptor 42 (gene/pseudogene)ENSG0000012625140
FFAR1 / O14842 / free fatty acid receptor 1ENSG0000012626626
P2RY8 / Q86VZ1 / P2Y receptor family member 8ENSG0000018216225
F2R / P25116 / coagulation factor II thrombin receptorENSG0000018110423
F2RL1 / P55085 / F2R like trypsin receptor 1ENSG0000016425122
GPR4 / P46093 / G protein-coupled receptor 4ENSG0000017746422
F2RL3 / Q96RI0 / F2R like thrombin or trypsin receptor 3ENSG0000012753322
F2RL2 / O00254 / coagulation factor II thrombin receptor like 2ENSG0000016422021
GPR68 / Q15743 / G protein-coupled receptor 68ENSG0000011971420
GPR132 / Q9UNW8 / G protein-coupled receptor 132ENSG0000018348419
GPR65 / Q8IYL9 / G protein-coupled receptor 65ENSG0000014003019


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR013312  G protein-coupled receptor 40-related receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002232 leukocyte chemotaxis involved in inflammatory response ISS
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002385 mucosal immune response ISS
 biological_processGO:0002673 regulation of acute inflammatory response ISS
 biological_processGO:0002720 positive regulation of cytokine production involved in immune response ISS
 biological_processGO:0002752 cell surface pattern recognition receptor signaling pathway IMP
 biological_processGO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus ISS
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0019915 lipid storage ISS
 biological_processGO:0032722 positive regulation of chemokine production ISS
 biological_processGO:0042593 glucose homeostasis ISS
 biological_processGO:0045444 fat cell differentiation ISS
 biological_processGO:0071398 cellular response to fatty acid IDA
 biological_processGO:0090276 regulation of peptide hormone secretion ISS
 biological_processGO:2000484 positive regulation of interleukin-8 secretion IMP
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
Free fatty acid receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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