ENSG00000177464


Homo sapiens

Features
Gene ID: ENSG00000177464
  
Biological name :GPR4
  
Synonyms : GPR4 / G protein-coupled receptor 4 / P46093
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.32
Gene start: 45589764
Gene end: 45602208
  
Corresponding Affymetrix probe sets: 206236_at (Human Genome U133 Plus 2.0 Array)   211266_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000319744
NCBI entrez gene - 2828     See in Manteia.
OMIM - 600551
RefSeq - XM_017026608
RefSeq - NM_005282
RefSeq - XM_017026607
RefSeq Peptide - NP_005273
swissprot - P46093
Ensembl - ENSG00000177464
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpr4ENSDARG00000079479Danio rerio
 Gpr4ENSMUSG00000044317Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPR68 / Q15743 / G protein-coupled receptor 68ENSG0000011971446
GPR65 / Q8IYL9 / G protein-coupled receptor 65ENSG0000014003036
GPR132 / Q9UNW8 / G protein-coupled receptor 132ENSG0000018348431
F2RL1 / P55085 / F2R like trypsin receptor 1ENSG0000016425124
F2RL3 / Q96RI0 / F2R like thrombin or trypsin receptor 3ENSG0000012753324
F2RL2 / O00254 / coagulation factor II thrombin receptor like 2ENSG0000016422023
FFAR3 / O14843 / free fatty acid receptor 3ENSG0000018589721
P2RY8 / Q86VZ1 / P2Y receptor family member 8ENSG0000018216221
FFAR2 / O15552 / free fatty acid receptor 2ENSG0000012626220
F2R / P25116 / coagulation factor II thrombin receptorENSG0000018110420
GPR42 / O15529 / G protein-coupled receptor 42 (gene/pseudogene)ENSG0000012625120
FFAR1 / O14842 / free fatty acid receptor 1ENSG0000012626617


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR002276  G protein-coupled receptor 4 orphan
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0010447 response to acidic pH IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0035025 positive regulation of Rho protein signal transduction IBA
 biological_processGO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway IBA
 biological_processGO:0060055 angiogenesis involved in wound healing IEA
 biological_processGO:0072144 glomerular mesangial cell development IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS


Pathways (from Reactome)
Pathway description
Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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