ENSG00000198753


Homo sapiens

Features
Gene ID: ENSG00000198753
  
Biological name :PLXNB3
  
Synonyms : plexin B3 / PLXNB3 / Q9ULL4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q28
Gene start: 153764196
Gene end: 153779346
  
Corresponding Affymetrix probe sets: 205957_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000442736
Ensembl peptide - ENSP00000391650
Ensembl peptide - ENSP00000355378
Ensembl peptide - ENSP00000396048
Ensembl peptide - ENSP00000412454
NCBI entrez gene - 5365     See in Manteia.
OMIM - 300214
RefSeq - NM_001163257
RefSeq - NM_005393
RefSeq Peptide - NP_001156729
RefSeq Peptide - NP_005384
swissprot - Q9ULL4
swissprot - H7BZV5
swissprot - H7C0P4
swissprot - H7C3L0
Ensembl - ENSG00000198753
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plxnb3ENSDARG00000032990Danio rerio
 Plxnb3ENSMUSG00000031385Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O43157 / PLXNB1 / plexin B1ENSG0000016405051
O15031 / PLXNB2 / plexin B2ENSG0000019657639
PLXNA4 / Q9HCM2 / plexin A4ENSG0000022186633
PLXNA1 / Q9UIW2 / plexin A1ENSG0000011455433
PLXND1 / Q9Y4D7 / plexin D1ENSG0000000439933
O75051 / PLXNA2 / plexin A2ENSG0000007635633
P51805 / PLXNA3 / plexin A3ENSG0000013082732
O60486 / PLXNC1 / plexin C1ENSG0000013604022


Protein motifs (from Interpro)
Interpro ID Name
 IPR001627  Sema domain
 IPR002165  Plexin repeat
 IPR002909  IPT domain
 IPR008936  Rho GTPase activation protein
 IPR013548  Plexin, cytoplasmic RasGAP domain
 IPR013783  Immunoglobulin-like fold
 IPR014756  Immunoglobulin E-set
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016201  PSI domain
 IPR031148  Plexin family
 IPR036352  Sema domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IMP
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IDA
 biological_processGO:0007162 negative regulation of cell adhesion IDA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0010593 negative regulation of lamellipodium assembly IEA
 biological_processGO:0010976 positive regulation of neuron projection development IDA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0034260 negative regulation of GTPase activity IMP
 biological_processGO:0048675 axon extension IBA
 biological_processGO:0050772 positive regulation of axonogenesis IBA
 biological_processGO:0050918 positive chemotaxis IDA
 biological_processGO:0060326 cell chemotaxis IDA
 biological_processGO:0071526 semaphorin-plexin signaling pathway IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017154 semaphorin receptor activity IDA
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0051022 Rho GDP-dissociation inhibitor binding IEA
 molecular_functionGO:0098632 cell-cell adhesion mediator activity IPI


Pathways (from Reactome)
Pathway description
Other semaphorin interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000112902 Q13591 / SEMA5A / semaphorin 5A  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr