ENSG00000212993


Homo sapiens

Features
Gene ID: ENSG00000212993
  
Biological name :POU5F1B
  
Synonyms : POU5F1B / POU class 5 homeobox 1B / Q06416
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q24.21
Gene start: 127322183
Gene end: 127420066
  
Corresponding Affymetrix probe sets: 208286_x_at (Human Genome U133 Plus 2.0 Array)   210905_x_at (Human Genome U133 Plus 2.0 Array)   214532_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000495779
Ensembl peptide - ENSP00000419298
NCBI entrez gene - 5462     See in Manteia.
OMIM - 615739
RefSeq - NM_001159542
RefSeq Peptide - NP_001153014
swissprot - Q06416
Ensembl - ENSG00000212993
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pou5f3ENSDARG00000044774Danio rerio
 Pou5f3ENSGALG00000031482Gallus gallus
 P20263ENSMUSG00000024406Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
POU5F1 / Q01860 / POU class 5 homeobox 1ENSG0000020453196
POU5F2 / Q8N7G0 / POU domain class 5, transcription factor 2ENSG0000024848345
P14859 / POU2F1 / POU class 2 homeobox 1ENSG0000014319035
POU2F3 / Q9UKI9 / POU class 2 homeobox 3ENSG0000013770935
P20264 / POU3F3 / POU class 3 homeobox 3ENSG0000019891434
P09086 / POU2F2 / POU class 2 homeobox 2ENSG0000002827734
P49335 / POU3F4 / POU class 3 homeobox 4ENSG0000019676734
POU3F1 / Q03052 / POU class 3 homeobox 1ENSG0000018566832
P20265 / POU3F2 / POU class 3 homeobox 2ENSG0000018448631
P28069 / POU1F1 / POU class 1 homeobox 1ENSG0000006483528
POU4F2 / Q12837 / POU class 4 homeobox 2ENSG0000015161527
POU4F3 / Q15319 / POU class 4 homeobox 3ENSG0000009101026
POU4F1 / Q01851 / POU class 4 homeobox 1ENSG0000015219225


Protein motifs (from Interpro)
Interpro ID Name
 IPR000327  POU-specific domain
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily
 IPR013847  POU domain
 IPR015585  POU domain-containing protein, class 5
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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