ENSG00000198914


Homo sapiens

Features
Gene ID: ENSG00000198914
  
Biological name :POU3F3
  
Synonyms : P20264 / POU3F3 / POU class 3 homeobox 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q12.1
Gene start: 104855511
Gene end: 104858574
  
Corresponding Affymetrix probe sets: 208563_x_at (Human Genome U133 Plus 2.0 Array)   228780_at (Human Genome U133 Plus 2.0 Array)   237008_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355001
NCBI entrez gene - 5455     See in Manteia.
OMIM - 602480
RefSeq - NM_006236
RefSeq Peptide - NP_006227
swissprot - P20264
Ensembl - ENSG00000198914
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P31361ENSMUSG00000045515Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P20265 / POU3F2 / POU class 3 homeobox 2ENSG0000018448654
POU3F1 / Q03052 / POU class 3 homeobox 1ENSG0000018566850
P49335 / POU3F4 / POU class 3 homeobox 4ENSG0000019676749
P14859 / POU2F1 / POU class 2 homeobox 1ENSG0000014319031
P09086 / POU2F2 / POU class 2 homeobox 2ENSG0000002827729
POU2F3 / Q9UKI9 / POU class 2 homeobox 3ENSG0000013770928
POU5F1 / Q01860 / POU class 5 homeobox 1ENSG0000020453126
Q06416 / POU5F1B / POU class 5 homeobox 1BENSG0000021299325
POU4F2 / Q12837 / POU class 4 homeobox 2ENSG0000015161523
P28069 / POU1F1 / POU class 1 homeobox 1ENSG0000006483522
POU4F1 / Q01851 / POU class 4 homeobox 1ENSG0000015219221
POU4F3 / Q15319 / POU class 4 homeobox 3ENSG0000009101021
POU5F2 / Q8N7G0 / POU domain class 5, transcription factor 2ENSG0000024848318


Protein motifs (from Interpro)
Interpro ID Name
 IPR000327  POU-specific domain
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily
 IPR013847  POU domain
 IPR016362  POU-domain transcription factor, class 3
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007417 central nervous system development TAS
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007588 excretion IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010628 positive regulation of gene expression ISS
 biological_processGO:0021799 cerebral cortex radially oriented cell migration IEA
 biological_processGO:0021869 forebrain ventricular zone progenitor cell division IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048878 chemical homeostasis IEA
 biological_processGO:0072218 metanephric ascending thin limb development IEA
 biological_processGO:0072227 metanephric macula densa development IEA
 biological_processGO:0072233 metanephric thick ascending limb development IEA
 biological_processGO:0072236 metanephric loop of Henle development IEA
 biological_processGO:0072240 metanephric DCT cell differentiation IEA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0043565 sequence-specific DNA binding ISS
 molecular_functionGO:0071837 HMG box domain binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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